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Edward Kalkreuter
Edward Kalkreuter
Postdoc, UF Scripps
Verifisert e-postadresse på scripps.edu
Tittel
Sitert av
Sitert av
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MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters
BR Terlouw, K Blin, JC Navarro-Muñoz, NE Avalon, MG Chevrette, ...
Nucleic acids research 51 (D1), D603-D610, 2023
1282023
Targeting bacterial genomes for natural product discovery
E Kalkreuter, G Pan, AJ Cepeda, B Shen
Trends in Pharmacological Sciences 41 (1), 13-26, 2020
832020
Engineering the substrate specificity of a modular polyketide synthase for installation of consecutive non-natural extender units
E Kalkreuter, JM CroweTipton, AN Lowell, DH Sherman, GJ Williams
Journal of the American Chemical Society 141 (5), 1961-1969, 2019
472019
Engineering enzymatic assembly lines for the production of new antimicrobials
E Kalkreuter, GJ Williams
Current opinion in microbiology 45, 140-148, 2018
382018
Characterization and crystal structure of a nonheme diiron monooxygenase involved in platensimycin and platencin biosynthesis
LB Dong, YC Liu, AJ Cepeda, E Kalkreuter, MR Deng, JD Rudolf, ...
Journal of the American Chemical Society 141 (31), 12406-12412, 2019
272019
Cryptic and stereospecific hydroxylation, oxidation, and reduction in platensimycin and platencin biosynthesis
LB Dong, X Zhang, JD Rudolf, MR Deng, E Kalkreuter, AJ Cepeda, ...
Journal of the American Chemical Society 141 (9), 4043-4050, 2019
262019
Development of a Genetically Encoded Biosensor for Detection of Polyketide Synthase Extender Units in Escherichia coli
E Kalkreuter, AM Keeler, AA Malico, KS Bingham, AK Gayen, GJ Williams
ACS synthetic biology 8 (6), 1391-1400, 2019
232019
Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase
E Kalkreuter, KS Bingham, AM Keeler, AN Lowell, JJ Schmidt, ...
Nature Communications 12, 2193, 2021
222021
Cryptic sulfur incorporation in thioangucycline biosynthesis
M Cao, C Zheng, D Yang, E Kalkreuter, A Adhikari, YC Liu, ME Rateb, ...
Angewandte Chemie 133 (13), 7216-7223, 2021
132021
Thiocysteine lyases as polyketide synthase domains installing hydropersulfide into natural products and a hydropersulfide methyltransferase
S Meng, AD Steele, W Yan, G Pan, E Kalkreuter, YC Liu, Z Xu, B Shen
Nature Communications 12 (1), 5672, 2021
92021
Stem cell patents—reexamination/litigation—the last 5 years
Y Shyntum, E Kalkreuter
Tissue Engineering Part B: Reviews 15 (1), 87-90, 2009
92009
Intramolecular C–C bond formation links anthraquinone and enediyne scaffolds in tiancimycin biosynthesis
C Gui, E Kalkreuter, YC Liu, A Adhikari, CN Teijaro, D Yang, C Chang, ...
Journal of the American Chemical Society 144 (44), 20452-20462, 2022
82022
A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products
M Bhardwaj, Z Cui, E Daniel Hankore, FH Moonschi, ...
Proceedings of the National Academy of Sciences 120 (9), e2220468120, 2023
72023
PtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine N-Acetyltransferases
CJ Zheng, E Kalkreuter, BY Fan, YC Liu, LB Dong, B Shen
ACS chemical biology 16 (1), 96-105, 2020
52020
Precursor-directed biosynthesis and semi-synthesis of natural products
E Kalkreuter, SM Carpenter, GJ Williams
42018
Hybrid Peptide–Polyketide Natural Product Biosynthesis
AD Steele, E Kalkreuter, G Pan, S Meng, B Shen
Elsevier, 2020
22020
Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis
C Gui, E Kalkreuter, YC Liu, G Li, AD Steele, D Yang, C Chang, B Shen
Nature Chemical Biology 20 (2), 243-250, 2024
12024
Discrete Acyltransferases and Thioesterases in Iso-Migrastatin and Lactimidomycin Biosynthesis
AD Steele, H Jiang, G Pan, SK Lim, E Kalkreuter, T Kwong, J Ju, S Rajski, ...
Biochemistry, 2024
2024
Development of platensimycin, platencin, and platensilin overproducers by biosynthetic pathway engineering and fermentation medium optimization
LL Fluegel, MR Deng, P Su, E Kalkreuter, D Yang, JD Rudolf, LB Dong, ...
Journal of Industrial Microbiology and Biotechnology, kuae003, 2024
2024
TAILORED HETEROLOGOUS ACTINOBACTERIAL PRODUCERS INSPIRED BY NATIVE NATURAL PRODUCT PRODUCERS.
C Davis, C Gui, E Kalkreuter, L Lauterbach, B Shen
4th International Conference on Natural Product Discovery and Development in …, 2023
2023
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Artikler 1–20