Diverse cellular and molecular modes of axon degeneration LJ Neukomm, MR Freeman Trends in cell biology 24 (9), 515-523, 2014 | 150 | 2014 |
A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells AW Kao, RJ Eisenhut, LH Martens, A Nakamura, A Huang, JA Bagley, ... Proceedings of the National Academy of Sciences 108 (11), 4441-4446, 2011 | 140 | 2011 |
Creatine transporters: a reappraisal O Speer, LJ Neukomm, RM Murphy, E Zanolla, U Schlattner, H Henry, ... Molecular and cellular biochemistry 256, 407-424, 2004 | 117 | 2004 |
The Wnt pathway controls cell death engulfment, spindle orientation, and migration through CED-10/Rac J Cabello, LJ Neukomm, U Günesdogan, K Burkart, SJ Charette, ... PLoS biology 8 (2), e1000297, 2010 | 102 | 2010 |
Axon death pathways converge on axundead to promote functional and structural axon disassembly LJ Neukomm, TC Burdett, AM Seeds, S Hampel, JC Coutinho-Budd, ... Neuron 95 (1), 78-91. e5, 2017 | 101 | 2017 |
Age-dependent TDP-43-mediated motor neuron degeneration requires GSK3, hat-trick, and xmas-2 J Sreedharan, LJ Neukomm, RH Brown, MR Freeman Current Biology 25 (16), 2130-2136, 2015 | 93 | 2015 |
Aminophospholipid translocase TAT-1 promotes phosphatidylserine exposure during C. elegans apoptosis S Züllig, LJ Neukomm, M Jovanovic, SJ Charette, NN Lyssenko, ... Current biology 17 (11), 994-999, 2007 | 85 | 2007 |
Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns (3) P critical for the degradation of apoptotic cells N Lu, Q Shen, TR Mahoney, LJ Neukomm, Y Wang, Z Zhou PLoS biology 10 (1), e1001245, 2012 | 83 | 2012 |
Rapid in vivo forward genetic approach for identifying axon death genes in Drosophila LJ Neukomm, TC Burdett, MA Gonzalez, S Züchner, MR Freeman Proceedings of the National Academy of Sciences 111 (27), 9965-9970, 2014 | 79 | 2014 |
Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans LJ Neukomm, AP Frei, J Cabello, JM Kinchen, R Zaidel-Bar, Z Ma, ... Nature cell biology 13 (1), 79-86, 2011 | 73 | 2011 |
Axon degeneration induces glial responses through Draper-TRAF4-JNK signalling TY Lu, JM MacDonald, LJ Neukomm, AE Sheehan, R Bradshaw, ... Nature communications 8 (1), 14355, 2017 | 70 | 2017 |
Glutathione S-transferase regulates mitochondrial populations in axons through increased glutathione oxidation GA Smith, TH Lin, AE Sheehan, WVG van Naters, LJ Neukomm, ... Neuron 103 (1), 52-65. e6, 2019 | 58 | 2019 |
Axon death signalling in Wallerian degeneration among species and in disease A Llobet Rosell, LJ Neukomm Open biology 9 (8), 190118, 2019 | 56 | 2019 |
The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5–CED-12 in C. elegans LJ Neukomm, AS Nicot, JM Kinchen, J Almendinger, SM Pinto, S Zeng, ... Development 138 (10), 2003-2014, 2011 | 49 | 2011 |
Transcription factor Pebbled/RREB1 regulates injury-induced axon degeneration JE Farley, TC Burdett, R Barria, LJ Neukomm, KP Kenna, JE Landers, ... Proceedings of the National Academy of Sciences 115 (6), 1358-1363, 2018 | 46 | 2018 |
Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans LJ Neukomm, S Zeng, AP Frei, PA Huegli, MO Hengartner Cell Death & Differentiation 21 (6), 845-853, 2014 | 45 | 2014 |
RIP-chip-SRM—a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans M Jovanovic, L Reiter, A Clark, M Weiss, P Picotti, H Rehrauer, A Frei, ... Genome research 22 (7), 1360-1371, 2012 | 22 | 2012 |
The NAD+ precursor NMN activates dSarm to trigger axon degeneration in Drosophila AL Rosell, M Paglione, J Gilley, M Kocia, G Perillo, M Gasparrini, ... Elife 11, e80245, 2022 | 19 | 2022 |
Morphological and Functional Evaluation of Axons and their Synapses during Axon Death in Drosophila melanogaster M Paglione, AL Rosell, JY Chatton, LJ Neukomm JoVE, e60865, 2020 | 15 | 2020 |
Divergent signaling requirements of dSARM in injury-induced degeneration and developmental glial phagocytosis KA Herrmann, Y Liu, A Llobet-Rosell, CN McLaughlin, LJ Neukomm, ... PLoS Genetics 18 (6), e1010257, 2022 | 13 | 2022 |