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russell miller
Laronde
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Year
Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria
C Cárdenas, RA Miller, I Smith, T Bui, J Molgó, M Müller, H Vais, ...
Cell 142 (2), 270-283, 2010
9522010
Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin
WL Holland, RA Miller, ZV Wang, K Sun, BM Barth, HH Bui, KE Davis, ...
Nature medicine 17 (1), 55-63, 2011
9012011
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
RA Miller, Q Chu, J Xie, M Foretz, B Viollet, MJ Birnbaum
Nature 494 (7436), 256-260, 2013
8862013
MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca2+ uptake that regulates cell survival
K Mallilankaraman, P Doonan, C Cárdenas, HC Chandramoorthy, ...
Cell 151 (3), 630-644, 2012
5822012
MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
K Mallilankaraman, C Cárdenas, PJ Doonan, HC Chandramoorthy, ...
Nature cell biology 14 (12), 1336-1343, 2012
4942012
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
Z Sun, RA Miller, RT Patel, J Chen, R Dhir, H Wang, D Zhang, MJ Graham, ...
Nature medicine 18 (6), 934-942, 2012
2992012
An energetic tale of AMPK-independent effects of metformin
RA Miller, MJ Birnbaum
The Journal of clinical investigation 120 (7), 2267-2270, 2010
1982010
Activation of skeletal muscle AMPK promotes glucose disposal and glucose lowering in non-human primates and mice
EC Cokorinos, J Delmore, AR Reyes, B Albuquerque, R Kjøbsted, ...
Cell metabolism 25 (5), 1147-1159. e10, 2017
1962017
Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling
RA Miller, Q Chu, J Le Lay, PE Scherer, RS Ahima, KH Kaestner, M Foretz, ...
The Journal of clinical investigation 121 (6), 2518-2528, 2011
1872011
Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms
MF Calabrese, F Rajamohan, MS Harris, NL Caspers, R Magyar, ...
Structure 22 (8), 1161-1172, 2014
1602014
Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of …
KO Cameron, DW Kung, AS Kalgutkar, RG Kurumbail, R Miller, CT Salatto, ...
Journal of medicinal chemistry 59 (17), 8068-8081, 2016
1012016
Activation of liver AMPK with PF-06409577 corrects NAFLD and lowers cholesterol in rodent and primate preclinical models
RM Esquejo, CT Salatto, J Delmore, B Albuquerque, A Reyes, Y Shi, ...
EBioMedicine 31, 122-132, 2018
952018
Selective activation of AMPK β1-containing isoforms improves kidney function in a rat model of diabetic nephropathy
CT Salatto, RA Miller, KO Cameron, E Cokorinos, A Reyes, J Ward, ...
Journal of Pharmacology and Experimental Therapeutics 361 (2), 303-311, 2017
662017
Targeting hepatic glutaminase activity to ameliorate hyperglycemia
RA Miller, Y Shi, W Lu, DA Pirman, A Jatkar, M Blatnik, H Wu, C Cárdenas, ...
Nature medicine 24 (4), 518-524, 2018
462018
Glucagon: acute actions on hepatic metabolism
RA Miller, MJ Birnbaum
Diabetologia 59 (7), 1376-1381, 2016
402016
MCUR1 is an essential component of mitochondrial Ca (2+) uptake that regulates cellular metabolism
K Mallilankaraman, C Cárdenas, PJ Doonan, HC Chandramoorthy, ...
Nature cell biology 17 (7), 953, 2015
162015
The pleiotropic actions of adiponectin are initiated via receptor-mediated activation of ceramidase activity
WL Holland, RA Miller, ZV Wang, K Sun, BM Barth, HH Bui, KE Davis, ...
Nature medicine 17 (1), 55, 2011
162011
Ligand-regulated peptides: a general approach for modulating protein-peptide interactions with small molecules
BF Binkowski, RA Miller, PJ Belshaw
Chemistry & biology 12 (7), 847-855, 2005
152005
Ligand-regulated peptide aptamers that inhibit the 5′-AMP-activated protein kinase
RA Miller, BF Binkowski, PJ Belshaw
Journal of molecular biology 365 (4), 945-957, 2007
122007
Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid …
TF Ryder, MF Calabrese, GS Walker, KO Cameron, AR Reyes, ...
Journal of Medicinal Chemistry 61 (16), 7273-7288, 2018
112018
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