| TREM2 is a receptor for β-amyloid that mediates microglial function Y Zhao, X Wu, X Li, LL Jiang, X Gui, Y Liu, Y Sun, B Zhu, JC Piña-Crespo, ... Neuron 97 (5), 1023-1031. e7, 2018 | 555 | 2018 |
| Elevated TREM2 gene dosage reprograms microglia responsivity and ameliorates pathological phenotypes in Alzheimer’s disease models CYD Lee, A Daggett, X Gu, LL Jiang, P Langfelder, X Li, N Wang, Y Zhao, ... Neuron 97 (5), 1032-1048. e5, 2018 | 309 | 2018 |
| SNX27 and SORLA interact to reduce amyloidogenic subcellular distribution and processing of amyloid precursor protein TY Huang, Y Zhao, X Li, X Wang, IC Tseng, R Thompson, S Tu, ... Journal of Neuroscience 36 (30), 7996-8011, 2016 | 58 | 2016 |
| ER-associated degradation regulates Alzheimer’s amyloid pathology and memory function by modulating γ-secretase activity B Zhu, LL Jiang, T Huang, Y Zhao, T Liu, Y Zhong, X Li, A Campos, ... Nature Communications 8 (1), 1472, 2017 | 56 | 2017 |
| SORLA attenuates EphA4 signaling and amyloid β–induced neurodegeneration TY Huang, Y Zhao, L Jiang, X Li, Y Liu, Y Sun, JC Piña-Crespo, B Zhu, ... Journal of Experimental Medicine 214 (12), 3669-3685, 2017 | 44 | 2017 |
| Multi-omic comparison of Alzheimer’s variants in human ESC–derived microglia reveals convergence at APOE T Liu, B Zhu, Y Liu, X Zhang, J Yin, X Li, LL Jiang, AP Hodges, ... Journal of Experimental Medicine 217 (12), e20200474, 2020 | 41 | 2020 |
| Membralin deficiency dysregulates astrocytic glutamate homeostasis, leading to ALS-like impairment LL Jiang, B Zhu, Y Zhao, X Li, T Liu, J Pina-Crespo, L Zhou, W Xu, ... The Journal of Clinical Investigation 129 (8), 3103-3120, 2019 | 36 | 2019 |
| Intracellular trafficking of TREM2 is regulated by presenilin 1 Y Zhao, X Li, T Huang, L Jiang, Z Tan, M Zhang, IHJ Cheng, X Wang, ... Experimental & Molecular Medicine 49 (12), e405-e405, 2017 | 25 | 2017 |
| β-asarone mitigates amyloidosis and downregulates RAGE in a transgenic mouse model of Alzheimer’s disease C Yang, X Li, Y Mo, S Liu, L Zhao, X Ma, Z Fang, J Chen, Y Chen, X Yu, ... Cellular and molecular neurobiology 36, 121-130, 2016 | 25 | 2016 |
