| Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2. L Buscail, N Delesque, JP Esteve, N Saint-Laurent, H Prats, P Clerc, ... Proceedings of the National Academy of Sciences 91 (6), 2315-2319, 1994 | 397 | 1994 |
| Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms. L Buscail, JP Esteve, N Saint-Laurent, V Bertrand, T Reisine, AM O'Carroll, ... Proceedings of the National Academy of Sciences 92 (5), 1580-1584, 1995 | 356 | 1995 |
| Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer L Buscail, N Saint-Laurent, E Chastre, JC Vaillant, C Gespach, G Capellà, ... Cancer Research 56 (8), 1823-1827, 1996 | 279 | 1996 |
| The tyrosine phosphatase SHP-1 associates with the sst2 somatostatin receptor and is an essential component of sst2-mediated inhibitory growth signaling F Lopez, JP Esteve, L Buscail, N Delesque, N Saint-Laurent, M Théveniau, ... Journal of Biological Chemistry 272 (39), 24448-24454, 1997 | 201 | 1997 |
| Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis J Guillermet, N Saint-Laurent, P Rochaix, O Cuvillier, T Levade, ... Proceedings of the National Academy of Sciences 100 (1), 155-160, 2003 | 190 | 2003 |
| sst2 Somatostatin Receptor Mediates Cell Cycle Arrest and Induction of p27 Kip1: EVIDENCE FOR THE ROLE OF SHP-1 P Pages, N Benali, N Saint-Laurent, JP Esteve, AV Schally, J Tkaczuk, ... Journal of Biological Chemistry 274 (21), 15186-15193, 1999 | 186 | 1999 |
| Targeting the sphingolipid metabolism to defeat pancreatic cancer cell resistance to the chemotherapeutic gemcitabine drug J Guillermet-Guibert, L Davenne, D Pchejetski, N Saint-Laurent, ... Molecular cancer therapeutics 8 (4), 809-820, 2009 | 174 | 2009 |
| sst2 Somatostatin receptor inhibits cell proliferation through Ras-, Rap1-, and B-Raf-dependent ERK2 activation H Lahlou, N Saint-Laurent, JP Esteve, A Eychene, L Pradayrol, ... Journal of Biological Chemistry 278 (41), 39356-39371, 2003 | 152 | 2003 |
| sst2 somatostatin receptor mediates negative regulation of insulin receptor signaling through the tyrosine phosphatase SHP-1 C Bousquet, N Delesque, F Lopez, N Saint-Laurent, JP Esteve, K Bedecs, ... Journal of Biological Chemistry 273 (12), 7099-7106, 1998 | 137 | 1998 |
| sst2 somatostatin receptor expression reverses tumorigenicity of human pancreatic cancer cells N Delesque, L Buscail, JP Estève, N Saint-Laurent, C Müller, ... Cancer Research 57 (5), 956-962, 1997 | 136 | 1997 |
| Gene therapy for pancreatic carcinoma: local and distant antitumor effects after somatostatin receptor sst2 gene transfer P Rochaix, N Delesque, JP Esteve, N Saint-Laurent, JJ Voigt, N Vaysse, ... Human gene therapy 10 (6), 995-1008, 1999 | 130 | 1999 |
| First-in-man phase 1 clinical trial of gene therapy for advanced pancreatic cancer: safety, biodistribution, and preliminary clinical findings L Buscail, B Bournet, F Vernejoul, G Cambois, H Lulka, N Hanoun, ... Molecular therapy 23 (4), 779-789, 2015 | 118 | 2015 |
| Direct binding of p85 to sst2 somatostatin receptor reveals a novel mechanism for inhibiting PI3K pathway C Bousquet, J Guillermet‐Guibert, N Saint‐Laurent, E Archer‐Lahlou, ... The EMBO journal 25 (17), 3943-3954, 2006 | 106 | 2006 |
| Critical role of Src and SHP-2 in sst2 somatostatin receptor-mediated activation of SHP-1 and inhibition of cell proliferation G Ferjoux, F Lopez, JP Esteve, A Ferrand, E Vivier, F Vely, ... Molecular biology of the cell 14 (9), 3911-3928, 2003 | 102 | 2003 |
| Chronic estradiol treatment reduces platelet responses and protects mice from thromboembolism through the hematopoietic estrogen receptor α MC Valéra, MP Gratacap, P Gourdy, F Lenfant, C Cabou, CE Toutain, ... Blood, The Journal of the American Society of Hematology 120 (8), 1703-1712, 2012 | 69 | 2012 |
| Novel synergistic mechanism for sst2 somatostatin and TNFα receptors to induce apoptosis: crosstalk between NF-κB and JNK pathways J Guillermet-Guibert, N Saint-Laurent, L Davenne, P Rochaix, O Cuvillier, ... Cell Death & Differentiation 14 (2), 197-208, 2007 | 64 | 2007 |
| Neuronal nitric oxide synthase is a SHP‐1 substrate involved in sst2 somatostatin receptor growth inhibitory signaling F Lopez, G Ferjoux, P Cordelier, N Saint‐Laurent, JP Estève, N Vaysse, ... The FASEB Journal 15 (12), 1-25, 2001 | 64 | 2001 |
| Induction of a negative autocrine loop by expression of sst2 somatostatin receptor in NIH 3T3 cells. I Rauly, N Saint-Laurent, N Delesque, L Buscail, JP Estève, N Vaysse, ... The Journal of clinical investigation 97 (8), 1874-1883, 1996 | 58 | 1996 |
| Characterization of a membrane tyrosine phosphatase in AR42J cells: regulation by somatostatin N Tahiri-Jouti, C Cambillau, N Viguerie, C Vidal, L Buscail, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 262 (6 …, 1992 | 56 | 1992 |
| Molecular mechanisms of antiproliferative effect of somatostatin: involvement of a tyrosine phosphatase F Lopez, JP Esteve, L Buscail, N Delesque, N Saint-Laurent, N Vaysse, ... Metabolism 45, 14-16, 1996 | 55 | 1996 |
