| ID-Score: a new empirical scoring function based on a comprehensive set of descriptors related to protein–ligand interactions GB Li, LL Yang, WJ Wang, LL Li, SY Yang Journal of chemical information and modeling 53 (3), 592-600, 2013 | 205 | 2013 |
| New techniques and strategies in drug discovery J Du, J Guo, D Kang, Z Li, G Wang, J Wu, Z Zhang, H Fang, X Hou, ... Chinese Chemical Letters 31 (7), 1695-1708, 2020 | 107 | 2020 |
| Heterocyclic-fused pyrimidines as novel tubulin polymerization inhibitors targeting the colchicine binding site: structural basis and antitumor efficacy S Banerjee, KE Arnst, Y Wang, G Kumar, S Deng, L Yang, G Li, J Yang, ... Journal of medicinal chemistry 61 (4), 1704-1718, 2018 | 106 | 2018 |
| Annexin A2 binds to endosomes and negatively regulates TLR4-triggered inflammatory responses via the TRAM-TRIF pathway S Zhang, M Yu, Q Guo, R Li, G Li, S Tan, X Li, Y Wei, M Wu Scientific reports 5 (1), 15859, 2015 | 96 | 2015 |
| NMR-filtered virtual screening leads to non-metal chelating metallo-β-lactamase inhibitors GB Li, MI Abboud, J Brem, H Someya, CT Lohans, SY Yang, J Spencer, ... Chemical Science 8 (2), 928-937, 2017 | 79 | 2017 |
| Mechanism of microtubule stabilization by taccalonolide AJ Y Wang, Y Yu, GB Li, SA Li, C Wu, B Gigant, W Qin, H Chen, Y Wu, ... Nature communications 8 (1), 15787, 2017 | 77 | 2017 |
| Real-time bioluminescence imaging of nitroreductase in mouse model P Feng, H Zhang, Q Deng, W Liu, L Yang, G Li, G Chen, L Du, B Ke, M Li Analytical chemistry 88 (11), 5610-5614, 2016 | 77 | 2016 |
| Sirtuin 5: a review of structure, known inhibitors and clues for developing new inhibitors L Yang, X Ma, Y He, C Yuan, Q Chen, G Li, X Chen Science China Life Sciences 60, 249-256, 2017 | 71 | 2017 |
| Structure–Activity Relationship Studies of Pyrazolo[3,4-d]pyrimidine Derivatives Leading to the Discovery of a Novel Multikinase Inhibitor That Potently Inhibits FLT3 … LL Yang, GB Li, S Ma, C Zou, S Zhou, QZ Sun, C Cheng, X Chen, ... Journal of medicinal chemistry 56 (4), 1641-1655, 2013 | 68 | 2013 |
| Activation of AMPK by triptolide alleviates nonalcoholic fatty liver disease by improving hepatic lipid metabolism, inflammation and fibrosis R Huang, F Guo, Y Li, Y Liang, G Li, P Fu, L Ma Phytomedicine 92, 153739, 2021 | 61 | 2021 |
| Discovery of N6-phenyl-1H-pyrazolo [3, 4-d] pyrimidine-3, 6-diamine derivatives as novel CK1 inhibitors using common-feature pharmacophore model based virtual screening and hit … LL Yang, GB Li, HX Yan, QZ Sun, S Ma, P Ji, ZR Wang, S Feng, J Zou, ... European journal of medicinal chemistry 56, 30-38, 2012 | 58 | 2012 |
| ((S)-3-Mercapto-2-methylpropanamido) acetic acid derivatives as metallo-β-lactamase inhibitors: synthesis, kinetic and crystallographic studies S Liu, L Jing, ZJ Yu, C Wu, Y Zheng, E Zhang, Q Chen, Y Yu, L Guo, Y Wu, ... European Journal of Medicinal Chemistry 145, 649-660, 2018 | 55 | 2018 |
| Visible light photoredox catalyzed thiophosphate synthesis using methylene blue as a promoter H Zhang, Z Zhan, Y Lin, Y Shi, G Li, Q Wang, Y Deng, L Hai, Y Wu Organic Chemistry Frontiers 5 (9), 1416-1422, 2018 | 53 | 2018 |
| Discovery and preliminary structure–activity relationship of 1H-indazoles with promising indoleamine-2, 3-dioxygenase 1 (IDO1) inhibition properties S Qian, T He, W Wang, Y He, M Zhang, L Yang, G Li, Z Wang Bioorganic & Medicinal Chemistry 24 (23), 6194-6205, 2016 | 51 | 2016 |
| Design, Synthesis, and Structure–Activity Relationship Studies of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as a New Class of Src … CH Zhang, MW Zheng, YP Li, XD Lin, M Huang, L Zhong, GB Li, ... Journal of medicinal chemistry 58 (9), 3957-3974, 2015 | 51 | 2015 |
| Deep learning in target prediction and drug repositioning: Recent advances and challenges JL Yu, QQ Dai, GB Li Drug Discovery Today 27 (7), 1796-1814, 2022 | 50 | 2022 |
| Structure-based development of (1-(3′-mercaptopropanamido) methyl) boronic acid derived broad-spectrum, dual-action inhibitors of metallo-and serine-β-lactamases YL Wang, S Liu, ZJ Yu, Y Lei, MY Huang, YH Yan, Q Ma, Y Zheng, ... Journal of Medicinal Chemistry 62 (15), 7160-7184, 2019 | 50 | 2019 |
| X-ray crystal structure guided discovery of new selective, substrate-mimicking sirtuin 2 inhibitors that exhibit activities against non-small cell lung cancer cells LL Yang, HL Wang, L Zhong, C Yuan, SY Liu, ZJ Yu, S Liu, YH Yan, C Wu, ... European journal of medicinal chemistry 155, 806-823, 2018 | 50 | 2018 |
| Principles and current strategies targeting metallo‐β‐lactamase mediated antibacterial resistance YH Yan, G Li, GB Li Medicinal Research Reviews 40 (5), 1558-1592, 2020 | 49 | 2020 |
| Discovery of 2-((4, 6-dimethylpyrimidin-2-yl) thio)-N-phenylacetamide derivatives as new potent and selective human sirtuin 2 inhibitors L Yang, X Ma, C Yuan, Y He, L Li, S Fang, W Xia, T He, S Qian, Z Xu, G Li, ... European Journal of Medicinal Chemistry 134, 230-241, 2017 | 44 | 2017 |
qiang chenpeking university, dana-farber cancer institute, sichuan universityVerified email at dfci.harvard.edu
