| Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease T Guo, D Zhang, Y Zeng, TY Huang, H Xu, Y Zhao Molecular neurodegeneration 15, 1-37, 2020 | 562 | 2020 |
| TREM2 is a receptor for β-amyloid that mediates microglial function Y Zhao, X Wu, X Li, LL Jiang, X Gui, Y Liu, Y Sun, B Zhu, JC Piña-Crespo, ... Neuron 97 (5), 1023-1031. e7, 2018 | 555 | 2018 |
| Cofilin phosphatases and regulation of actin dynamics TY Huang, C DerMardirossian, GM Bokoch Current opinion in cell biology 18 (1), 26-31, 2006 | 439 | 2006 |
| Dysregulation of ubiquitin-proteasome system in neurodegenerative diseases Q Zheng, T Huang, L Zhang, Y Zhou, H Luo, H Xu, X Wang Frontiers in aging neuroscience 8, 303, 2016 | 279 | 2016 |
| Reactive oxygen species regulate a slingshot-cofilin activation pathway JS Kim, TY Huang, GM Bokoch Molecular biology of the cell 20 (11), 2650-2660, 2009 | 232 | 2009 |
| Menin deficiency leads to depressive-like behaviors in mice by modulating astrocyte-mediated neuroinflammation L Leng, K Zhuang, Z Liu, C Huang, Y Gao, G Chen, H Lin, Y Hu, D Wu, ... Neuron 100 (3), 551-563. e7, 2018 | 170 | 2018 |
| Dysregulation of protein trafficking in neurodegeneration X Wang, T Huang, G Bu, H Xu Molecular neurodegeneration 9, 1-9, 2014 | 137 | 2014 |
| Pnk1, a DNA kinase/phosphatase required for normal response to DNA damage by γ-radiation or camptothecin inSchizosaccharomyces pombe M Meijer, F Karimi-Busheri, TY Huang, M Weinfeld, D Young Journal of Biological Chemistry 277 (6), 4050-4055, 2002 | 127 | 2002 |
| Chronophin mediates an ATP-sensing mechanism for cofilin dephosphorylation and neuronal cofilin-actin rod formation TY Huang, LS Minamide, JR Bamburg, GM Bokoch Developmental cell 15 (5), 691-703, 2008 | 120 | 2008 |
| Appoptosin-mediated caspase cleavage of tau contributes to progressive supranuclear palsy pathogenesis Y Zhao, IC Tseng, CJ Heyser, E Rockenstein, M Mante, A Adame, ... Neuron 87 (5), 963-975, 2015 | 102 | 2015 |
| Amyloid, tau, pathogen infection and antimicrobial protection in Alzheimer’s disease–conformist, nonconformist, and realistic prospects for AD pathogenesis H Li, CC Liu, H Zheng, TY Huang Translational neurodegeneration 7, 1-16, 2018 | 100 | 2018 |
| β-Arrestins scaffold cofilin with chronophin to direct localized actin filament severing and membrane protrusions downstream of protease-activated receptor-2 M Zoudilova, J Min, HL Richards, D Carter, T Huang, KA DeFea Journal of biological chemistry 285 (19), 14318-14329, 2010 | 94 | 2010 |
| Isolation and characterization of cytoplasmic cofilin-actin rods LS Minamide, S Maiti, JA Boyle, RC Davis, JA Coppinger, Y Bao, ... Journal of biological chemistry 285 (8), 5450-5460, 2010 | 86 | 2010 |
| The retromer complex and sorting nexins in neurodegenerative diseases H Zhang, T Huang, Y Hong, W Yang, X Zhang, H Luo, H Xu, X Wang Frontiers in aging neuroscience 10, 79, 2018 | 81 | 2018 |
| Sorting nexin 27 regulates Aβ production through modulating γ-secretase activity X Wang, T Huang, Y Zhao, Q Zheng, RC Thompson, G Bu, Y Zhang, ... Cell reports 9 (3), 1023-1033, 2014 | 76 | 2014 |
| Apoptotic stress causes mtDNA release during senescence and drives the SASP S Victorelli, H Salmonowicz, J Chapman, H Martini, MG Vizioli, JS Riley, ... Nature 622 (7983), 627-636, 2023 | 58 | 2023 |
| SNX27 and SORLA interact to reduce amyloidogenic subcellular distribution and processing of amyloid precursor protein TY Huang, Y Zhao, X Li, X Wang, IC Tseng, R Thompson, S Tu, ... Journal of Neuroscience 36 (30), 7996-8011, 2016 | 58 | 2016 |
| ER-associated degradation regulates Alzheimer’s amyloid pathology and memory function by modulating γ-secretase activity B Zhu, LL Jiang, T Huang, Y Zhao, T Liu, Y Zhong, X Li, A Campos, ... Nature Communications 8 (1), 1472, 2017 | 56 | 2017 |
| Inhibition of PKCδ reduces amyloid-β levels and reverses Alzheimer disease phenotypes Y Du, Y Zhao, C Li, Q Zheng, J Tian, Z Li, TY Huang, W Zhang, H Xu Journal of Experimental Medicine 215 (6), 1665-1677, 2018 | 54 | 2018 |
| SORLA attenuates EphA4 signaling and amyloid β–induced neurodegeneration TY Huang, Y Zhao, L Jiang, X Li, Y Liu, Y Sun, JC Piña-Crespo, B Zhu, ... Journal of Experimental Medicine 214 (12), 3669-3685, 2017 | 44 | 2017 |
