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Thomas Schwarzl
Thomas Schwarzl
EMBL
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A brave new world of RNA-binding proteins
MW Hentze, A Castello, T Schwarzl, T Preiss
Nature reviews Molecular cell biology 19 (5), 327-341, 2018
14812018
RNA-binding proteins in human genetic disease
F Gebauer, T Schwarzl, J Valcárcel, MW Hentze
Nature Reviews Genetics 22 (3), 185-198, 2021
4742021
The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs
BM Beckmann, R Horos, B Fischer, A Castello, K Eichelbaum, ...
Nature communications 6 (1), 10127, 2015
4632015
The human RNA-binding proteome and its dynamics during translational arrest
J Trendel, T Schwarzl, R Horos, A Prakash, A Bateman, MW Hentze, ...
Cell 176 (1), 391-403. e19, 2019
3492019
Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription
J Rauch, E O'Neill, B Mack, C Matthias, M Munz, W Kolch, O Gires
Cancer research 70 (4), 1679-1688, 2010
181*2010
Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture
JI Perez-Perri, B Rogell, T Schwarzl, F Stein, Y Zhou, M Rettel, A Brosig, ...
Nature communications 9 (1), 4408, 2018
1772018
The small non-coding vault RNA1-1 acts as a riboregulator of autophagy
R Horos, M Büscher, R Kleinendorst, AM Alleaume, AK Tarafder, ...
Cell 176 (5), 1054-1067. e12, 2019
1392019
GeneSigDB—a curated database of gene expression signatures
AC Culhane, T Schwarzl, R Sultana, KC Picard, SC Picard, TH Lu, ...
Nucleic acids research 38 (suppl_1), D716-D725, 2010
1192010
FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation
J Popow, AM Alleaume, T Curk, T Schwarzl, S Sauer, MW Hentze
Rna 21 (11), 1873-1884, 2015
1122015
GSK3 Inhibitors Regulate MYCN mRNA Levels and Reduce Neuroblastoma Cell Viability through Multiple Mechanisms, Including p53 and Wnt Signaling
DJ Duffy, A Krstic, T Schwarzl, DG Higgins, W Kolch
Molecular cancer therapeutics 13 (2), 454-467, 2014
912014
Exon junction complexes show a distributional bias toward alternatively spliced mRNAs and against mRNAs coding for ribosomal proteins
C Hauer, J Sieber, T Schwarzl, I Hollerer, T Curk, AM Alleaume, ...
Cell reports 16 (6), 1588-1603, 2016
752016
The RNA-binding protein YBX3 controls amino acid levels by regulating SLC mRNA abundance
A Cooke, T Schwarzl, I Huppertz, G Kramer, P Mantas, AM Alleaume, ...
Cell reports 27 (11), 3097-3106. e5, 2019
592019
Riboregulation of Enolase 1 activity controls glycolysis and embryonic stem cell differentiation
I Huppertz, JI Perez-Perri, P Mantas, T Sekaran, T Schwarzl, F Russo, ...
Molecular cell 82 (14), 2666-2680. e11, 2022
502022
Plasticity of nuclear and cytoplasmic stress responses of RNA-binding proteins
M Backlund, F Stein, M Rettel, T Schwarzl, JI Perez-Perri, A Brosig, ...
Nucleic acids research 48 (9), 4725-4740, 2020
482020
Retinoic acid and TGF-β signalling cooperate to overcome MYCN-induced retinoid resistance
DJ Duffy, A Krstic, M Halasz, T Schwarzl, A Konietzny, K Iljin, DG Higgins, ...
Genome medicine 9, 1-22, 2017
422017
An integrated global analysis of compartmentalized HRAS signaling
T Santra, A Herrero, J Rodriguez, A von Kriegsheim, LF Iglesias-Martinez, ...
Cell reports 26 (11), 3100-3115. e7, 2019
412019
Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma
DJ Duffy, A Krstic, M Halasz, T Schwarzl, D Fey, K Iljin, JP Mehta, K Killick, ...
Oncotarget 6 (41), 43182, 2015
372015
Improved binding site assignment by high-resolution mapping of RNA-protein interactions using iCLIP
C Hauer, T Curk, S Anders, T Schwarzl, AM Alleaume, J Sieber, I Hollerer, ...
Nature communications 6, 7921, 2015
342015
Wnt signalling is a bi-directional vulnerability of cancer cells
DJ Duffy, A Krstic, T Schwarzl, M Halasz, K Iljin, D Fey, B Haley, J Whilde, ...
Oncotarget 7 (37), 60310, 2016
322016
Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner
SF Fitzpatrick, Z Fábián, B Schaible, CR Lenihan, T Schwarzl, ...
Biochemical and Biophysical Research Communications 474 (3), 579-586, 2016
322016
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Artikler 1–20