| RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V (D) J rearrangement Y Shinkai, KP Lam, EM Oltz, V Stewart, M Mendelsohn, J Charron, ... Cell 68 (5), 855-867, 1992 | 3411 | 1992 |
| Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta S Giroux, M Tremblay, D Bernard, JF Cardin-Girard, S Aubry, L Larouche, ... Current Biology 9 (7), 369-376, 1999 | 466 | 1999 |
| Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene. J Charron, BA Malynn, P Fisher, V Stewart, L Jeannotte, SP Goff, ... Genes & development 6 (12a), 2248-2257, 1992 | 415 | 1992 |
| c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma RB Blasco, S Francoz, D Santamaría, M Canamero, P Dubus, J Charron, ... Cancer cell 19 (5), 652-663, 2011 | 333 | 2011 |
| Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells J Choi, AJ Huebner, K Clement, RM Walsh, A Savol, K Lin, H Gu, ... Nature 548 (7666), 219-223, 2017 | 251 | 2017 |
| Mek2 Is Dispensable for Mouse Growth and Development LF Bélanger, S Roy, M Tremblay, B Brott, AM Steff, W Mourad, P Hugo, ... Molecular and cellular biology 23 (14), 4778-4787, 2003 | 244 | 2003 |
| Structure of the rat pro‐opiomelanocortin (POMC) gene J Drouin, M Chamberland, J Charron, L Jeannotte, M Nemer FEBS letters 193 (1), 54-58, 1985 | 232 | 1985 |
| Specification of axial identity in the mouse: role of the Hoxa-5 (Hox1. 3) gene. L Jeannotte, M Lemieux, J Charron, F Poirier, EJ Robertson Genes & development 7 (11), 2085-2096, 1993 | 223 | 1993 |
| Role of Plk2 (Snk) in Mouse Development and Cell Proliferation S Ma, J Charron, RL Erikson Molecular and cellular biology 23 (19), 6936-6943, 2003 | 208 | 2003 |
| Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development J Newbern, J Zhong, RS Wickramasinghe, X Li, Y Wu, I Samuels, ... Proceedings of the National Academy of Sciences 105 (44), 17115-17120, 2008 | 193 | 2008 |
| Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia FA Scholl, PA Dumesic, DI Barragan, K Harada, V Bissonauth, J Charron, ... Developmental cell 12 (4), 615-629, 2007 | 178 | 2007 |
| MEK is a key regulator of gliogenesis in the developing brain X Li, JM Newbern, Y Wu, M Morgan-Smith, J Zhong, J Charron, ... Neuron 75 (6), 1035-1050, 2012 | 169 | 2012 |
| Phosphorylation is involved in the activation of metal-regulatory transcription factor 1 in response to metal ions O LaRochelle, V Gagné, J Charron, JW Soh, C Séguin Journal of Biological Chemistry 276 (45), 41879-41888, 2001 | 148 | 2001 |
| Activated MEK Suppresses Activation of PKR and Enables Efficient Replication and In Vivo Oncolysis by Δγ134.5 Mutants of Herpes Simplex Virus 1 KD Smith, JJ Mezhir, K Bickenbach, J Veerapong, J Charron, MC Posner, ... Journal of virology 80 (3), 1110-1120, 2006 | 139 | 2006 |
| Pro‐opiomelanocortin gene: A model for negative regulation of transcription by glucocorticoids J Drouin, J Charron, JP Gagner, L Jeannotte, M Nemer, RK Plante, ... Journal of cellular biochemistry 35 (4), 293-304, 1987 | 130 | 1987 |
| Glucocorticoid inhibition of transcription from episomal proopiomelanocortin gene promoter. J Charron, J Drouin Proceedings of the National Academy of Sciences 83 (23), 8903-8907, 1986 | 127 | 1986 |
| B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS KJ O’Donovan, K Ma, H Guo, C Wang, F Sun, SB Han, H Kim, JK Wong, ... Journal of Experimental Medicine 211 (5), 801-814, 2014 | 111 | 2014 |
| Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis V Bissonauth, S Roy, M Gravel, S Guillemette, J Charron Oxford University Press for The Company of Biologists Limited 133 (17), 3429 …, 2006 | 98 | 2006 |
| High-frequency disruption of the N-myc gene in embryonic stem and pre-B cell lines by homologous recombination J Charron, BA Malynn, EJ Robertson, SP Goff, FW Alt Molecular and cellular biology, 1990 | 87 | 1990 |
| The Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertility S Yamashita, P Tai, J Charron, CM Ko, M Ascoli Molecular endocrinology 25 (7), 1211-1222, 2011 | 78 | 2011 |
