Melodie Christensen
Melodie Christensen
Verified email at merck.com
Title
Cited by
Cited by
Year
Selective Hydrogen Atom Abstraction through Induced Bond Polarization: Direct α‐Arylation of Alcohols through Photoredox, HAT, and Nickel Catalysis
J Twilton, M Christensen, DA DiRocco, RT Ruck, IW Davies, ...
Angewandte Chemie 130 (19), 5467-5471, 2018
972018
The evolution of high-throughput experimentation in pharmaceutical development and perspectives on the future
SM Mennen, C Alhambra, CL Allen, M Barberis, S Berritt, TA Brandt, ...
Organic Process Research & Development 23 (6), 1213-1242, 2019
962019
Enantioselective synthesis of an HCV NS5a antagonist
IK Mangion, C Chen, H Li, P Maligres, Y Chen, M Christensen, R Cohen, ...
Organic letters 16 (9), 2310-2313, 2014
582014
Expedited selection of NMR chiral solvating agents for determination of enantiopurity
L Yang, T Wenzel, RT Williamson, M Christensen, W Schafer, CJ Welch
ACS central science 2 (5), 332-340, 2016
402016
Enantioselective Synthesis of α-Methyl-β-cyclopropyldihydrocinnamates
M Christensen, A Nolting, M Shevlin, M Weisel, PE Maligres, J Lee, ...
The Journal of organic chemistry 81 (3), 824-830, 2016
372016
Asymmetric synthesis of letermovir using a novel phase-transfer-catalyzed aza-Michael reaction
GR Humphrey, SM Dalby, T Andreani, B Xiang, MR Luzung, ZJ Song, ...
Organic Process Research & Development 20 (6), 1097-1103, 2016
362016
Discovery of 2-pyridinone aminals: a prodrug strategy to advance a second generation of HIV-1 integrase strand transfer inhibitors
IT Raheem, AM Walji, D Klein, JM Sanders, DA Powell, P Abeywickrema, ...
Journal of medicinal chemistry 58 (20), 8154-8165, 2015
282015
P2Et Phosphazene: A Mild, Functional Group Tolerant Base for Soluble, Room Temperature Pd-Catalyzed C–N, C–O, and C–C Cross-Coupling Reactions
A Buitrago Santanilla, M Christensen, LC Campeau, IW Davies, ...
Organic letters 17 (13), 3370-3373, 2015
222015
Design and synthesis of novel, selective GPR40 AgoPAMs
CW Plummer, MJ Clements, H Chen, M Rajagopalan, H Josien, ...
ACS medicinal chemistry letters 8 (2), 221-226, 2017
202017
P2Et phosphazene: a mild, functional group tolerant base for soluble, room temperature Pd-catalyzed C–N, C–O, and C–C cross-coupling reactions
AB Santanilla, M Christensen, LC Campeau, IW Davies, SD Dreher
Org. Lett 17, 3370-3373, 2015
202015
Metal-and acid-free C–H formylation of nitrogen heterocycles: using trioxane as an aldehyde equivalent enabled by an organic-soluble oxidant
JM Ganley, M Christensen, Y Lam, Z Peng, AR Angeles, CS Yeung
Organic letters 20 (18), 5752-5756, 2018
172018
Selective functionalization of complex heterocycles via an automated strong base screening platform
SB Boga, M Christensen, N Perrotto, SW Krska, S Dreher, MT Tudge, ...
Reaction Chemistry & Engineering 2 (4), 446-450, 2017
162017
Olympus: a benchmarking framework for noisy optimization and experiment planning
F Hase, M Aldeghi, R Hickman, L Roch, E Liles, M Christensen, J Hein, ...
Machine Learning: Science and Technology, 2021
142021
Development of an automated kinetic profiling system with online HPLC for reaction optimization
M Christensen, F Adedeji, S Grosser, K Zawatzky, Y Ji, J Liu, JA Jurica, ...
Reaction Chemistry & Engineering 4 (9), 1555-1558, 2019
132019
Data-science driven autonomous process optimization
M Christensen, LPE Yunker, F Adedeji, F Häse, LM Roch, T Gensch, ...
Communications Chemistry 4 (1), 1-12, 2021
112021
Automation Isn’t Automatic
M Christensen, LPE Yunker, P Shiri, T Zepel, P Prieto, S Grunert, F Bork, ...
Chemical Science, 2021
2021
Process for preparing substituted tetracyclic heterocycle compounds
J Yin, T Itoh, J Yin, B Xiang, KR Campos, A Kalinin, Z Liu, MD Christensen, ...
US Patent 10,457,690, 2019
2019
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Articles 1–17