Pranathi Meda Krishnamurthy
Pranathi Meda Krishnamurthy
Bristol Myers Squibb
Verifisert e-postadresse på umassmed.edu
Sitert av
Sitert av
Targeting the MLL complex in castration-resistant prostate cancer
R Malik, AP Khan, IA Asangani, M Cieślik, JR Prensner, X Wang, MK Iyer, ...
Nature medicine 21 (4), 344-352, 2015
BET bromodomain inhibitors enhance efficacy and disrupt resistance to AR antagonists in the treatment of prostate cancer
IA Asangani, K Wilder-Romans, VL Dommeti, PM Krishnamurthy, IJ Apel, ...
Molecular Cancer Research 14 (4), 324-331, 2016
KRAS protein stability is regulated through SMURF2: UBCH5 complex-mediated β-TrCP1 degradation
S Shukla, US Allam, A Ahsan, G Chen, PM Krishnamurthy, K Marsh, ...
Neoplasia 16 (2), 115-W5, 2014
EWS/ETS-driven ewing sarcoma requires BET bromodomain proteins
PN Gollavilli, A Pawar, K Wilder-Romans, R Natesan, CG Engelke, ...
Cancer research 78 (16), 4760-4773, 2018
5′ Modifications improve potency and efficacy of DNA donors for precision genome editing
KS Ghanta, GA Dokshin, A Mir, PM Krishnamurthy, H Gneid, A Edraki, ...
BioRxiv, 354480, 2018
Synthesis and biological properties of triazole-linked locked nucleic acid
VK Sharma, SK Singh, PM Krishnamurthy, JF Alterman, RA Haraszti, ...
Chemical Communications 53 (63), 8906-8909, 2017
Locked Nucleic Acid Gapmers and Conjugates Potently Silence ADAM33, an Asthma-Associated Metalloprotease with Nuclear-Localized mRNA
JKW Hannah M. Pendergraff, Pranathi Meda Krishnamurthy, Alexandre J ...
Molecular Therapy 159, 2017
Tristetraprolin mediates radiation-induced TNF-α production in lung macrophages
D Ray, S Shukla, US Allam, A Helman, SG Ramanand, L Tran, M Bassetti, ...
PloS one 8 (2), e57290, 2013
Quantification of antisense oligonucleotides by splint ligation and quantitative polymerase chain reaction
M Shin, P Meda Krishnamurthy, G Devi, JK Watts
nucleic acid therapeutics 32 (1), 66-73, 2022
Quantifying and mitigating motor phenotypes induced by antisense oligonucleotides in the central nervous system
MP Moazami, JM Rembetsy-Brown, F Wang, PM Krishnamurthy, A Weiss, ...
BioRxiv, 2021.02. 14.431096, 2021
Next-generation PNA chimeras exhibit high affinity and potent gene silencing
JW Alexandre J Debacker, Vivek K. Sharma, Pranathi Meda Krishnamurthy ...
Biochemistry, 2019
Involvement of p38-βTrCP-Tristetraprolin-TNFα axis in radiation pneumonitis
PM Krishnamurthy, S Shukla, P Ray, R Mehra, MK Nyati, TS Lawrence, ...
Oncotarget 8 (29), 47767, 2017
Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts
M Shin, IL Chan, Y Cao, AM Gruntman, J Lee, J Sousa, TC Rodríguez, ...
Nucleic Acids Research 50 (15), 8418-8430, 2022
Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection
VN Hariharan, M Shin, CW Chang, D O’Reilly, A Biscans, K Yamada, ...
Proceedings of the National Academy of Sciences 120 (11), e2219523120, 2023
CASCADES, a novel SOX2 super-enhancer associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma multiforme
biorxiv, 2020
A Khvorova, J Watts, Z Kennedy, A Biscans, BM da Cruz Godinho, ...
US Patent App. 17/333,839, 2023
G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects
F Wang, E Calvo-Roitberg, JM Rembetsy-Brown, M Fang, J Sousa, ...
Nucleic Acids Research 50 (22), 12657-12673, 2022
Quantification of Antisense Oligonucleotides by Splint Ligation and Quantitative Polymerase Chain Reaction [preprint]
M Shin, PM Krishnamurthy, JK Watts
Quantifying and Mitigating Motor Phenotypes Induced by Antisense Oligonucleotides in the Central Nervous System [preprint]
MP Moazami, JM Rembetsy-Brown, F Wang, PM Krishnamurthy, A Weiss, ...
Abstract LB-099: BET bromodomain proteins are essential for the oncogenic EWS-fusion driven Ewing Sarcoma
PN Gollavilli, A Pawar, K Wilder-Romans, C Engelke, VL Dommeti, ...
Cancer Research 77 (13_Supplement), LB-099-LB-099, 2017
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Artikler 1–20