Gregory Vladimer
Gregory Vladimer
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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
P Duewell, H Kono, KJ Rayner, CM Sirois, G Vladimer, FG Bauernfeind, ...
Nature 464 (7293), 1357-1361, 2010
Somatic mutations of calreticulin in myeloproliferative neoplasms
T Klampfl, H Gisslinger, AS Harutyunyan, H Nivarthi, E Rumi, JD Milosevic, ...
New England Journal of Medicine 369 (25), 2379-2390, 2013
The NLRP12 inflammasome recognizes Yersinia pestis
GI Vladimer, D Weng, SWM Paquette, SK Vanaja, VAK Rathinam, ...
Immunity 37 (1), 96-107, 2012
Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death
D Weng, R Marty-Roix, S Ganesan, MK Proulx, GI Vladimer, WJ Kaiser, ...
Proceedings of the National Academy of Sciences 111 (20), 7391-7396, 2014
Inflammasomes and host defenses against bacterial infections
GI Vladimer, R Marty-Roix, S Ghosh, D Weng, E Lien
Current opinion in microbiology 16 (1), 23-31, 2013
A conserved circular network of coregulated lipids modulates innate immune responses
MS Köberlin, B Snijder, LX Heinz, CL Baumann, A Fauster, GI Vladimer, ...
Cell 162 (1), 170-183, 2015
Identification of QS-21 as an inflammasome-activating molecular component of saponin adjuvants
R Marty-Roix, GI Vladimer, K Pouliot, D Weng, R Buglione-Corbett, ...
Journal of Biological Chemistry 291 (3), 1123-1136, 2016
Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study
B Snijder, GI Vladimer, N Krall, K Miura, AS Schmolke, C Kornauth, ...
The Lancet Haematology 4 (12), e595-e606, 2017
Biallelic loss-of-function mutation in NIK causes a primary immunodeficiency with multifaceted aberrant lymphoid immunity
KL Willmann, S Klaver, F Doğu, E Santos-Valente, W Garncarz, I Bilic, ...
Nature communications 5 (1), 1-13, 2014
A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling
NJ Nilsen, GI Vladimer, J Stenvik, MPA Orning, MV Zeid-Kilani, M Bugge, ...
Journal of Biological Chemistry 290 (6), 3209-3222, 2015
LZTR1 is a regulator of RAS ubiquitination and signaling
JW Bigenzahn, GM Collu, F Kartnig, M Pieraks, GI Vladimer, LX Heinz, ...
Science 362 (6419), 1171-1177, 2018
Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions
P Valent, A Orazi, MR Savona, MM Patnaik, F Onida, ...
haematologica 104 (10), 1935, 2019
IFITs: emerging roles as key anti-viral proteins
GI Vladimer, MW Górna, G Superti-Furga
Frontiers in immunology 5, 94, 2014
The RNA‐binding protein HuR/ELAVL1 regulates IFN‐β mRNA abundance and the type I IFN response
B Herdy, T Karonitsch, GI Vladimer, CSH Tan, A Stukalov, C Trefzer, ...
European Journal of Immunology 45 (5), 1500-1511, 2015
Global survey of the immunomodulatory potential of common drugs
GI Vladimer, B Snijder, N Krall, JW Bigenzahn, KVM Huber, CH Lardeau, ...
Nature chemical biology 13 (6), 681-690, 2017
Gadolinium-based compounds induce NLRP3-dependent IL-1β production and peritoneal inflammation
C Schmidt-Lauber, L Bossaller, HH Abujudeh, GI Vladimer, A Christ, ...
Annals of the rheumatic diseases 74 (11), 2062-2069, 2015
A time-resolved molecular map of the macrophage response to VSV infection
RK Kandasamy, GI Vladimer, B Snijder, AC Müller, M Rebsamen, ...
NPJ systems biology and applications 2 (1), 1-12, 2016
An inducible retroviral expression system for tandem affinity purification mass-spectrometry-based proteomics identifies mixed lineage kinase domain-like protein (MLKL) as an …
JW Bigenzahn, A Fauster, M Rebsamen, RK Kandasamy, S Scorzoni, ...
Molecular & Cellular Proteomics 15 (3), 1139-1150, 2016
Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL
C Schmidl, GI Vladimer, AF Rendeiro, S Schnabl, T Krausgruber, ...
Nature chemical biology 15 (3), 232-240, 2019
FOXO3 is involved in the tumor necrosis factor-driven inflammatory response in fibroblast-like synoviocytes
B Brandstetter, K Dalwigk, A Platzer, B Niederreiter, F Kartnig, A Fischer, ...
Laboratory Investigation 99 (5), 648-658, 2019
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