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Jacob Lemieux
Jacob Lemieux
The Broad Institute
Verifisert e-postadresse på broadinstitute.org
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CCR2 modulates inflammatory and metabolic effects of high-fat feeding
SP Weisberg, D Hunter, R Huber, J Lemieux, S Slaymaker, K Vaddi, ...
The Journal of clinical investigation 116 (1), 115-124, 2006
20252006
Structural and functional analysis of the D614G SARS-CoV-2 spike protein variant
L Yurkovetskiy, X Wang, KE Pascal, C Tomkins-Tinch, TP Nyalile, Y Wang, ...
Cell 183 (3), 739-751. e8, 2020
10162020
Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome
AP Hsu, EP Sampaio, J Khan, KR Calvo, JE Lemieux, SY Patel, ...
Blood, The Journal of the American Society of Hematology 118 (10), 2653-2655, 2011
6692011
New insights into the blood‐stage transcriptome of Plasmodium falciparum using RNA‐Seq
TD Otto, D Wilinski, S Assefa, TM Keane, LR Sarry, U Böhme, J Lemieux, ...
Molecular microbiology 76 (1), 12-24, 2010
4432010
Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum
MJ López-Barragán, J Lemieux, M Quiñones, KC Williamson, ...
BMC genomics 12, 1-13, 2011
3482011
Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2
J Arizti-Sanz, CA Freije, AC Stanton, BA Petros, CK Boehm, S Siddiqui, ...
Nature communications 11 (1), 5921, 2020
2972020
GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome
AP Hsu, KD Johnson, EL Falcone, R Sanalkumar, L Sanchez, ...
Blood, The Journal of the American Society of Hematology 121 (19), 3830-3837, 2013
2732013
Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events
JE Lemieux, KJ Siddle, BM Shaw, C Loreth, SF Schaffner, ...
Science 371 (6529), eabe3261, 2021
2542021
Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness
F Obermeyer, M Jankowiak, N Barkas, SF Schaffner, JD Pyle, ...
Science 376 (6599), 1327-1332, 2022
1802022
Comparative transmissibility of SARS-CoV-2 variants delta and alpha in New England, USA
R Earnest, R Uddin, N Matluk, N Renzette, SE Turbett, KJ Siddle, C Loreth, ...
Cell Reports Medicine 3 (4), 2022
1552022
Duration of shedding of culturable virus in SARS-CoV-2 Omicron (BA. 1) infection
J Boucau, C Marino, J Regan, R Uddin, MC Choudhary, JP Flynn, G Chen, ...
New England Journal of Medicine 387 (3), 275-277, 2022
1372022
Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants
NL Welch, M Zhu, C Hua, J Weller, ME Mirhashemi, TG Nguyen, ...
Nature Medicine 28 (5), 1083-1094, 2022
1362022
Defining the risk of SARS-CoV-2 variants on immune protection
MM DeGrace, E Ghedin, MB Frieman, F Krammer, A Grifoni, A Alisoltani, ...
Nature 605 (7911), 640-652, 2022
1332022
Lyme disease in humans
JD Radolf, K Strle, JE Lemieux, F Strle
Current issues in molecular biology 42 (1), 333-384, 2021
1012021
Statistical estimation of cell-cycle progression and lineage commitment in Plasmodium falciparum reveals a homogeneous pattern of transcription in ex vivo culture
JE Lemieux, N Gomez-Escobar, A Feller, C Carret, A Amambua-Ngwa, ...
Proceedings of the National Academy of Sciences 106 (18), 7559-7564, 2009
972009
A global map of genetic diversity in Babesia microti reveals strong population structure and identifies variants associated with clinical relapse
JE Lemieux, AD Tran, L Freimark, SF Schaffner, H Goethert, KG Andersen, ...
Nature microbiology 1 (7), 1-7, 2016
872016
SARS-CoV-2 Spike protein variant D614G increases infectivity and retains sensitivity to antibodies that target the receptor binding domain
L Yurkovetskiy, KE Pascal, C Tomkins-Tinch, T Nyalile, Y Wang, A Baum, ...
BioRxiv, 2020.07. 04.187757, 2020
822020
Susceptibility-weighted imaging reveals cerebral microvascular injury in severe COVID-19
J Conklin, MP Frosch, SS Mukerji, O Rapalino, MD Maher, PW Schaefer, ...
Journal of the neurological sciences 421, 117308, 2021
742021
Characterization of virologic rebound following nirmatrelvir-ritonavir treatment for coronavirus disease 2019 (COVID-19)
J Boucau, R Uddin, C Marino, J Regan, JP Flynn, MC Choudhary, G Chen, ...
Clinical Infectious Diseases 76 (3), e526-e529, 2023
732023
Genome‐wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic …
JE Lemieux, SA Kyes, TD Otto, AI Feller, RT Eastman, RA Pinches, ...
Molecular microbiology 90 (3), 519-537, 2013
582013
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Artikler 1–20