| Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa T Sengoku, O Nureki, A Nakamura, S Kobayashi, S Yokoyama Cell 125 (2), 287-300, 2006 | 646 | 2006 |
| UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development KB Shpargel, T Sengoku, S Yokoyama, T Magnuson Public Library of Science 8 (9), e1002964, 2012 | 311 | 2012 |
| SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53 Z Tang, WY Chen, M Shimada, UTT Nguyen, J Kim, XJ Sun, T Sengoku, ... Cell 154 (2), 297-310, 2013 | 170 | 2013 |
| A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase Y Kise, SW Lee, SG Park, S Fukai, T Sengoku, R Ishii, S Yokoyama, S Kim, ... Nature structural & molecular biology 11 (2), 149-156, 2004 | 169 | 2004 |
| Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A T Sengoku, S Yokoyama Genes & development 25 (21), 2266-2277, 2011 | 160 | 2011 |
| Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 Å S Mimasu, T Sengoku, S Fukuzawa, T Umehara, S Yokoyama Biochemical and biophysical research communications 366 (1), 15-22, 2008 | 155 | 2008 |
| Ribosomal synthesis and de novo discovery of bioactive foldamer peptides containing cyclic β-amino acids T Katoh, T Sengoku, K Hirata, K Ogata, H Suga Nature Chemistry 12 (11), 1081-1088, 2020 | 90 | 2020 |
| Crystal structure of tRNA adenosine deaminase (TadA) from Aquifex aeolicus M Kuratani, R Ishii, Y Bessho, R Fukunaga, T Sengoku, M Shirouzu, ... Journal of Biological Chemistry 280 (16), 16002-16008, 2005 | 73 | 2005 |
| Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase HM Sasaki, S Sekine, T Sengoku, R Fukunaga, M Hattori, Y Utsunomiya, ... Proceedings of the National Academy of Sciences 103 (40), 14744-14749, 2006 | 49 | 2006 |
| Genetic landscape of Rett syndrome-like phenotypes revealed by whole exome sequencing K Iwama, T Mizuguchi, E Takeshita, E Nakagawa, T Okazaki, Y Nomura, ... Journal of medical genetics 56 (6), 396-407, 2019 | 37 | 2019 |
| An ultrapotent and selective cyclic peptide inhibitor of human β-factor XIIa in a cyclotide scaffold W Liu, SJ de Veer, YH Huang, T Sengoku, C Okada, K Ogata, CN Zdenek, ... Journal of the American Chemical Society 143 (44), 18481-18489, 2021 | 27 | 2021 |
| Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP T Sengoku, T Suzuki, N Dohmae, C Watanabe, T Honma, Y Hikida, ... Nature Chemical Biology 14 (4), 368-374, 2018 | 26 | 2018 |
| De Novo discovery of thiopeptide pseudo-natural products acting as potent and selective TNIK kinase inhibitors AA Vinogradov, Y Zhang, K Hamada, JS Chang, C Okada, H Nishimura, ... Journal of the American Chemical Society 144 (44), 20332-20341, 2022 | 24 | 2022 |
| Substrate tRNA recognition mechanism of a multisite-specific tRNA methyltransferase, Aquifex aeolicus Trm1, based on the X-ray crystal structure T Awai, A Ochi, T Sengoku, A Hirata, Y Bessho, S Yokoyama, H Hori Journal of Biological Chemistry 286 (40), 35236-35246, 2011 | 24 | 2011 |
| Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2 K Sato, A Kumar, K Hamada, C Okada, A Oguni, A Machiyama, ... Nature Communications 12 (1), 6605, 2021 | 23 | 2021 |
| Phenotype–genotype correlations in patients with GNB1 gene variants, including the first three reported Japanese patients to exhibit spastic diplegia, dyskinetic quadriplegia … W Endo, S Ikemoto, N Togashi, T Miyabayashi, E Nakajima, S Hamano, ... Brain and Development 42 (2), 199-204, 2020 | 23 | 2020 |
| Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder M Nishioka, A Kazuno, T Nakamura, N Sakai, T Hayama, K Fujii, ... Nature communications 12 (1), 3750, 2021 | 20 | 2021 |
| Development and Structural Evaluation of N‐Alkylated trans‐2‐Phenylcyclopropylamine‐Based LSD1 Inhibitors H Niwa, S Sato, N Handa, T Sengoku, T Umehara, S Yokoyama ChemMedChem 15 (9), 787-793, 2020 | 20 | 2020 |
| Thioether macrocyclic peptides selected against TET1 compact catalytic domain inhibit TET1 catalytic activity K Nishio, R Belle, T Katoh, A Kawamura, T Sengoku, K Hanada, ... ChemBioChem 19 (9), 979-985, 2018 | 18 | 2018 |
| Structural basis of transcription regulation by CNC family transcription factor, Nrf2 T Sengoku, M Shiina, K Suzuki, K Hamada, K Sato, A Uchiyama, ... Nucleic Acids Research 50 (21), 12543-12557, 2022 | 17 | 2022 |
Yasushi HIKIDA理化学研究所Verified email at alum.riken.jp
