| Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B DAE Cross, DR Alessi, P Cohen, M Andjelkovich, BA Hemmings Nature 378 (6559), 785-789, 1995 | 6616 | 1995 |
| Specificity and mechanism of action of some commonly used protein kinase inhibitors SP Davies, H Reddy, M Caivano, P Cohen Biochemical Journal 351 (1), 95-105, 2000 | 5420 | 2000 |
| PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo DR Alessi, A Cuenda, P Cohen, DT Dudley, AR Saltiel Journal of Biological Chemistry 270 (46), 27489-27494, 1995 | 4130 | 1995 |
| Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα DR Alessi, SR James, CP Downes, AB Holmes, PRJ Gaffney, CB Reese, ... Current biology 7 (4), 261-269, 1997 | 3919 | 1997 |
| Mechanism of activation of protein kinase B by insulin and IGF‐1. DR Alessi, M Andjelkovic, B Caudwell, P Cron, N Morrice, P Cohen, ... The EMBO journal 15 (23), 6541-6551, 1996 | 3891 | 1996 |
| The ground state of embryonic stem cell self-renewal QL Ying, J Wray, J Nichols, L Batlle-Morera, B Doble, J Woodgett, ... nature 453 (7194), 519-523, 2008 | 3882 | 2008 |
| The structure and regulation of protein phosphatases P Cohen Annual review of biochemistry 58 (1), 453-508, 1989 | 3304 | 1989 |
| The selectivity of protein kinase inhibitors: a further update J Bain, L Plater, M Elliott, N Shpiro, CJ Hastie, H Mclauchlan, I Klevernic, ... Biochemical Journal 408 (3), 297-315, 2007 | 3016 | 2007 |
| Protein kinases—the major drug targets of the twenty-first century? P Cohen Nature reviews Drug discovery 1 (4), 309-315, 2002 | 2946 | 2002 |
| SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1 A Cuenda, J Rouse, YN Doza, R Meier, P Cohen, TF Gallagher, ... FEBS letters 364 (2), 229-233, 1995 | 2478 | 1995 |
| A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins J Rouse, P Cohen, S Trigon, M Morange, A Alonso-Llamazares, ... Cell 78 (6), 1027-1037, 1994 | 2162 | 1994 |
| Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants C MacKintosh, KA Beattie, S Klumpp, P Cohen, GA Codd FEBS letters 264 (2), 187-192, 1990 | 2033 | 1990 |
| The renaissance of GSK3 P Cohen, S Frame Nature reviews Molecular cell biology 2 (10), 769-776, 2001 | 1937 | 2001 |
| GSK3 takes centre stage more than 20 years after its discovery S Frame, P Cohen Biochemical Journal 359 (1), 1-16, 2001 | 1929 | 2001 |
| The specificities of protein kinase inhibitors: an update J Bain, H McLauchlan, M Elliott, P Cohen Biochemical Journal 371 (1), 199-204, 2003 | 1769 | 2003 |
| Okadaic acid: a new probe for the study of cellular regulation P Cohen, CFB Holmes, Y Tsukitani Trends in biochemical sciences 15 (3), 98-102, 1990 | 1734 | 1990 |
| The regulation of protein function by multisite phosphorylation–a 25 year update P Cohen Trends in biochemical sciences 25 (12), 596-601, 2000 | 1476 | 2000 |
| The origins of protein phosphorylation P Cohen Nature cell biology 4 (5), E127-E130, 2002 | 1447 | 2002 |
| Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1 JA Le Good, WH Ziegler, DB Parekh, DR Alessi, P Cohen, PJ Parker Science 281 (5385), 2042-2045, 1998 | 1433 | 1998 |
| The role of protein phosphorylation in neural and hormonal control of cellular activity P Cohen Nature 296 (5858), 613-620, 1982 | 1404 | 1982 |
