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Linda Liau
Linda Liau
Professor & Chair of Neurosurgery, UCLA
Verifisert e-postadresse på mednet.ucla.edu - Startside
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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
L Dang, DW White, S Gross, BD Bennett, MA Bittinger, EM Driggers, ...
Nature 462 (7274), 739-744, 2009
45582009
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
IK Mellinghoff, MY Wang, I Vivanco, DA Haas-Kogan, S Zhu, EQ Dia, ...
New England Journal of Medicine 353 (19), 2012-2024, 2005
17182005
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma
R Beroukhim, G Getz, L Nghiemphu, J Barretina, T Hsueh, D Linhart, ...
Proceedings of the National Academy of Sciences 104 (50), 20007-20012, 2007
12342007
High-throughput oncogene mutation profiling in human cancer
RK Thomas, AC Baker, RM DeBiasi, W Winckler, T LaFramboise, WM Lin, ...
Nature genetics 39 (3), 347-351, 2007
11592007
Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma
TF Cloughesy, AY Mochizuki, JR Orpilla, W Hugo, AH Lee, TB Davidson, ...
Nature medicine 25 (3), 477-486, 2019
10842019
Intertumoral heterogeneity within medulloblastoma subgroups
FMG Cavalli, M Remke, L Rampasek, J Peacock, DJH Shih, B Luu, ...
Cancer cell 31 (6), 737-754. e6, 2017
10372017
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ...
Nature 488 (7409), 49-56, 2012
9582012
The whole-genome landscape of medulloblastoma subtypes
PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ...
Nature 547 (7663), 311-317, 2017
9472017
Gene expression profiling of gliomas strongly predicts survival
WA Freije, FE Castro-Vargas, Z Fang, S Horvath, T Cloughesy, LM Liau, ...
Cancer research 64 (18), 6503-6510, 2004
8822004
Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target
S Horvath, B Zhang, M Carlson, KV Lu, S Zhu, RM Felciano, MF Laurance, ...
Proceedings of the National Academy of Sciences 103 (46), 17402-17407, 2006
7422006
Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma
TF Cloughesy, K Yoshimoto, P Nghiemphu, K Brown, J Dang, S Zhu, ...
PLoS medicine 5 (1), e8, 2008
6632008
Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment
LM Liau, RM Prins, SM Kiertscher, SK Odesa, TJ Kremen, AJ Giovannone, ...
Clinical Cancer Research 11 (15), 5515-5525, 2005
6222005
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme
A Lai, A Tran, PL Nghiemphu, WB Pope, OE Solis, M Selch, E Filka, ...
Journal of clinical oncology 29 (2), 142, 2011
5612011
Imaging proliferation in brain tumors with 18F-FLT PET: comparison with 18F-FDG
W Chen, T Cloughesy, N Kamdar, N Satyamurthy, M Bergsneider, L Liau, ...
Journal of Nuclear Medicine 46 (6), 945-952, 2005
5542005
First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma
LM Liau, K Ashkan, DD Tran, JL Campian, JE Trusheim, CS Cobbs, ...
Journal of translational medicine 16, 1-9, 2018
5312018
Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin
A Lai, S Kharbanda, WB Pope, A Tran, OE Solis, F Peale, WF Forrest, ...
Journal of clinical oncology 29 (34), 4482, 2011
5242011
Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy
RM Prins, H Soto, V Konkankit, SK Odesa, A Eskin, WH Yong, SF Nelson, ...
Clinical cancer research 17 (6), 1603-1615, 2011
5122011
Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma
N Zhukova, V Ramaswamy, M Remke, E Pfaff, DJH Shih, DC Martin, ...
Journal of Clinical Oncology 31 (23), 2927, 2013
5062013
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation
LGT Morris, AM Kaufman, Y Gong, D Ramaswami, LA Walsh, Ş Turcan, ...
Nature genetics 45 (3), 253-261, 2013
4312013
Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies
S Veeriah, BS Taylor, S Meng, F Fang, E Yilmaz, I Vivanco, ...
Nature genetics 42 (1), 77-82, 2010
4132010
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Artikler 1–20