Codon usage of highly expressed genes affects proteome-wide translation efficiency I Frumkin, MJ Lajoie, CJ Gregg, G Hornung, GM Church, Y Pilpel Proceedings of the National Academy of Sciences 115 (21), E4940-E4949, 2018 | 200 | 2018 |
Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes K Krumpe*, I Frumkin*, et al, (*equal contribution) Molecular biology of the cell 23 (20), 3927-3935, 2012 | 152 | 2012 |
Mitochondrial 16S rRNA is methylated by tRNA methyltransferase TRMT61B in all vertebrates D Bar-Yaacov, I Frumkin, Y Yashiro, T Chujo, Y Ishigami, Y Chemla, ... PLoS biology 14 (9), e1002557, 2016 | 117 | 2016 |
tRNA genes rapidly change in evolution to meet novel translational demands AH Yona*, Z Bloom-Ackermann*, I Frumkin*, et al, (*equal contribution) Elife 2, e01339, 2013 | 109 | 2013 |
Gene Architectures that Minimize Cost of Gene Expression I Frumkin*, D Schirman*, A Rotman*, et al, (*equal contribution) Molecular Cell 65 (1), 142-153, 2017 | 102 | 2017 |
A relay race on the evolutionary adaptation spectrum AH Yona, I Frumkin, Y Pilpel Cell 163 (3), 549-559, 2015 | 75 | 2015 |
The yeast ER-intramembrane protease Ypf1 refines nutrient sensing by regulating transporter abundance D Avci, S Fuchs, B Schrul, A Fukumori, M Breker, I Frumkin, C Chen, ... Molecular cell 56 (5), 630-640, 2014 | 63 | 2014 |
Manipulation of the human tRNA pool reveals distinct tRNA sets that act in cellular proliferation or cell cycle arrest N Aharon-Hefetz, I Frumkin, Y Mayshar, O Dahan, Y Pilpel, R Rak Elife 9, e58461, 2020 | 33 | 2020 |
Evolution of intron splicing towards optimized gene expression is based on various Cis- and Trans-molecular mechanisms I Frumkin, I Yofe, R Bar-Ziv, Y Gurvich, YY Lu, Y Voichek, R Towers, ... PLoS biology 17 (8), e3000423, 2019 | 18 | 2019 |
Selection of a de novo gene that can promote survival of Escherichiacoli by modulating protein homeostasis pathways I Frumkin, MT Laub Nature Ecology & Evolution 7 (12), 2067-2079, 2023 | 13 | 2023 |
Does cancer strive to minimize the cost of gene expression? D Schirman, I Frumkin, Y Pilpel Oncotarget 9 (46), 27909, 2018 | | 2018 |
Elucidating evolutionary and regulatory mechanisms of cellular machineries of the central dogma I Frumkin Weizmann Institute of Science, 0 | | |