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Lukas J. Neukomm
Lukas J. Neukomm
Assistant Professor, Department of Fundamental Neurosciences, University of Lausanne
Verifisert e-postadresse på unil.ch - Startside
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Diverse cellular and molecular modes of axon degeneration
LJ Neukomm, MR Freeman
Trends in cell biology 24 (9), 515-523, 2014
1502014
A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells
AW Kao, RJ Eisenhut, LH Martens, A Nakamura, A Huang, JA Bagley, ...
Proceedings of the National Academy of Sciences 108 (11), 4441-4446, 2011
1402011
Creatine transporters: a reappraisal
O Speer, LJ Neukomm, RM Murphy, E Zanolla, U Schlattner, H Henry, ...
Molecular and cellular biochemistry 256, 407-424, 2004
1172004
The Wnt pathway controls cell death engulfment, spindle orientation, and migration through CED-10/Rac
J Cabello, LJ Neukomm, U Günesdogan, K Burkart, SJ Charette, ...
PLoS biology 8 (2), e1000297, 2010
1022010
Axon death pathways converge on axundead to promote functional and structural axon disassembly
LJ Neukomm, TC Burdett, AM Seeds, S Hampel, JC Coutinho-Budd, ...
Neuron 95 (1), 78-91. e5, 2017
1012017
Age-dependent TDP-43-mediated motor neuron degeneration requires GSK3, hat-trick, and xmas-2
J Sreedharan, LJ Neukomm, RH Brown, MR Freeman
Current Biology 25 (16), 2130-2136, 2015
932015
Aminophospholipid translocase TAT-1 promotes phosphatidylserine exposure during C. elegans apoptosis
S Züllig, LJ Neukomm, M Jovanovic, SJ Charette, NN Lyssenko, ...
Current biology 17 (11), 994-999, 2007
852007
Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns (3) P critical for the degradation of apoptotic cells
N Lu, Q Shen, TR Mahoney, LJ Neukomm, Y Wang, Z Zhou
PLoS biology 10 (1), e1001245, 2012
832012
Rapid in vivo forward genetic approach for identifying axon death genes in Drosophila
LJ Neukomm, TC Burdett, MA Gonzalez, S Züchner, MR Freeman
Proceedings of the National Academy of Sciences 111 (27), 9965-9970, 2014
792014
Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans
LJ Neukomm, AP Frei, J Cabello, JM Kinchen, R Zaidel-Bar, Z Ma, ...
Nature cell biology 13 (1), 79-86, 2011
732011
Axon degeneration induces glial responses through Draper-TRAF4-JNK signalling
TY Lu, JM MacDonald, LJ Neukomm, AE Sheehan, R Bradshaw, ...
Nature communications 8 (1), 14355, 2017
702017
Glutathione S-transferase regulates mitochondrial populations in axons through increased glutathione oxidation
GA Smith, TH Lin, AE Sheehan, WVG van Naters, LJ Neukomm, ...
Neuron 103 (1), 52-65. e6, 2019
582019
Axon death signalling in Wallerian degeneration among species and in disease
A Llobet Rosell, LJ Neukomm
Open biology 9 (8), 190118, 2019
562019
The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5–CED-12 in C. elegans
LJ Neukomm, AS Nicot, JM Kinchen, J Almendinger, SM Pinto, S Zeng, ...
Development 138 (10), 2003-2014, 2011
492011
Transcription factor Pebbled/RREB1 regulates injury-induced axon degeneration
JE Farley, TC Burdett, R Barria, LJ Neukomm, KP Kenna, JE Landers, ...
Proceedings of the National Academy of Sciences 115 (6), 1358-1363, 2018
462018
Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans
LJ Neukomm, S Zeng, AP Frei, PA Huegli, MO Hengartner
Cell Death & Differentiation 21 (6), 845-853, 2014
452014
RIP-chip-SRM—a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans
M Jovanovic, L Reiter, A Clark, M Weiss, P Picotti, H Rehrauer, A Frei, ...
Genome research 22 (7), 1360-1371, 2012
222012
The NAD+ precursor NMN activates dSarm to trigger axon degeneration in Drosophila
AL Rosell, M Paglione, J Gilley, M Kocia, G Perillo, M Gasparrini, ...
Elife 11, e80245, 2022
192022
Morphological and Functional Evaluation of Axons and their Synapses during Axon Death in Drosophila melanogaster
M Paglione, AL Rosell, JY Chatton, LJ Neukomm
JoVE, e60865, 2020
152020
Divergent signaling requirements of dSARM in injury-induced degeneration and developmental glial phagocytosis
KA Herrmann, Y Liu, A Llobet-Rosell, CN McLaughlin, LJ Neukomm, ...
PLoS Genetics 18 (6), e1010257, 2022
132022
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Artikler 1–20