Geir Slupphaug
Geir Slupphaug
Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, NTNU
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Sitert av
Sitert av
DNA glycosylases in the base excision repair of DNA
Biochemical Journal 325 (1), 1-16, 1997
Alkylation damage in DNA and RNA—repair mechanisms and medical significance
F Drabløs, E Feyzi, PA Aas, CB Vaagbø, B Kavli, MS Bratlie, J Peña-Diaz, ...
DNA repair 3 (11), 1389-1407, 2004
The interacting pathways for prevention and repair of oxidative DNA damage
G Slupphaug, B Kavli, HE Krokan
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 531 (1 …, 2003
Human uracil–DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination
K Imai, G Slupphaug, WI Lee, P Revy, S Nonoyama, N Catalan, L Yel, ...
Nature immunology 4 (10), 1023-1028, 2003
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA
PA Aas, M Otterlei, PØ Falnes, CB Vågbø, F Skorpen, M Akbari, ...
Nature 421 (6925), 859-863, 2003
A nucleotide-flipping mechanism from the structure of human uracil–DNA glycosylase bound to DNA
G Slupphaug, CD Mol, B Kavli, AS Arvai, HE Krokan, JA Tainer
Nature 384 (6604), 87-92, 1996
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil‐DNA glycosylase with DNA
SS Parikh, CD Mol, G Slupphaug, S Bharati, HE Krokan, JA Tainer
The EMBO journal 17 (17), 5214-5226, 1998
Uracil in DNA–occurrence, consequences and repair
HE Krokan, F Drabløs, G Slupphaug
Oncogene 21 (58), 8935-8948, 2002
Base excision repair of DNA in mammalian cells
HE Krokan, H Nilsen, F Skorpen, M Otterlei, G Slupphaug
FEBS letters 476 (1-2), 73-77, 2000
Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis
CD Mol, AS Arvai, G Slupphaug, B Kavli, I Alseth, HE Krokan, JA Tainer
Cell 80 (6), 869-878, 1995
Post‐replicative base excision repair in replication foci
M Otterlei, E Warbrick, TA Nagelhus, T Haug, G Slupphaug, M Akbari, ...
The EMBO journal 18 (13), 3834-3844, 1999
Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication
H Nilsen, I Rosewell, P Robins, CF Skjelbred, S Andersen, G Slupphaug, ...
Molecular cell 5 (6), 1059-1065, 2000
hUNG2 is the major repair enzyme for removal of uracil from U: A matches, U: G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup
B Kavli, O Sundheim, M Akbari, M Otterlei, H Nilsen, F Skorpen, PA Aas, ...
Journal of Biological Chemistry 277 (42), 39926-39936, 2002
Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA
CD Mol, AS Arvai, RJ Sanderson, G Slupphaug, B Kavli, HE Krokan, ...
Cell 82 (5), 701-708, 1995
Properties of a recombinant human uracil-DNA glycosylase from the UNG gene and evidence that UNG encodes the major uracil-DNA glycosylase
G Slupphaug, I Eftedal, B Kavli, S Bharati, NM Helle, T Haug, DW Levine, ...
Biochemistry 34 (1), 128-138, 1995
Uracil-DNA glycosylase–DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects
SS Parikh, G Walcher, GD Jones, G Slupphaug, HE Krokan, ...
Proceedings of the National Academy of Sciences 97 (10), 5083-5088, 2000
Glucocorticoids inhibit the production of IL 6 from monocytes, endothelial cells and fibroblasts
A Waage, G Slupphaug, R Shalaby
European journal of immunology 20 (11), 2439-2443, 1990
Synergistic actions of Ogg1 and mutyh DNA glycosylases modulate anxiety-like behavior in mice
MD Bjørge, GA Hildrestrand, K Scheffler, R Suganthan, V Rolseth, ...
Cell reports 13 (12), 2671-2678, 2015
Human immunodeficiency virus type 1 Vpr protein binds to the uracil DNA glycosylase DNA repair enzyme
M BouHamdan, S Benichou, F Rey, JM Navarro, I Agostini, B Spire, ...
Journal of virology 70 (2), 697-704, 1996
Excision of cytosine and thymine from DNA by mutants of human uracil‐DNA glycosylase.
B Kavli, G Slupphaug, CD Mol, AS Arvai, SB Peterson, JA Tainer, ...
The EMBO journal 15 (13), 3442-3447, 1996
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