Jon S. Thorson

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Shanteri SinghAssistant Professor of Department of Chemistry and Biochemistry at the University of Oklahoma.Verifisert e-postadresse på ou.edu
George N. Phillips, Jr.BioSciences at Rice UniversityVerifisert e-postadresse på rice.edu
Steven G. Van LanenUniversity of KentuckyVerifisert e-postadresse på uky.edu
Changsheng ZhangProfessor of Marine Chemical Microbiology, South China Sea Institute of OceanologyVerifisert e-postadresse på scsio.ac.cn
Madan KharelAssistant Prof. of Pharmaceutical sciences, University of Maryland Eastern ShoreVerifisert e-postadresse på umes.edu
Jurgen RohrProfessor of Bioorganic Chemistry, University of KentuckyVerifisert e-postadresse på email.uky.edu
Andrew J. MorrisStony Brook, University of North Carolina, University of KentuckyVerifisert e-postadresse på uky.edu
Yinan ZhangNanjing University of Chinese MedicineVerifisert e-postadresse på njucm.edu.cn
Ben ShenThe Scripps Research InstituteVerifisert e-postadresse på scripps.edu
James C. HowerUniversity of Kentucky Center for Applied Energy ResearchVerifisert e-postadresse på uky.edu
Joseph LangenhanSeattle UniversityVerifisert e-postadresse på seattleu.edu
Richard GanttDupont Industrial BiosciencesVerifisert e-postadresse på wisc.edu
Gavin WilliamsProfessor of Chemistry, NC State UniversityVerifisert e-postadresse på ncsu.edu
Chirlei GlienkePROFESSOR UNIVERSIDADE FEDERAL DO PARANAVerifisert e-postadresse på ufpr.br
Stephen Randal VossDepartment of Neuroscience, University of KentuckyVerifisert e-postadresse på uky.edu
Chang-Guo ZhanProfessor of Pharmaceutical Sciences, University of KentuckyVerifisert e-postadresse på uky.edu
Qing-Bai SheProfessor of Molecular Pharmacology, University of KentuckyVerifisert e-postadresse på uky.edu
Wen LiuSouth China Agricultural UniversityVerifisert e-postadresse på stu.scau.edu.cn
Eli ChapmanThe University of ArizonaVerifisert e-postadresse på pharmacy.arizona.edu
Brian O. BachmannAssociate Professor of Chemistry, Vanderbilt UniversityVerifisert e-postadresse på vanderbilt.edu

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Jon S. Thorson

Professor and Associate Dean of Research, University of Kentucky College of Pharmacy

Verifisert e-postadresse på uky.edu - Startside

Natural products discovery biosynthesis enzyme engineering


Tittel Sorter etter sitater Sorter etter år Sorter etter tittel	Sitert av Sitert av	År
Antitumor antibiotics: Bleomycin, enediynes, and mitomycin U Galm, MH Hager, SG Van Lanen, J Ju, JS Thorson, B Shen Chemical Reviews 105 (2), 739-758, 2005	642	2005
Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells MW Nowak, PC Kearney, JR Sampson, ME Saks, CG Labarca, ... Science 268 (5209), 439-439, 1995	444	1995
A genomics-guided approach for discovering and expressing cryptic metabolic pathways E Zazopoulos, K Huang, A Staffa, W Liu, BO Bachmann, K Nonaka, ... Nature Biotechnology 21 (2), 187-190, 2003	404	2003
A comprehensive review of glycosylated bacterial natural products SI Elshahawi, KA Shaaban, MK Kharel, JS Thorson Chemical Society Reviews 44 (21), 7591-7697, 2015	388	2015
The calicheamicin gene cluster and its iterative type I enediyne PKS J Ahlert, E Shepard, N Lomovskaya, E Zazopoulos, A Staffa, ... Science 297 (5584), 1173-1176, 2002	368	2002
Structure, activity, synthesis and biosynthesis of aryl-C-glycosides T Bililign, BR Griffith, JS Thorson Natural Product Reports 22 (6), 742-760, 2005	362	2005
Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria H Liu, JS Thorson Annual Reviews in Microbiology 48 (1), 223-256, 1994	358	1994
Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions C Zhang, BR Griffith, Q Fu, C Albermann, X Fu, IK Lee, L Li, JS Thorson Science 313 (5791), 1291-1294, 2006	323	2006
Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution GJ Williams, C Zhang, JS Thorson Nature Chemical Biology 3 (10), 657-662, 2007	311	2007
Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization JM Langenhan, NR Peters, IA Guzei, FM Hoffmann, JS Thorson Proceedings of the National Academy of Sciences 102 (35), 12305-12310, 2005	291	2005
Antibiotic optimization via in vitro glycorandomization X Fu, C Albermann, J Jiang, J Liao, C Zhang, JS Thorson Nature Biotechnology 21 (12), 1467-1469, 2003	272	2003
Enzymatic methods for glyco (diversification/randomization) of drugs and small molecules RW Gantt, P Peltier-Pain, JS Thorson Natural Product Reports 28 (11), 1811-1853, 2011	265	2011
Nature's carbohydrate chemists: The enzymatic glycosylation of bioactive bacterial metabolites JS Thorson, TJ Hosted Jr, J Jiang, JB Biggins, J Ahlert Current Organic Chemistry 5 (2), 139-167, 2001	218	2001
Understanding and exploiting nature's chemical arsenal: The past, present and future of calicheamicin research JS Thorson, EL Sievers, J Ahlert, E Shepard, RE Whitwam, KC Onwueme, ... Current Pharmaceutical Design 6 (18), 1841-1879, 2000	213	2000
‘Sweetening’natural products via glycorandomization BR Griffith, JM Langenhan, JS Thorson Current Opinion in Biotechnology 16 (6), 622-630, 2005	187	2005
Enzymatic tools for engineering natural product glycosylation S Blanchard, JS Thorson Current Opinion in Chemical Biology 10 (3), 263-271, 2006	184	2006
Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides HC Losey, J Jiang, JB Biggins, M Oberthür, XY Ye, SD Dong, D Kahne, ... Chemistry & Biology 9 (12), 1305-1314, 2002	180	2002
Neoglycorandomization and chemoenzymatic glycorandomization: Two complementary tools for natural product diversification JM Langenhan, BR Griffith, JS Thorson Journal of Natural Products 68 (11), 1696-1711, 2005	177	2005
Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation A Chang, S Singh, GN Phillips Jr, JS Thorson Current Opinion in Biotechnology 22 (6), 800-808, 2011	173	2011
Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization WA Barton, J Lesniak, JB Biggins, PD Jeffrey, J Jiang, KR Rajashankar, ... Nature Structural Biology 8 (6), 545-551, 2001	164	2001

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