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Clair Crewe
Clair Crewe
Verified email at wustl.edu
Title
Cited by
Cited by
Year
The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis
C Crewe, YA An, PE Scherer
The Journal of clinical investigation 127 (1), 74-82, 2017
6342017
An endothelial-to-adipocyte extracellular vesicle axis governed by metabolic state
C Crewe, N Joffin, JM Rutkowski, M Kim, F Zhang, DA Towler, R Gordillo, ...
Cell 175 (3), 695-708. e13, 2018
3162018
Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes
C Crewe, JB Funcke, S Li, N Joffin, CM Gliniak, AL Ghaben, YA An, ...
Cell metabolism 33 (9), 1853-1868. e11, 2021
2092021
Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice
Z Zhang, M Shao, C Hepler, Z Zi, S Zhao, YA An, Y Zhu, AL Ghaben, ...
The Journal of clinical investigation 129 (12), 5327-5342, 2019
1422019
Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria
PM Rindler, CL Crewe, J Fernandes, M Kinter, LI Szweda
American Journal of Physiology-Heart and Circulatory Physiology 305 (5 …, 2013
642013
Rapid inhibition of pyruvate dehydrogenase: an initiating event in high dietary fat-induced loss of metabolic flexibility in the heart
C Crewe, M Kinter, LI Szweda
PloS one 8 (10), e77280, 2013
612013
Human endotrophin as a driver of malignant tumor growth
D Bu, C Crewe, CM Kusminski, R Gordillo, AL Ghaben, M Kim, J Park, ...
JCI insight 4 (9), 2019
592019
Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity
Z Zhang, JB Funcke, Z Zi, S Zhao, LG Straub, Y Zhu, Q Zhu, C Crewe, ...
Cell metabolism 33 (8), 1624-1639. e9, 2021
572021
Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood
N Borcherding, W Jia, R Giwa, RL Field, JR Moley, BJ Kopecky, MM Chan, ...
Cell metabolism 34 (10), 1499-1513. e8, 2022
542022
SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1
C Crewe, Y Zhu, VA Paschoal, N Joffin, AL Ghaben, R Gordillo, G Liang, ...
JCI insight 4 (15), 2019
502019
Regulation of pyruvate dehydrogenase kinase 4 in the heart through degradation by the Lon protease in response to mitochondrial substrate availability
C Crewe, C Schafer, I Lee, M Kinter, LI Szweda
Journal of Biological Chemistry 292 (1), 305-312, 2017
492017
A novel model of diabetic complications: adipocyte mitochondrial dysfunction triggers massive β-cell hyperplasia
CM Kusminski, AL Ghaben, TS Morley, RJ Samms, AC Adams, Y An, ...
Diabetes 69 (3), 313-330, 2020
452020
Dysregulation of amyloid precursor protein impairs adipose tissue mitochondrial function and promotes obesity
YA An, C Crewe, IW Asterholm, K Sun, S Chen, F Zhang, M Shao, ...
Nature metabolism 1 (12), 1243-1257, 2019
442019
Mitochondrial metabolism is a key regulator of the fibro-inflammatory and adipogenic stromal subpopulations in white adipose tissue
N Joffin, VA Paschoal, CM Gliniak, C Crewe, A Elnwasany, LI Szweda, ...
Cell Stem Cell 28 (4), 702-717. e8, 2021
412021
Hyaluronan in adipose tissue: Beyond dermal filler and therapeutic carrier
Y Zhu, C Crewe, PE Scherer
Science translational medicine 8 (323), 323ps4-323ps4, 2016
412016
Intercellular and interorgan crosstalk through adipocyte extracellular vesicles
C Crewe, PE Scherer
Reviews in Endocrine and Metabolic Disorders 23 (1), 61-69, 2022
362022
Adipocyte mesenchymal transition contributes to mammary tumor progression
Q Zhu, Y Zhu, C Hepler, Q Zhang, J Park, C Gliniak, GH Henry, C Crewe, ...
Cell reports 40 (11), 2022
322022
Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis
Y Zhu, N Li, M Huang, M Bartels, S Dogné, S Zhao, X Chen, C Crewe, ...
Nature communications 12 (1), 4829, 2021
222021
Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus
R Yang, EE Lee, J Kim, JH Choi, E Kolitz, Y Chen, C Crewe, ...
PLoS pathogens 17 (5), e1009582, 2021
222021
Adipose tissue macrophages exert systemic metabolic control by manipulating local iron concentrations
N Joffin, CM Gliniak, JB Funcke, VA Paschoal, C Crewe, S Chen, ...
Nature Metabolism 4 (11), 1474-1494, 2022
202022
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