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Shengdong Ke
Shengdong Ke
Lab Head, Ke Laborartory
Verified email at caa.columbia.edu - Homepage
Title
Cited by
Cited by
Year
A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
S Ke, EA Alemu, C Mertens, EC Gantman, JJ Fak, A Mele, B Haripal, ...
Genes & development 29 (19), 2037-2053, 2015
7332015
m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover
S Ke, A Pandya-Jones, Y Saito, JJ Fak, CB Vågbø, S Geula, JH Hanna, ...
Genes & development 31 (10), 990-1006, 2017
4972017
Activated Expression of an Arabidopsis HD-START Protein Confers Drought Tolerance with Improved Root System and Reduced Stomatal Density
H Yu, X Chen, YY Hong, Y Wang, P Xu, SD Ke, HY Liu, JK Zhu, DJ Oliver, ...
The Plant Cell 20 (4), 1134-1151, 2008
4032008
Quantitative evaluation of all hexamers as exonic splicing elements
S Ke, S Shang, SM Kalachikov, I Morozova, L Yu, JJ Russo, J Ju, ...
Genome research 21 (8), 1360-1374, 2011
2272011
Pre-mRNA processing includes N6 methylation of adenosine residues that are retained in mRNA exons and the fallacy of “RNA epigenetics”
RB Darnell, S Ke, JE Darnell
Rna 24 (3), 262-267, 2018
842018
Positive selection acting on splicing motifs reflects compensatory evolution
S Ke, XHF Zhang, LA Chasin
Genome Research 18 (4), 533-543, 2008
622008
Saturation mutagenesis reveals manifold determinants of exon definition
S Ke, V Anquetil, JR Zamalloa, A Maity, A Yang, MA Arias, S Kalachikov, ...
Genome research 28 (1), 11-24, 2018
592018
Splicing of designer exons reveals unexpected complexity in pre-mRNA splicing
XHF Zhang, MA Arias, S Ke, LA Chasin
Rna 15 (3), 367-376, 2009
592009
Intronic motif pairs cooperate across exons to promote pre-mRNA splicing
S Ke, LA Chasin
Genome Biology 11, 1-18, 2010
342010
Context-dependent splicing regulation: exon definition, co-occurring motif pairs and tissue specificity
S Ke, LA Chasin
RNA biology 8 (3), 384-388, 2011
292011
Deep learning modeling m6A deposition reveals the importance of downstream cis-element sequences
Z Luo, J Zhang, J Fei, S Ke
Nature communications 13 (1), 2720, 2022
142022
Exon-intron boundary inhibits m6A deposition, enabling m6A distribution hallmark, longer mRNA half-life and flexible protein coding
Z Luo, Q Ma, S Sun, N Li, H Wang, Z Ying, S Ke
Nature Communications 14 (1), 4172, 2023
62023
Splicing by cell type
MA Arias, S Ke, LA Chasin
Nature biotechnology 28 (7), 686-687, 2010
62010
Quantitative Total Definition of Biologically Active Sequence Elements and Positions
LA Chasin, S Ke
US Patent App. 13/776,696, 2013
32013
Quantitative Total Definition of Biologically Active Sequence Elements
LA Chasin, S Ke
US Patent App. 13/818,777, 2013
12013
Pre-mRNA splicing inhibits m6A deposition, allowing longer mRNA half-life and flexible protein coding
Z Luo, Q Ma, S Sun, N Li, H Wang, Z Ying, S Ke
bioRxiv, 2022.12. 26.521933, 2022
2022
Saturation mutagenesis of a human exon
S Ke, LA Chasin
Intergrative RNA Biology Special Interest Group Meeting, 11, 2014
2014
Human pseudo exons,~ 92000
LA Chasin, S Ke, A Wang
2007
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