Andriy Luzhetskyy
Andriy Luzhetskyy
Group Leader of Actinobacteria Metabolic Engineering group at Helmholtz Institute for Pharmaceutical
Verifisert e-postadresse på helmholtz-hzi.de
TittelSitert avÅr
Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork
C Hertweck, A Luzhetskyy, Y Rebets, A Bechthold
Natural product reports 24 (1), 162-190, 2007
4482007
Minimum information about a biosynthetic gene cluster
MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ...
Nature chemical biology 11 (9), 625-631, 2015
3642015
β-Glucuronidase as a sensitive and versatile reporter in actinomycetes
M Myronovskyi, E Welle, V Fedorenko, A Luzhetskyy
Appl. Environ. Microbiol. 77 (15), 5370-5383, 2011
1412011
Design, construction and characterisation of a synthetic promoter library for fine-tuned gene expression in actinomycetes
T Siegl, B Tokovenko, M Myronovskyi, A Luzhetskyy
Metabolic engineering 19, 98-106, 2013
1102013
Insights into naturally minimised Streptomyces albus J1074 genome
N Zaburannyi, M Rabyk, B Ostash, V Fedorenko, A Luzhetskyy
BMC genomics 15 (1), 97, 2014
1042014
Site-specific recombination strategies for engineering actinomycete genomes
S Herrmann, T Siegl, M Luzhetska, L Petzke, C Jilg, E Welle, A Erb, ...
Appl. Environ. Microbiol. 78 (6), 1804-1812, 2012
772012
Glycosyltransferases, important tools for drug design
A Luzhetskyy, C Mendez, JA Salas, A Bechthold
Current topics in medicinal chemistry 8 (8), 680-709, 2008
752008
The future of natural products as a source of new antibiotics.
A Luzhetskyy, S Pelzer, A Bechthold
Current opinion in investigational drugs (London, England: 2000) 8 (8), 608-613, 2007
752007
Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tü6071: analysis of the gene cluster and generation of derivatives
C Dürr, HJ Schnell, A Luzhetskyy, R Murillo, M Weber, K Welzel, A Vente, ...
Chemistry & biology 13 (4), 365-377, 2006
742006
Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus
B Ostash, U Rix, LLR Rix, T Liu, F Lombo, A Luzhetskyy, O Gromyko, ...
Chemistry & biology 11 (4), 547-555, 2004
702004
Functional expression of the Cre recombinase in actinomycetes
M Fedoryshyn, E Welle, A Bechthold, A Luzhetskyy
Applied microbiology and biotechnology 78 (6), 1065-1070, 2008
672008
Iteratively acting glycosyltransferases involved in the hexasaccharide biosynthesis of landomycin A
A Luzhetskyy, M Fedoryshyn, C Dürr, T Taguchi, V Novikov, A Bechthold
Chemistry & biology 12 (7), 725-729, 2005
652005
Marker removal from actinomycetes genome using Flp recombinase
M Fedoryshyn, L Petzke, E Welle, A Bechthold, A Luzhetskyy
Gene 419 (1-2), 43-47, 2008
642008
Cloning and heterologous expression of the aranciamycin biosynthetic gene cluster revealed a new flexible glycosyltransferase
A Luzhetskyy, A Mayer, J Hoffmann, S Pelzer, M Holzenkämper, B Schmitt, ...
ChemBioChem 8 (6), 599-602, 2007
552007
Identification of the Function of Gene l ndM2 Encoding a Bifunctional Oxygenase-Reductase Involved in the Biosynthesis of the Antitumor Antibiotic Landomycin E by Streptomyces …
L Zhu, B Ostash, U Rix, M Nur-e-Alam, A Mayers, A Luzhetskyy, ...
The Journal of organic chemistry 70 (2), 631-638, 2005
552005
Generation of New Landomycins with Altered Saccharide Patterns through Over‐expression of the Glycosyltransferase Gene lanGT3 in the Biosynthetic Gene Cluster of …
L Zhu, A Luzhetskyy, M Luzhetska, C Mattingly, V Adams, A Bechthold, ...
ChemBioChem 8 (1), 83-88, 2007
542007
Generation of novel landomycins M and O through targeted gene disruption
A Luzhetskyy, L Zhu, M Gibson, M Fedoryshyn, C Dürr, C Hofmann, ...
ChemBioChem 6 (4), 675-678, 2005
542005
Expression of the landomycin biosynthetic gene cluster in a PKS mutant of Streptomyces fradiae is dependent on the coexpression of a putative transcriptional …
VU Mulert, A Luzhetskyy, C Hofmann, A Mayer, A Bechthold
FEMS microbiology letters 230 (1), 91-97, 2004
532004
LanGT2 catalyzes the first glycosylation step during landomycin A biosynthesis
A Luzhetskyy, T Taguchi, M Fedoryshyn, C Dürr, SE Wohlert, V Novikov, ...
ChemBioChem 6 (8), 1406-1410, 2005
522005
Glycosyltransferases involved in the biosynthesis of biologically active natural products that contain oligosaccharides
A Luzhetskyy, A Vente, A Bechthold
Molecular BioSystems 1 (2), 117-126, 2005
502005
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Artikler 1–20