Inversion of extender unit selectivity in the erythromycin polyketide synthase by acyltransferase domain engineering I Koryakina, C Kasey, JB McArthur, AN Lowell, JA Chemler, S Li, ... ACS chemical biology 12 (1), 114-123, 2017 | 77 | 2017 |
Hapalindole/ambiguine biogenesis is mediated by a Cope rearrangement, C–C bond-forming cascade S Li, AN Lowell, F Yu, A Raveh, SA Newmister, N Bair, JM Schaub, ... Journal of the American Chemical Society 137 (49), 15366-15369, 2015 | 70 | 2015 |
High-Affinity Peptidomimetic Inhibitors of the DCN1-UBC12 Protein–Protein Interaction H Zhou, W Zhou, B Zhou, L Liu, TR Chern, K Chinnaswamy, J Lu, ... Journal of medicinal chemistry 61 (5), 1934-1950, 2018 | 54 | 2018 |
Decoding cyclase-dependent assembly of hapalindole and fischerindole alkaloids S Li, AN Lowell, SA Newmister, F Yu, RM Williams, DH Sherman Nature chemical biology 13 (5), 467-469, 2017 | 37 | 2017 |
Design, synthesis and antitumor activity of non-camptothecin topoisomerase I inhibitors C Zhang, S Li, L Ji, S Liu, Z Li, S Li, X Meng Bioorganic & medicinal chemistry letters 25 (20), 4693-4696, 2015 | 35 | 2015 |
Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis SA Newmister, S Li, M Garcia-Borràs, JN Sanders, S Yang, AN Lowell, ... Nature chemical biology 14 (4), 345-351, 2018 | 33 | 2018 |
The novel triazolonaphthalimide derivative LSS-11 synergizes the anti-proliferative effect of paclitaxel via STAT3-dependent MDR1 and MRP1 downregulation in chemoresistant lung … L Ji, X Liu, S Zhang, S Tang, S Yang, S Li, X Qi, S Yu, L Lu, X Meng, Z Liu Molecules 22 (11), 1822, 2017 | 24 | 2017 |
Multicomponent microscale biosynthesis of unnatural cyanobacterial indole alkaloids Y Khatri, RM Hohlman, J Mendoza, S Li, AN Lowell, H Asahara, ... ACS synthetic biology 9 (6), 1349-1360, 2020 | 23 | 2020 |
A novel triazolonaphthalimide induces apoptosis and inhibits tumor growth by targeting DNA and DNA-associated processes L Ji, S Yang, S Li, S Liu, S Tang, Z Liu, X Meng, S Yu Oncotarget 8 (23), 37394, 2017 | 15 | 2017 |
Unprecedented synthesis, in vitro and in vivo anti-cancer evaluation of novel triazolonaphthalimide derivatives S Li, W Zhong, Z Li, X Meng European journal of medicinal chemistry 47, 546-552, 2012 | 14 | 2012 |
Merging late-stage diversification with solid-phase peptide synthesis enabled by high-throughput on-resin reaction screening S Li, D Pissarnitski, T Nowak, M Wleklinski, SW Krska ACS Catalysis 12 (5), 3201-3210, 2022 | 7 | 2022 |
Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan WL Cheung‐Lee, JN Kolev, JA McIntosh, AA Gil, W Pan, L Xiao, ... Angewandte Chemie International Edition, e202316133, 2024 | 6 | 2024 |
Structural Diversification of Hapalindole and Fischerindole Natural Products via Cascade Biocatalysis RM Hohlman, SA Newmister, JN Sanders, Y Khatri, S Li, NR Keramati, ... ACS Catalysis 11 (8), 4670-4681, 2021 | 6 | 2021 |
Synthesis and Cytotoxicity Evaluation of Naphthalimide Derived N-Mustards Q Lou, L Ji, W Zhong, S Li, S Yu, Z Li, X Meng Molecules 19 (7), 8803-8819, 2014 | 4 | 2014 |
Control of Stereoselectivity in Diverse Hapalindole Metabolites is Mediated by Cofactor‐Induced Combinatorial Pairing of Stig Cyclases S Li, SA Newmister, AN Lowell, J Zi, CR Chappell, F Yu, RM Hohlman, ... Angewandte Chemie International Edition 59 (21), 8166-8172, 2020 | 3 | 2020 |
Structural basis of the Cope rearrangement and C− C bond-forming cascade in hapalindole/fischerindole biogenesis SA Newmister, S Li, M Garcia-Borràs, JN Sanders, S Yang, AN Lowell, ... bioRxiv, 173674, 2017 | 2 | 2017 |
Accelerating Pharmaceutical Process Development with an Acoustic Droplet Ejection-Multiple Reaction Monitoring-Mass Spectrometry Workflow H Hu, AN Singh, D Lehnherr, V Mdluli, SW Chun, AM Makarewicz, ... Analytical Chemistry 96 (3), 1138-1146, 2024 | 1 | 2024 |
Function and structure of a new class of indole alkaloid cyclases in the Stigonematales cyanobacteria D Sherman, S Li, S Newmister, A Lowell, F Yu ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |
Biocatalyst discovery from the secondary metabolome DH Sherman, S Li, AN Lowell, SA Newmister, F Yu, RM Williams The FASEB Journal 31, 528.2-528.2, 2017 | | 2017 |
Decoding the Bio-Assembly of Hapalindole-Type Alkaloids from Cyanobacteria for Drug Discovery S Li | | 2017 |