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David Nathanson
David Nathanson
Verifisert e-postadresse på mednet.ucla.edu - Startside
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Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
PY Wen, M Weller, EQ Lee, BM Alexander, JS Barnholtz-Sloan, ...
Neuro-oncology 22 (8), 1073-1113, 2020
6732020
Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity
KM Turner, V Deshpande, D Beyter, T Koga, J Rusert, C Lee, B Li, ...
Nature 543 (7643), 122-125, 2017
6012017
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA
DA Nathanson, B Gini, J Mottahedeh, K Visnyei, T Koga, G Gomez, ...
Science 343 (6166), 72-76, 2014
5632014
An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR–dependent pathway
D Guo, F Reinitz, M Youssef, C Hong, D Nathanson, D Akhavan, D Kuga, ...
Cancer discovery 1 (5), 442-456, 2011
4432011
Oncogenic EGFR signaling activates an mTORC2–NF-κB pathway that promotes chemotherapy resistance
K Tanaka, I Babic, D Nathanson, D Akhavan, D Guo, B Gini, J Dang, ...
Cancer discovery 1 (6), 524-538, 2011
3312011
2-Hydroxyglutarate inhibits ATP synthase and mTOR signaling
X Fu, RM Chin, L Vergnes, H Hwang, G Deng, Y Xing, MY Pai, S Li, L Ta, ...
Cell metabolism 22 (3), 508-515, 2015
2372015
EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer
I Babic, ES Anderson, K Tanaka, D Guo, K Masui, B Li, S Zhu, Y Gu, ...
Cell metabolism 17 (6), 1000-1008, 2013
1672013
De-Repression of PDGFRβ Transcription Promotes Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Glioblastoma Patients
D Akhavan, AL Pourzia, AA Nourian, KJ Williams, D Nathanson, I Babic, ...
Cancer discovery 3 (5), 534-547, 2013
1452013
An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis
G Tarcic, SK Boguslavsky, J Wakim, T Kiuchi, A Liu, F Reinitz, ...
Current Biology 19 (21), 1788-1798, 2009
1432009
Development of a real-time RT-PCR assay for detecting EGFRvIII in glioblastoma samples
K Yoshimoto, J Dang, S Zhu, D Nathanson, T Huang, R Dumont, ...
Clinical Cancer Research 14 (2), 488-493, 2008
1262008
Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240
TR Fenton, D Nathanson, C Ponte de Albuquerque, D Kuga, A Iwanami, ...
Proceedings of the National Academy of Sciences 109 (35), 14164-14169, 2012
1232012
Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress
WR Austin, AL Armijo, DO Campbell, AS Singh, T Hsieh, D Nathanson, ...
Journal of Experimental Medicine 209 (12), 2215-2228, 2012
1162012
A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens
J Sun, MD Masterman-Smith, NA Graham, J Jiao, J Mottahedeh, DR Laks, ...
Cancer research 70 (15), 6128-6138, 2010
1152010
PET/CT in oncology: current status and perspectives
J Czernin, M Allen-Auerbach, D Nathanson, K Herrmann
Current radiology reports 1, 177-190, 2013
1072013
Chemical methods for the simultaneous quantitation of metabolites and proteins from single cells
M Xue, W Wei, Y Su, J Kim, YS Shin, WX Mai, DA Nathanson, JR Heath
Journal of the American Chemical Society 137 (12), 4066-4069, 2015
1052015
Neoadjuvant PD-1 blockade induces T cell and cDC1 activation but fails to overcome the immunosuppressive tumor associated macrophages in recurrent glioblastoma
AH Lee, L Sun, AY Mochizuki, JG Reynoso, J Orpilla, F Chow, JC Kienzler, ...
Nature communications 12 (1), 6938, 2021
1012021
Brain-mimetic 3D culture platforms allow investigation of cooperative effects of extracellular matrix features on therapeutic resistance in glioblastoma
W Xiao, R Zhang, A Sohrabi, A Ehsanipour, S Sun, J Liang, CM Walthers, ...
Cancer research 78 (5), 1358-1370, 2018
902018
Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma
WX Mai, L Gosa, VW Daniels, L Ta, JE Tsang, B Higgins, WB Gilmore, ...
Nature medicine 23 (11), 1342-1351, 2017
882017
Microfluidic imaging cytometry
H Tseng, K Kamei, J Sun, PS Mischel, MD Masterman-Smith, ...
US Patent App. 12/863,526, 2010
662010
Expression of PD-1 by T cells in malignant glioma patients reflects exhaustion and activation
TB Davidson, A Lee, M Hsu, S Sedighim, J Orpilla, J Treger, M Mastall, ...
Clinical Cancer Research 25 (6), 1913-1922, 2019
642019
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