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Simona Cristea
Simona Cristea
Other namesSimona Constantinescu
Faculty at Dana-Farber Cancer Institute, Research Scientists at Harvard School of Public Health
Verified email at jimmy.harvard.edu - Homepage
Title
Cited by
Cited by
Year
Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq
M Karaayvaz, S Cristea, SM Gillespie, AP Patel, R Mylvaganam, CC Luo, ...
Nature communications 9 (1), 3588, 2018
4072018
Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments
M Janiszewska, DP Tabassum, Z Castaño, S Cristea, KN Yamamoto, ...
Nature cell biology 21 (7), 879-888, 2019
1372019
TiMEx: a waiting time model for mutually exclusive cancer alterations
S Constantinescu, E Szczurek, P Mohammadi, J Rahnenführer, ...
Bioinformatics 32 (7), 968-975, 2016
802016
Chromosomal alterations and gene expression changes associated with the progression of leukoplakia to advanced gingivobuccal cancer
PG Bhosale, S Cristea, S Ambatipudi, RS Desai, R Kumar, A Patil, S Kane, ...
Translational Oncology 10 (3), 396-409, 2017
712017
Dissecting the mammary gland one cell at a time
S Cristea, K Polyak
Nature communications 9 (1), 2473, 2018
662018
Physical and molecular landscapes of mouse glioma extracellular vesicles define heterogeneity
A Gyuris, J Navarrete-Perea, A Jo, S Cristea, S Zhou, K Fraser, Z Wei, ...
Cell reports 27 (13), 3972-3987. e6, 2019
572019
Simultaneous integration of multi-omics data improves the identification of cancer driver modules
D Silverbush, S Cristea, G Yanovich-Arad, T Geiger, N Beerenwinkel, ...
Cell systems 8 (5), 456-466. e5, 2019
55*2019
Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ
L Ding, Y Su, A Fassl, K Hinohara, X Qiu, NW Harper, SJ Huh, ...
Nature communications 10 (1), 4182, 2019
502019
pathTiMEx: Joint Inference of Mutually Exclusive Cancer Pathways and Their Progression Dynamics
S Cristea, J Kuipers, N Beerenwinkel
Journal of Computational Biology 24 (6), 603-615, 2017
402017
Functional Analysis Identifies Damaging CHEK2 Missense Variants Associated with Increased Cancer Risk
RACM Boonen, WW Wiegant, N Celosse, B Vroling, S Heijl, Z Kote-Jarai, ...
Cancer Research 82 (4), 615-631, 2022
382022
The impact of tumor epithelial and microenvironmental heterogeneity on treatment responses in HER2+ breast cancer
M Janiszewska, S Stein, O Metzger Filho, J Eng, NL Kingston, NW Harper, ...
JCI insight 6 (11), 2021
372021
Sulforaphane preconditioning sensitizes human colon cancer cells towards the bioreductive anticancer prodrug PR-104A
MM Erzinger, C Bovet, KM Hecht, S Senger, P Winiker, N Sobotzki, ...
PLoS One 11 (3), e0150219, 2016
252016
Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells
M Yagi, F Ji, J Charlton, S Cristea, K Messemer, N Horwitz, B Di Stefano, ...
Genes & Development 35 (17-18), 1209-1228, 2021
212021
Ectopic expression of Msx2 in mammalian myotubes recapitulates aspects of amphibian muscle dedifferentiation
A Yilmaz, R Engeler, S Constantinescu, KD Kokkaliaris, ...
Stem cell research 15 (3), 542-553, 2015
192015
Transcriptomic responses of cancerous and noncancerous human colon cells to sulforaphane and selenium
S Constantinescu, K Hecht, N Sobotzki, MM Erzinger, C Bovet, JW Shay, ...
Chemical research in toxicology 27 (3), 377-386, 2014
142014
A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression
Z Chen, B Giotti, M Kaluzova, MP Vallcorba, K Rawat, G Price, CJ Herting, ...
The Journal of Clinical Investigation 133 (22), 2023
13*2023
Recurring amplification at 11q22. 1-q22. 2 locus plays an important role in lymph node metastasis and radioresistance in OSCC
PG Bhosale, M Pandey, S Cristea, M Shah, A Patil, N Beerenwinkel, ...
Scientific reports 7 (1), 16051, 2017
132017
Graph-based decomposition of biochemical reaction networks into monotone subsystems
HM Kaltenbach, S Constantinescu, J Feigelman, J Stelling
Algorithms in Bioinformatics: 11th International Workshop, WABI 2011 …, 2011
112011
Single-cell heterogeneity of EGFR and CDK4 co-amplification is linked to immune infiltration in glioblastoma
KA Walentynowicz, D Engelhardt, S Cristea, S Yadav, U Onubogu, ...
Cell reports 42 (3), 2023
102023
H3K36 methylation maintains cell identity by regulating opposing lineage programmes
MS Hoetker, M Yagi, B Di Stefano, J Langerman, S Cristea, LP Wong, ...
Nature cell biology 25 (8), 1121-1134, 2023
72023
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