Elaine Holmes

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Jeremy K NicholsonAustralian National Phenome Center, Murdoch University + Imperial College LondonVerified email at murdoch.edu.au
Tim EbbelsProfessor of Biomedical Data Science, Imperial College LondonVerified email at imperial.ac.uk
Ian D WilsonImperial College, LondonVerified email at imperial.ac.uk
Hector KeunProfessor of Biochemistry, Imperial College LondonVerified email at imperial.ac.uk
Yap, Ivan KSImperial College London; Sarawak Research and Development Council; Clinical Research Centre SarawakVerified email at clinicalresearch.my
Henrik AnttiDepartment of Chemsitry, Umeå University, SwedenVerified email at chem.umu.se
Kirill VeselkovAssistant Professor, Department of Surgery and Cancer, Imperial College LondonVerified email at imperial.ac.uk
Johan TryggProfessor of Chemometrics, Umeå University, SwedenVerified email at umu.se
Huiru TangWuhan Institute of Physics and MathematicsVerified email at wipm.ac.cn
Robert PlumbWaters CorporationVerified email at waters.com
Jonathan SwannUniversity of Southampton, Imperial College London, Karolinska InstituteVerified email at soton.ac.uk
thanos athanasiouprofessor of cardiovascular sciences and cardiac surgeryVerified email at imperial.ac.uk
Beatriz JiménezNMR Divisional ManagerVerified email at imperial.ac.uk
John P. ShockcorVisiting Professor, Dept of Surgery and Cancer, Imperial College, LondonVerified email at imperial.ac.uk
Sandrine Paule ClausKing's College LondonVerified email at kcl.ac.uk
Panagiotis VorkasPostdoctoral ResearcherVerified email at imperial.ac.uk
Burton SingerAdjunct professor, Emerging Pathogens Institute, University of FloridaVerified email at epi.ufl.edu
Dr Andrew W NichollsExecutive Director and Head of Bioimaging, GlaxoSmithKlineVerified email at gsk.com
Fergus ShanahanUniversity College Cork, National University of IrelandVerified email at ucc.ie
Cristina Legido-QuigleySteno Copenhagen, King's College London, Imperial College LondonVerified email at kcl.ac.uk

Elaine Holmes

Murdoch University & Imperial College London

Verified email at imperial.ac.uk

Metabonomics spectroscopy molecular epidemiology personalised medicine metabolomics


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'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data JK Nicholson, JC Lindon, E Holmes Xenobiotica 29 (11), 1181-1189, 1999	5103	1999
Host-gut microbiota metabolic interactions JK Nicholson, E Holmes, J Kinross, R Burcelin, G Gibson, W Jia, ... Science 336 (6086), 1262-1267, 2012	4932	2012
Metabonomics: a platform for studying drug toxicity and gene function JK Nicholson, J Connelly, JC Lindon, E Holmes Nature reviews Drug discovery 1 (2), 153-161, 2002	2596	2002
Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts O Beckonert, HC Keun, TMD Ebbels, J Bundy, E Holmes, JC Lindon, ... Nature protocols 2 (11), 2692, 2007	2347	2007
Chemometrics in metabonomics J Trygg, E Holmes, T Lundstedt Journal of proteome research 6 (2), 469-479, 2007	1595	2007
OPLS discriminant analysis: combining the strengths of PLS‐DA and SIMCA classification M Bylesjö, M Rantalainen, O Cloarec, JK Nicholson, E Holmes, J Trygg Journal of Chemometrics: A Journal of the Chemometrics Society 20 (8‐10 …, 2006	1544	2006
Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics JT Brindle, H Antti, E Holmes, G Tranter, JK Nicholson, HWL Bethell, ... Nature medicine 8 (12), 1439-1445, 2002	1440	2002
Symbiotic gut microbes modulate human metabolic phenotypes M Li, B Wang, M Zhang, M Rantalainen, S Wang, H Zhou, Y Zhang, ... Proceedings of the National Academy of Sciences 105 (6), 2117-2122, 2008	1363	2008
Gut microbiomes of Malawian twin pairs discordant for kwashiorkor MI Smith, T Yatsunenko, MJ Manary, I Trehan, R Mkakosya, J Cheng, ... Science 339 (6119), 548-554, 2013	1303	2013
Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice ME Dumas, RH Barton, A Toye, O Cloarec, C Blancher, A Rothwell, ... Proceedings of the national academy of sciences 103 (33), 12511-12516, 2006	1292	2006
750 MHz 1H and 1H-13C NMR spectroscopy of human blood plasma JK Nicholson, PJD Foxall, M Spraul, RD Farrant, JC Lindon Analytical chemistry 67 (5), 793-811, 1995	1222	1995
Human metabolic phenotype diversity and its association with diet and blood pressure E Holmes, RL Loo, J Stamler, M Bictash, IKS Yap, Q Chan, T Ebbels, ... Nature 453 (7193), 396-400, 2008	1216	2008
Gut microorganisms, mammalian metabolism and personalized health care JK Nicholson, E Holmes, ID Wilson Nature Reviews Microbiology 3 (5), 431-438, 2005	1202	2005
Global metabolic profiling procedures for urine using UPLC–MS EJ Want, ID Wilson, H Gika, G Theodoridis, RS Plumb, J Shockcor, ... Nature protocols 5 (6), 1005-1018, 2010	1126	2010
Global metabolic profiling of animal and human tissues via UPLC-MS EJ Want, P Masson, F Michopoulos, ID Wilson, G Theodoridis, RS Plumb, ... Nature protocols 8 (1), 17-32, 2013	1033	2013
Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets O Cloarec, ME Dumas, A Craig, RH Barton, J Trygg, J Hudson, ... Analytical chemistry 77 (5), 1282-1289, 2005	1032	2005
Metabolic phenotyping in health and disease E Holmes, ID Wilson, JK Nicholson Cell 134 (5), 714-717, 2008	941	2008
Systemic gut microbial modulation of bile acid metabolism in host tissue compartments JR Swann, EJ Want, FM Geier, K Spagou, ID Wilson, JE Sidaway, ... Proceedings of the National Academy of Sciences 108 (supplement_1), 4523-4530, 2011	844	2011
Rapid and noninvasive metabonomic characterization of inflammatory bowel disease JR Marchesi, E Holmes, F Khan, S Kochhar, P Scanlan, F Shanahan, ... Journal of proteome research 6 (2), 546-551, 2007	748	2007
Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2 DA Collier, IATM Ferreira, P Kotagiri, RP Datir, EY Lim, E Touizer, B Meng, ... Nature 596 (7872), 417-422, 2021	672	2021

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