A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β JJ Iliff, M Wang, Y Liao, BA Plogg, W Peng, GA Gundersen, H Benveniste, ... Science translational medicine 4 (147), 147ra111-147ra111, 2012 | 5287 | 2012 |
Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain S Nielsen, EA Nagelhus, M Amiry-Moghaddam, C Bourque, P Agre, ... Journal of Neuroscience 17 (1), 171-180, 1997 | 1724 | 1997 |
Physiological roles of aquaporin-4 in brain EA Nagelhus, OP Ottersen Physiological reviews 93 (4), 1543-1562, 2013 | 770 | 2013 |
Aquaporin-4 in the central nervous system: cellular and subcellular distribution and coexpression with KIR4. 1 EA Nagelhus, TM Mathiisen, OP Ottersen Neuroscience 129 (4), 905-913, 2004 | 635 | 2004 |
Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Müller cells is mediated by a coenrichment of Kir4.1 and AQP4 in … EA Nagelhus, Y Horio, A Inanobe, A Fujita, F Haug, S Nielsen, Y Kurachi, ... Glia 26 (1), 47-54, 1999 | 587 | 1999 |
Aquaporin-4 water channel protein in the rat retina and optic nerve: polarized expression in Müller cells and fibrous astrocytes EA Nagelhus, ML Veruki, R Torp, FM Haug, JH Laake, S Nielsen, P Agre, ... Journal of Neuroscience 18 (7), 2506-2519, 1998 | 536 | 1998 |
Delayed K+ clearance associated with aquaporin-4 mislocalization: phenotypic defects in brains of α-syntrophin-null mice M Amiry-Moghaddam, A Williamson, M Palomba, T Eid, NC De Lanerolle, ... Proceedings of the National Academy of Sciences 100 (23), 13615-13620, 2003 | 451 | 2003 |
Aquaporins in complex tissues: distribution of aquaporins 1–5 in human and rat eye S Hamann, T Zeuthen, ML Cour, EA Nagelhus, OP Ottersen, P Agre, ... American Journal of Physiology-Cell Physiology 274 (5), C1332-C1345, 1998 | 380 | 1998 |
Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood–brain water uptake and confers barrier function on perivascular astrocyte endfeet NN Haj-Yasein, GF Vindedal, M Eilert-Olsen, GA Gundersen, Ø Skare, ... Proceedings of the National Academy of Sciences 108 (43), 17815-17820, 2011 | 370 | 2011 |
Impaired glymphatic function and clearance of tau in an Alzheimer’s disease model IF Harrison, O Ismail, A Machhada, N Colgan, Y Ohene, P Nahavandi, ... Brain 143 (8), 2576-2593, 2020 | 361 | 2020 |
General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex AS Thrane, V Rangroo Thrane, D Zeppenfeld, N Lou, Q Xu, EA Nagelhus, ... Proceedings of the National Academy of Sciences 109 (46), 18974-18979, 2012 | 332 | 2012 |
Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema AS Thrane, PM Rappold, T Fujita, A Torres, LK Bekar, T Takano, W Peng, ... Proceedings of the National Academy of Sciences 108 (2), 846-851, 2011 | 316 | 2011 |
Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering V Rangroo Thrane, AS Thrane, F Wang, ML Cotrina, NA Smith, M Chen, ... Nature medicine 19 (12), 1643-1648, 2013 | 297 | 2013 |
Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow KE Holter, B Kehlet, A Devor, TJ Sejnowski, AM Dale, SW Omholt, ... Proceedings of the National Academy of Sciences 114 (37), 9894-9899, 2017 | 271 | 2017 |
Ontogeny of water transport in rat brain: Postnatal expression of the aquaporin‐4 water channel H Wen, EA Nagelhus, M Amiry‐Moghaddam, P Agre, OP Ottersen, ... European Journal of Neuroscience 11 (3), 935-945, 1999 | 215 | 1999 |
Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain VR Thrane, AS Thrane, BA Plog, M Thiyagarajan, JJ Iliff, R Deane, ... Scientific reports 3 (1), 2582, 2013 | 208 | 2013 |
LTP induction boosts glutamate spillover by driving withdrawal of perisynaptic astroglia C Henneberger, L Bard, A Panatier, JP Reynolds, O Kopach, ... Neuron 108 (5), 919-936. e11, 2020 | 197 | 2020 |
Aquaporin‐4 and epilepsy DK Binder, EA Nagelhus, OP Ottersen Glia 60 (8), 1203-1214, 2012 | 195 | 2012 |
Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep L Bojarskaite, DM Bjørnstad, KH Pettersen, C Cunen, GH Hermansen, ... Nature communications 11 (1), 3240, 2020 | 177 | 2020 |
Dynamics of ionic shifts in cortical spreading depression R Enger, W Tang, GF Vindedal, V Jensen, P Johannes Helm, R Sprengel, ... Cerebral Cortex 25 (11), 4469-4476, 2015 | 177 | 2015 |