Masad J. Damha

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Robert HudsonThe University of Western OntarioVerifisert e-postadresse på uwo.ca
Jonathan K. WattsProfessor, RNA Therapeutics Institute, UMass Medical SchoolVerifisert e-postadresse på umassmed.edu
Carlos González (0000-0001-8796-1...Research Professor at CSIC.Verifisert e-postadresse på iqfr.csic.es
Saul Martinez-MonteroJohnson & JohnsonVerifisert e-postadresse på its.jnj.com
Adam KatolikMcGill UniversityVerifisert e-postadresse på mail.mcgill.ca
Hala Abou AssiPostdoctoral Associate, Duke UniversityVerifisert e-postadresse på duke.edu
Daniel O'Reilly, PhDPostdoctoral Associate, University of Massachusetts Medical schoolVerifisert e-postadresse på mail.mcgill.ca
Paul PiunnoAssociate Professor, Teaching Stream, Analytical Chemistry, University of Toronto MississaugaVerifisert e-postadresse på utoronto.ca
Professor Mohamed Ibrahim ElzagheidAssociate Professor at Jubail Ind. College and Professor at Libyan Authority for Scientific ResearchVerifisert e-postadresse på RCJY.EDU.SA
Mark M. SomozaAssociate Professor of Chemistry, University of ViennaVerifisert e-postadresse på somoza.net
Modesto OrozcoProfessor of Biochemistry, Universtity of BarcelonaVerifisert e-postadresse på irbbarcelona.org
Kalle GehringMcGill UniversityVerifisert e-postadresse på mcgill.ca
Rami N Hannoush, Ph.D.Genentech, McGill, HarvardVerifisert e-postadresse på post.harvard.edu
Tak-Hang ChanProfessor, McGill UniversityVerifisert e-postadresse på mcgill.ca
Jean-Christophe LerouxETH ZürichVerifisert e-postadresse på ethz.ch
Guillem PortellaAstraZenecaVerifisert e-postadresse på astrazeneca.com
Jory LietardUniversity of ViennaVerifisert e-postadresse på univie.ac.at
Keith T. GagnonSouthern Illinois UniversityVerifisert e-postadresse på siu.edu
David CoreyVerifisert e-postadresse på utsouthwestern.edu
P. John HartEwing Halsell/President's Council Distinguished Chair in BiochemistryVerifisert e-postadresse på biochem.uthscsa.edu

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Masad J. Damha

Distinguished James McGill Professor

Verifisert e-postadresse på mcgill.ca - Startside

XNA/DNA/RNA Synthesis Gene Silencing (siRNA/ASO)CRISPR-Cas9/Cas12a G4/iM-quadruplexes Green Chemistry


