Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature GI Rice, PR Kasher, GMA Forte, NM Mannion, SM Greenwood, ... Nature genetics 44 (11), 1243-1248, 2012 | 844 | 2012 |
The RNA-editing enzyme ADAR1 controls innate immune responses to RNA NM Mannion, SM Greenwood, R Young, S Cox, J Brindle, D Read, ... Cell reports 9 (4), 1482-1494, 2014 | 571 | 2014 |
Dynamic landscape and regulation of RNA editing in mammals MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Nature 550 (7675), 249-254, 2017 | 531 | 2017 |
A-to-I pre-mRNA editing in Drosophila is primarily involved in adult nervous system function and integrity MJ Palladino, LP Keegan, MA O'Connell, RA Reenan Cell 102 (4), 437-449, 2000 | 453 | 2000 |
Identifying RNA editing sites using RNA sequencing data alone G Ramaswami, R Zhang, R Piskol, LP Keegan, P Deng, MA O'connell, ... Nature methods 10 (2), 128-132, 2013 | 385 | 2013 |
The many roles of an RNA editor LP Keegan, A Gallo, MA O'Connell Nature Reviews Genetics 2 (11), 869-878, 2001 | 365 | 2001 |
Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase MA O'Connell, S Krause, M Higuchi, JJ Hsuan, NF Totty, A Jenny, ... Molecular and cellular biology 15 (3), 1389-1397, 1995 | 320 | 1995 |
Dynamic association of RNA-editing enzymes with the nucleolus JMP Desterro, LP Keegan, M Lafarga, MT Berciano, M O'Connell, ... Journal of cell science 116 (9), 1805-1818, 2003 | 317 | 2003 |
A standardized nomenclature for adenosine deaminases that act on RNA. BL Bass, K Nishikura, W Keller, PH Seeburg, RB Emeson, MA O'connell, ... Rna 3 (9), 947, 1997 | 288 | 1997 |
Two forms of human double-stranded RNA-specific editase 1 (hRED1) generated by the insertion of an Alu cassette. A Gerber, MA O'Connell, W Keller Rna 3 (5), 453, 1997 | 239 | 1997 |
Down-regulation of RNA editing in pediatric astrocytomas: ADAR2 editing activity inhibits cell migration and proliferation C Cenci, R Barzotti, F Galeano, S Corbelli, R Rota, L Massimi, C Di Rocco, ... Journal of Biological Chemistry 283 (11), 7251-7260, 2008 | 229 | 2008 |
dADAR, a Drosophila double-stranded RNA-specific adenosine deaminase is highly developmentally regulated and is itself a target for RNA editing MJ Palladino, LP Keegan, MA O'CONNELL, RA Reenan Rna 6 (7), 1004-1018, 2000 | 226 | 2000 |
Microsatellite DNA analysis of population structure in Atlantic herring (Clupea harengus), with direct comparison to allozyme and mtDNA RFLP analyses PW Shaw, C Turan, JM Wright, M O’connell, GR Carvalho Heredity 83 (4), 490-499, 1999 | 216 | 1999 |
Editing independent effects of ADARs on the miRNA/siRNA pathways BSE Heale, LP Keegan, L McGurk, G Michlewski, J Brindle, CM Stanton, ... The EMBO journal 28 (20), 3145-3156, 2009 | 211 | 2009 |
Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes LP Keegan, A Leroy, D Sproul, MA O'Connell Genome biology 5, 1-10, 2004 | 176 | 2004 |
Structural requirements for RNA editing in glutamate receptor pre-mRNAs by recombinant double-stranded RNA adenosine deaminase (∗) S Maas, T Melcher, A Herb, PH Seeburg, W Keller, S Krause, M Higuchi, ... Journal of Biological Chemistry 271 (21), 12221-12226, 1996 | 167 | 1996 |
Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects R Marcucci, J Brindle, S Paro, A Casadio, S Hempel, N Morrice, A Bisso, ... The EMBO journal 30 (20), 4211-4222, 2011 | 147 | 2011 |
An ADAR that edits transcripts encoding ion channel subunits functions as a dimer A Gallo, LP Keegan, GM Ring, MA O'Connell The EMBO journal 22 (13), 3421-3430, 2003 | 143 | 2003 |
SUMO-1 modification alters ADAR1 editing activity JMP Desterro, LP Keegan, E Jaffray, RT Hay, MA O'Connell, ... Molecular biology of the cell 16 (11), 5115-5126, 2005 | 135 | 2005 |
Purification and properties of double-stranded RNA-specific adenosine deaminase from calf thymus. MA O'Connell, W Keller Proceedings of the National Academy of Sciences 91 (22), 10596-10600, 1994 | 132 | 1994 |