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Nicolas Descostes
Nicolas Descostes
Head of Bioinformatics EMBL Rome
Verifisert e-postadresse på embl.it - Startside
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Argonaute proteins couple chromatin silencing to alternative splicing
M Ameyar-Zazoua, C Rachez, M Souidi, P Robin, L Fritsch, R Young, ...
Nature structural & molecular biology 19 (10), 998-1004, 2012
3182012
CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters
R Fenouil, P Cauchy, F Koch, N Descostes, JZ Cabeza, C Innocenti, ...
Genome research 22 (12), 2399-2408, 2012
2602012
Capturing the onset of PRC2-mediated repressive domain formation
O Oksuz, V Narendra, CH Lee, N Descostes, G LeRoy, R Raviram, ...
Molecular Cell 70 (6), 1149-1162. e5, 2018
2372018
Threonine‐4 of mammalian RNA polymerase II CTD is targeted by Polo‐like kinase 3 and required for transcriptional elongation
C Hintermair, M Heidemann, F Koch, N Descostes, M Gut, I Gut, R Fenouil, ...
The EMBO journal 31 (12), 2784-2797, 2012
1832012
Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma
JM Stafford, CH Lee, P Voigt, N Descostes, R Saldaña-Meyer, JR Yu, ...
Science advances 4 (10), eaau5935, 2018
1472018
Active and repressed chromatin domains exhibit distinct nucleosome segregation during DNA replication
TM Escobar, O Oksuz, R Saldaña-Meyer, N Descostes, R Bonasio, ...
Cell 179 (4), 953-963. e11, 2019
1242019
Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells
N Descostes, M Heidemann, L Spinelli, R Schüller, MA Maqbool, ...
Elife 3, e02105, 2014
1102014
LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells
G LeRoy, O Oksuz, N Descostes, Y Aoi, RA Ganai, HO Kara, JR Yu, ...
Science Advances 5 (10), eaay3068, 2019
642019
ARS2 is a general suppressor of pervasive transcription
C Iasillo, M Schmid, Y Yahia, MA Maqbool, N Descostes, E Karadoulama, ...
Nucleic acids research 45 (17), 10229-10241, 2017
552017
Site-specific methylation and acetylation of lysine residues in the C-terminal domain (CTD) of RNA polymerase II
K Voss, I Forné, N Descostes, C Hintermair, R Schüller, MA Maqbool, ...
Transcription 6 (5), 91-101, 2015
352015
NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain
S Liu, KA Aldinger, CV Cheng, T Kiyama, M Dave, HK McNamara, ...
Molecular cell 81 (22), 4663-4676. e8, 2021
322021
Insulin signaling in the long-lived reproductive caste of ants
H Yan, C Opachaloemphan, F Carmona-Aldana, G Mancini, J Mlejnek, ...
Science 377 (6610), 1092-1099, 2022
262022
The H3K36me2 writer-reader dependency in H3K27M-DIPG
JR Yu, G LeRoy, D Bready, JD Frenster, R Saldaña-Meyer, Y Jin, ...
Science Advances 7 (29), eabg7444, 2021
242021
Pasha: a versatile R package for piling chromatin HTS data
R Fenouil, N Descostes, L Spinelli, F Koch, MA Maqbool, T Benoukraf, ...
Bioinformatics 32 (16), 2528-2530, 2016
202016
MIR sequences recruit zinc finger protein ZNF768 to expressed genes
M Rohrmoser, M Kluge, Y Yahia, A Gruber-Eber, MA Maqbool, I Forné, ...
Nucleic acids research 47 (2), 700-715, 2019
182019
Single-cell atlas of major haematopoietic tissues sheds light on blood cell formation from embryonic endothelium
M Shvartsman, PV Pavlovich, M Oatley, K Ganter, R McKernan, ...
bioRxiv, 774547, 2019
42019
Identifying a novel role for the master regulator Tal1 in the Endothelial to Hematopoietic Transition
YN Serina Secanechia, I Bergiers, M Rogon, C Arnold, N Descostes, S Le, ...
Scientific Reports 12 (1), 16974, 2022
22022
ChIPSeqSpike: AR/Bioconductor package for ChIP-Seq data scaling according to spike-in control
N Descostes, A Tsirigos, D Reinberg
bioRxiv, 269118, 2018
12018
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Artikler 1–18