Masad J. Damha
Masad J. Damha
Distinguished James McGill Professor
Verifisert e-postadresse på mcgill.ca - Startside
Sitert av
Sitert av
Designing chemically modified oligonucleotides for targeted gene silencing
GF Deleavey, MJ Damha
Chemistry & biology 19 (8), 937-954, 2012
Chemically modified siRNA: tools and applications
JK Watts, GF Deleavey, MJ Damha
Drug discovery today 13 (19-20), 842-855, 2008
Fiber-optic DNA sensor for fluorometric nucleic acid determination
PAE Piunno, UJ Krull, RHE Hudson, MJ Damha, H Cohen
Analytical chemistry 67 (15), 2635-2643, 1995
i-Motif DNA: structural features and significance to cell biology
H Abou Assi, M Garavís, C González, MJ Damha
Nucleic acids research 46 (16), 8038-8056, 2018
Hybrids of RNA and arabinonucleic acids (ANA and 2 ‘F-ANA) are substrates of ribonuclease H
MJ Damha, CJ Wilds, A Noronha, I Brukner, G Borkow, D Arion, ...
Journal of the American Chemical Society 120 (49), 12976-12977, 1998
Improvements in siRNA properties mediated by 2′-deoxy-2′-fluoro-β- d -arabinonucleic acid (FANA)
T Dowler, D Bergeron, AL Tedeschi, L Paquet, N Ferrari, MJ Damha
Nucleic acids research 34 (6), 1669-1675, 2006
An improved procedure for derivatization of controlled-pore glass beads for solid-phase oligonucleotide synthesis
MJ Damha, PA Giannaris, SV Zabarylo
Nucleic Acids Research 18 (13), 3813-3821, 1990
2′-Deoxy-2′-fluoro-β-D-arabinonucleosides and oligonucleotides (2′ F-ANA): synthesis and physicochemical studies
CJ Wilds, MJ Damha
Nucleic acids research 28 (18), 3625-3635, 2000
Fiber optic biosensor for fluorimetric detection of DNA hybridization
PAE Piunno, UJ Krull, RHE Hudson, MJ Damha, H Cohen
Analytica Chimica Acta 288 (3), 205-214, 1994
Nucleic acid dendrimers: novel biopolymer structures
RHE Hudson, MJ Damha
Journal of the American Chemical Society 115 (6), 2119-2124, 1993
Oligoribonucleotide synthesis: the silyl-phosphoramidite method
MJ Damha, KK Ogilvie
Protocols for oligonucleotides and analogs: Synthesis and properties, 81-114, 1993
Allele-Selective Inhibition of Mutant Huntingtin Expression with Antisense Oligonucleotides Targeting the Expanded CAG Repeat
KT Gagnon, HM Pendergraff, GF Deleavey, EE Swayze, P Potier, ...
Biochemistry 49 (47), 10166-10178, 2010
Recent progress in non-native nucleic acid modifications
LK McKenzie, R El-Khoury, JD Thorpe, MJ Damha, M Hollenstein
Chemical Society Reviews 50 (8), 5126-5164, 2021
G-quadruplex induced stabilization by 2′-deoxy-2′-fluoro-d-arabinonucleic acids (2′F-ANA)
CG Peng, MJ Damha
Nucleic acids research 35 (15), 4977-4988, 2007
2′-Deoxy-2′-fluoro-β- d -arabinonucleic acid (2′F-ANA) modified oligonucleotides (ON) effect highly efficient, and persistent, gene silencing
A Kalota, L Karabon, CR Swider, E Viazovkina, M Elzagheid, MJ Damha, ...
Nucleic acids research 34 (2), 451-461, 2006
Synthesis and Biophysical Properties of Arabinonucleic Acids (ANA): Circular Dichroic Spectra, Melting Temperatures, and Ribonuclease H Susceptibility of ANA⊙ RNA Hybrid Duplexes
AM Noronha, CJ Wilds, CN Lok, K Viazovkina, D Arion, MA Parniak, ...
Biochemistry 39 (24), 7050-7062, 2000
Oligoribonucleotides containing 2′, 5′-phosphodiester linkages exhibit binding selectivity for 3′, 5′-RNA over 3′, 5′-ssDNA
PA Giannaris, MJ Damha
Nucleic acids research 21 (20), 4742-4749, 1993
Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing
GF Deleavey, JK Watts, T Alain, F Robert, A Kalota, V Aishwarya, ...
Nucleic acids research 38 (13), 4547-4557, 2010
Efficient RNase H-directed cleavage of RNA promoted by antisense DNA or 2 ‘F-ANA constructs containing acyclic nucleotide inserts
MM Mangos, KL Min, E Viazovkina, A Galarneau, MI Elzagheid, ...
Journal of the American Chemical Society 125 (3), 654-661, 2003
Energetically important C− H··· F− C pseudohydrogen bonding in water: evidence and application to rational design of oligonucleotides with high binding affinity
MY Anzahaee, JK Watts, NR Alla, AW Nicholson, MJ Damha
Journal of the American Chemical Society 133 (4), 728-731, 2011
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Artikler 1–20