Shanshan Wu Howland
Shanshan Wu Howland
Singapore Immunology Network
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Single-cell analysis of human mononuclear phagocytes reveals subset-defining markers and identifies circulating inflammatory dendritic cells
CA Dutertre, E Becht, SE Irac, A Khalilnezhad, V Narang, S Khalilnezhad, ...
Immunity 51 (3), 573-589. e8, 2019
A rapid and robust tri-color flow cytometry assay for monitoring malaria parasite development
B Malleret, C Claser, ASM Ong, R Suwanarusk, K Sriprawat, SW Howland, ...
Scientific reports 1 (1), 118, 2011
Cerebral malaria: mysteries at the blood-brain barrier
L Rénia, SW Howland, C Claser, AC Gruner, R Suwanarusk, TH Teo, ...
Virulence 3 (2), 193-201, 2012
CD8+ T cells and IFN-γ mediate the time-dependent accumulation of infected red blood cells in deep organs during experimental cerebral malaria
C Claser, B Malleret, SY Gun, AYW Wong, ZW Chang, P Teo, PCE See, ...
PloS one 6 (4), e18720, 2011
Brain microvessel cross‐presentation is a hallmark of experimental cerebral malaria
SW Howland, CM Poh, SY Gun, C Claser, B Malleret, N Shastri, ...
EMBO molecular medicine 5 (7), 984-999, 2013
Stability and CDR composition biases enrich binder functionality landscapes
BJ Hackel, ME Ackerman, SW Howland, KD Wittrup
Journal of molecular biology 401 (1), 84-96, 2010
A practical approach to immunotherapy of hepatocellular carcinoma using T cells redirected against hepatitis B virus
S Koh, N Shimasaki, R Suwanarusk, ZZ Ho, A Chia, N Banu, SW Howland, ...
Molecular Therapy-Nucleic Acids 2, 2013
Activated brain endothelial cells cross-present malaria antigen
SW Howland, CM Poh, L Rénia
PLoS pathogens 11 (6), e1004963, 2015
Pathogenic CD8+ T cells in experimental cerebral malaria
SW Howland, C Claser, CM Poh, SY Gun, L Rénia
Seminars in immunopathology 37, 221-231, 2015
A subset of Kupffer cells regulates metabolism through the expression of CD36
C Blériot, E Barreby, G Dunsmore, R Ballaire, S Chakarov, X Ficht, ...
Immunity 54 (9), 2101-2116. e6, 2021
Cross-reactive dengue human monoclonal antibody prevents severe pathologies and death from Zika virus infections
YW Kam, CYP Lee, TH Teo, SW Howland, SN Amrun, FM Lum, P See, ...
JCI insight 2 (8), 2017
Antigen release kinetics in the phagosome are critical to cross-presentation efficiency
SW Howland, KD Wittrup
The Journal of Immunology 180 (3), 1576-1583, 2008
Damage to the Blood-Brain Barrier during Experimental Cerebral Malaria Results from Synergistic Effects of CD8+ T Cells with Different Specificities
CM Poh, SW Howland, GM Grotenbreg, L Rénia
Infection and immunity 82 (11), 4854-4864, 2014
Directed evolution for improved secretion of cancer–testis antigen NY-ESO-1 from yeast
A Piatesi, SW Howland, JA Rakestraw, C Renner, N Robson, J Cebon, ...
Protein expression and purification 48 (2), 232-242, 2006
Methods and compositions for increased priming of t-cells through cross-presentation of exogenous antigens
SW Howland, L Old, KD Wittrup
US Patent App. 11/834,910, 2008
Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury
C Claser, SYT Nguee, A Balachander, S Wu Howland, E Becht, ...
Nature Communications 10 (1), 4241, 2019
Nerve growth factor receptor-mediated gene transfer
N Ma, SS Wu, YX Ma, X Wang, J Zeng, G Tong, Y Huang, S Wang
Molecular Therapy 9 (2), 270-281, 2004
Recombinant polypeptide useful for neurotrophin receptor mediated gene delivery and as neurotrophin agonist
S Wang, SS Wu, J Zeng, N Ma
US Patent 7,205,387, 2007
Inducing efficient cross-priming using antigen-coated yeast particles
SW Howland, T Tsuji, S Gnjatic, G Ritter, LJ Old, KD Wittrup
Journal of immunotherapy (Hagerstown, Md.: 1997) 31 (7), 607, 2008
Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells
B Malleret, A El Sahili, MZ Tay, G Carissimo, ASM Ong, W Novera, J Lin, ...
Nature microbiology 6 (8), 991-999, 2021
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