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Chaolin Zhang
Chaolin Zhang
Associate Professor @ Columbia University Medical Center
Verified email at columbia.edu - Homepage
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Year
An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex
Y Zhang, K Chen, SA Sloan, ML Bennett, AR Scholze, S O'Keeffe, ...
Journal of Neuroscience 34 (36), 11929-11947, 2014
37952014
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism
JC Darnell, SJ Van Driesche, C Zhang, KYS Hung, A Mele, CE Fraser, ...
Cell 146 (2), 247-261, 2011
19082011
An increased specificity score matrix for the prediction of SF2/ASF-specific exonic splicing enhancers
PJ Smith, C Zhang, J Wang, SL Chew, MQ Zhang, AR Krainer
Human molecular genetics 15 (16), 2490-2508, 2006
5712006
The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult
B Zhang, G Arun, YS Mao, Z Lazar, G Hung, G Bhattacharjee, X Xiao, ...
Cell reports 2 (1), 111-123, 2012
5372012
Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data
C Zhang, RB Darnell
Nature biotechnology 29 (7), 607-614, 2011
4282011
Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence
A Chicas, X Wang, C Zhang, M McCurrach, Z Zhao, O Mert, RA Dickins, ...
Cancer cell 17 (4), 376-387, 2010
3662010
Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines
JC Castle, C Zhang, JK Shah, AV Kulkarni, A Kalsotra, TA Cooper, ...
Nature genetics 40 (12), 1416-1425, 2008
3442008
HITS-CLIP and Integrative Modeling Define the Rbfox Splicing-Regulatory Network Linked to Brain Development and Autism
SM Weyn-Vanhentenryck, A Mele, Q Yan, S Sun, N Farny, Z Zhang, ...
Cell reports 6 (6), 1139-1152, 2014
3262014
Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2
C Zhang, Z Zhang, J Castle, S Sun, J Johnson, AR Krainer, MQ Zhang
Genes & development 22 (18), 2550-2563, 2008
3192008
Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy
K Charizanis, KY Lee, R Batra, M Goodwin, C Zhang, Y Yuan, L Shiue, ...
Neuron 75 (3), 437-450, 2012
3162012
Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls
C Zhang, MA Frias, A Mele, M Ruggiu, T Eom, CB Marney, H Wang, ...
Science 329 (5990), 439-443, 2010
3012010
Loss of MBNL leads to disruption of developmentally regulated alternative polyadenylation in RNA-mediated disease
R Batra, K Charizanis, M Manchanda, A Mohan, M Li, DJ Finn, ...
Molecular cell 56 (2), 311-322, 2014
2702014
Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis
MJ Moore, C Zhang, EC Gantman, A Mele, JC Darnell, RB Darnell
Nature protocols 9 (2), 263-293, 2014
2422014
Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability
G Ince-Dunn, HJ Okano, KB Jensen, WY Park, R Zhong, J Ule, A Mele, ...
Neuron 75 (6), 1067-1080, 2012
1892012
Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain
DD Licatalosi, M Yano, JJ Fak, A Mele, SE Grabinski, C Zhang, ...
Genes & development 26 (14), 1626-1642, 2012
1862012
OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds
J Wu, O Anczuków, AR Krainer, MQ Zhang, C Zhang
Nucleic acids research 41 (10), 5149-5163, 2013
1322013
RNA landscape of evolution for optimal exon and intron discrimination
C Zhang, WH Li, AR Krainer, MQ Zhang
Proceedings of the National Academy of Sciences 105 (15), 5797-5802, 2008
1322008
Precise temporal regulation of alternative splicing during neural development
SM Weyn-Vanhentenryck, H Feng, D Ustianenko, R Duffie, Q Yan, ...
Nature Communications, 2189, 2018
1272018
Capturing the interactome of newly transcribed RNA
X Bao, X Guo, M Yin, M Tariq, Y Lai, S Kanwal, J Zhou, N Li, Y Lv, ...
Nature methods 15 (3), 213, 2018
1262018
Systematic discovery of regulated and conserved alternative exons in the mammalian brain reveals NMD modulating chromatin regulators
Q Yan, SM Weyn-Vanhentenryck, J Wu, SA Sloan, Y Zhang, K Chen, ...
Proceedings of the National Academy of Sciences 112 (11), 3445-3450, 2015
1252015
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