Tittel Sorter etter sitater Sorter etter år Sorter etter tittel	Sitert av Sitert av	År
Designing chemically modified oligonucleotides for targeted gene silencing GF Deleavey, MJ Damha Chemistry & biology 19 (8), 937-954, 2012	639	2012
Chemically modified siRNA: tools and applications JK Watts, GF Deleavey, MJ Damha Drug discovery today 13 (19-20), 842-855, 2008	502	2008
Fiber-optic DNA sensor for fluorometric nucleic acid determination PAE Piunno, UJ Krull, RHE Hudson, MJ Damha, H Cohen Analytical chemistry 67 (15), 2635-2643, 1995	316	1995
i-Motif DNA: structural features and significance to cell biology H Abou Assi, M Garavís, C González, MJ Damha Nucleic Acids Research 46 (16), 8038-8056, 2018	259	2018
Hybrids of RNA and arabinonucleic acids (ANA and 2 ‘F-ANA) are substrates of ribonuclease H MJ Damha, CJ Wilds, A Noronha, I Brukner, G Borkow, D Arion, ... Journal of the American Chemical Society 120 (49), 12976-12977, 1998	253	1998
An improved procedure for derivatization of controlled-pore glass beads for solid-phase oligonucleotide synthesis MJ Damha, PA Giannaris, SV Zabarylo Nucleic Acids Research 18 (13), 3813-3821, 1990	230	1990
Fiber optic biosensor for fluorimetric detection of DNA hybridization PAE Piunno, UJ Krull, RHE Hudson, MJ Damha, H Cohen Analytica Chimica Acta 288 (3), 205-214, 1994	220	1994
Improvements in siRNA properties mediated by 2′-deoxy-2′-fluoro-β- d -arabinonucleic acid (FANA) T Dowler, D Bergeron, AL Tedeschi, L Paquet, N Ferrari, MJ Damha Nucleic acids research 34 (6), 1669-1675, 2006	219	2006
2′-Deoxy-2′-fluoro-β-D-arabinonucleosides and oligonucleotides (2′ F-ANA): synthesis and physicochemical studies CJ Wilds, MJ Damha Nucleic acids research 28 (18), 3625-3635, 2000	217	2000
Nucleic acid dendrimers: novel biopolymer structures RHE Hudson, MJ Damha Journal of the American Chemical Society 115 (6), 2119-2124, 1993	185	1993
Oligoribonucleotide synthesis: the silyl-phosphoramidite method MJ Damha, KK Ogilvie Protocols for oligonucleotides and analogs: Synthesis and properties, 81-114, 1993	170	1993
Allele-Selective Inhibition of Mutant Huntingtin Expression with Antisense Oligonucleotides Targeting the Expanded CAG Repeat KT Gagnon, HM Pendergraff, GF Deleavey, EE Swayze, P Potier, ... Biochemistry 49 (47), 10166-10178, 2010	163	2010
G-quadruplex induced stabilization by 2′-deoxy-2′-fluoro-d-arabinonucleic acids (2′F-ANA) CG Peng, MJ Damha Nucleic acids research 35 (15), 4977-4988, 2007	145	2007
Synthesis and Biophysical Properties of Arabinonucleic Acids (ANA): Circular Dichroic Spectra, Melting Temperatures, and Ribonuclease H Susceptibility of ANA⊙ RNA Hybrid Duplexes AM Noronha, CJ Wilds, CN Lok, K Viazovkina, D Arion, MA Parniak, ... Biochemistry 39 (24), 7050-7062, 2000	131	2000
Oligoribonucleotides containing 2′, 5′-phosphodiester linkages exhibit binding selectivity for 3′, 5′-RNA over 3′, 5′-ssDNA PA Giannaris, MJ Damha Nucleic acids research 21 (20), 4742-4749, 1993	128	1993
2′-Deoxy-2′-fluoro-β- d -arabinonucleic acid (2′F-ANA) modified oligonucleotides (ON) effect highly efficient, and persistent, gene silencing A Kalota, L Karabon, CR Swider, E Viazovkina, M Elzagheid, MJ Damha, ... Nucleic acids research 34 (2), 451-461, 2006	124	2006
Recent progress in non-native nucleic acid modifications LK McKenzie, R El-Khoury, JD Thorpe, MJ Damha, M Hollenstein Chemical Society Reviews 50 (8), 5126-5164, 2021	122	2021
Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing GF Deleavey, JK Watts, T Alain, F Robert, A Kalota, V Aishwarya, ... Nucleic acids research 38 (13), 4547-4557, 2010	116	2010
Efficient RNase H-directed cleavage of RNA promoted by antisense DNA or 2 ‘F-ANA constructs containing acyclic nucleotide inserts MM Mangos, KL Min, E Viazovkina, A Galarneau, MI Elzagheid, ... Journal of the American Chemical Society 125 (3), 654-661, 2003	109	2003
2′-Fluoro-4′-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity JK Watts, N Choubdar, K Sadalapure, F Robert, AS Wahba, J Pelletier, ... Nucleic acids research 35 (5), 1441-1451, 2007	103	2007

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