| Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria C Cárdenas, RA Miller, I Smith, T Bui, J Molgó, M Müller, H Vais, ... Cell 142 (2), 270-283, 2010 | 1094 | 2010 |
| Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP RA Miller, Q Chu, J Xie, M Foretz, B Viollet, MJ Birnbaum Nature 494 (7436), 256-260, 2013 | 1024 | 2013 |
| Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin WL Holland, RA Miller, ZV Wang, K Sun, BM Barth, HH Bui, KE Davis, ... Nature medicine 17 (1), 55-63, 2011 | 995 | 2011 |
| MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca2+ uptake that regulates cell survival K Mallilankaraman, P Doonan, C Cárdenas, HC Chandramoorthy, ... Cell 151 (3), 630-644, 2012 | 674 | 2012 |
| MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism K Mallilankaraman, C Cárdenas, PJ Doonan, HC Chandramoorthy, ... Nature cell biology 14 (12), 1336-1343, 2012 | 564 | 2012 |
| Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration Z Sun, RA Miller, RT Patel, J Chen, R Dhir, H Wang, D Zhang, MJ Graham, ... Nature medicine 18 (6), 934-942, 2012 | 335 | 2012 |
| Activation of skeletal muscle AMPK promotes glucose disposal and glucose lowering in non-human primates and mice EC Cokorinos, J Delmore, AR Reyes, B Albuquerque, R Kjøbsted, ... Cell metabolism 25 (5), 1147-1159. e10, 2017 | 244 | 2017 |
| An energetic tale of AMPK-independent effects of metformin RA Miller, MJ Birnbaum The Journal of clinical investigation 120 (7), 2267-2270, 2010 | 210 | 2010 |
| Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling RA Miller, Q Chu, J Le Lay, PE Scherer, RS Ahima, KH Kaestner, M Foretz, ... The Journal of clinical investigation 121 (6), 2518-2528, 2011 | 205 | 2011 |
| Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms MF Calabrese, F Rajamohan, MS Harris, NL Caspers, R Magyar, ... Structure 22 (8), 1161-1172, 2014 | 179 | 2014 |
| Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of … KO Cameron, DW Kung, AS Kalgutkar, RG Kurumbail, R Miller, CT Salatto, ... Journal of medicinal chemistry 59 (17), 8068-8081, 2016 | 120 | 2016 |
| Activation of liver AMPK with PF-06409577 corrects NAFLD and lowers cholesterol in rodent and primate preclinical models RM Esquejo, CT Salatto, J Delmore, B Albuquerque, A Reyes, Y Shi, ... EBioMedicine 31, 122-132, 2018 | 114 | 2018 |
| Selective activation of AMPK β1-containing isoforms improves kidney function in a rat model of diabetic nephropathy CT Salatto, RA Miller, KO Cameron, E Cokorinos, A Reyes, J Ward, ... Journal of Pharmacology and Experimental Therapeutics 361 (2), 303-311, 2017 | 78 | 2017 |
| Targeting hepatic glutaminase activity to ameliorate hyperglycemia RA Miller, Y Shi, W Lu, DA Pirman, A Jatkar, M Blatnik, H Wu, C Cárdenas, ... Nature medicine 24 (4), 518-524, 2018 | 61 | 2018 |
| Glucagon: acute actions on hepatic metabolism RA Miller, MJ Birnbaum Diabetologia 59, 1376-1381, 2016 | 59 | 2016 |
| Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid … TF Ryder, MF Calabrese, GS Walker, KO Cameron, AR Reyes, ... Journal of medicinal chemistry 61 (16), 7273-7288, 2018 | 21 | 2018 |
| MCUR1 is an essential component of mitochondrial Ca (2+) uptake that regulates cellular metabolism K Mallilankaraman, C Cárdenas, PJ Doonan, HC Chandramoorthy, ... Nature cell biology 17 (7), 953, 2015 | 20 | 2015 |
| The pleiotropic actions of adiponectin are initiated via receptor-mediated activation of ceramidase activity WL Holland, RA Miller, ZV Wang, K Sun, BM Barth, HH Bui, KE Davis, ... Nature medicine 17 (1), 55, 2011 | 18 | 2011 |
| BDK inhibition acts as a catabolic switch to mimic fasting and improve metabolism in mice E Bollinger, M Peloquin, J Libera, B Albuquerque, E Pashos, A Shipstone, ... Molecular Metabolism 66, 101611, 2022 | 17 | 2022 |
| Erratum: MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism K Mallilankaraman, C Cárdenas, PJ Doonan, HC Chandramoorthy, ... Nature Cell Biology 15 (1), 123-123, 2013 | 15 | 2013 |
