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Lorna Cryan
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Targeting the anthrax receptors, TEM-8 and CMG-2, for anti-angiogenic therapy
LM Cryan, MS Rogers
Frontiers in bioscience: a journal and virtual library 16, 1574, 2011
672011
Microvascular retinal endothelial and pericyte cell apoptosis in vitro: role of hedgehog and Notch signaling
TE Walshe, P Connell, L Cryan, G Ferguson, T Gardiner, D Morrow, ...
Investigative ophthalmology & visual science 52 (7), 4472-4483, 2011
522011
Conjugated linoleic acid suppresses the migratory and inflammatory phenotype of the monocyte/macrophage cell
S McClelland, C Cox, R O’Connor, M de Gaetano, C McCarthy, L Cryan, ...
Atherosclerosis 211 (1), 96-102, 2010
482010
A FRET-based high throughput screening assay to identify inhibitors of anthrax protective antigen binding to capillary morphogenesis gene 2 protein
MS Rogers, LM Cryan, KA Habeshian, L Bazinet, TP Caldwell, ...
PloS one 7 (6), e39911, 2012
452012
1,2,3,4,6-Penta-O-galloyl-β-d-glucopyranose Inhibits Angiogenesis via Inhibition of Capillary Morphogenesis Gene 2
LM Cryan, L Bazinet, KA Habeshian, S Cao, J Clardy, KA Christensen, ...
Journal of medicinal chemistry 56 (5), 1940-1945, 2013
372013
Phenolic compounds as antiangiogenic CMG2 inhibitors from Costa Rican endophytic fungi
S Cao, L Cryan, KA Habeshian, C Murillo, G Tamayo-Castillo, MS Rogers, ...
Bioorganic & medicinal chemistry letters 22 (18), 5885-5888, 2012
302012
Identification of small molecules that inhibit the interaction of TEM8 with anthrax protective antigen using a FRET assay
LM Cryan, KA Habeshian, TP Caldwell, MT Morris, PC Ackroyd, ...
Journal of biomolecular screening 18 (6), 714-725, 2013
262013
Expression of COX-2 and prognostic outcome in uveal melanoma
LM Cryan, L Paraoan, P Hiscott, BE Damato, I Grierson, D Gray, M Farrell, ...
Current eye research 33 (2), 177-184, 2008
252008
Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors
MS Rogers, K Novak, D Zurakowski, LM Cryan, A Blois, E Lifshits, TH Bø, ...
Molecular Cancer Research 12 (5), 754-764, 2014
242014
The role of pulsatile flow in controlling microvascular retinal endothelial and pericyte cell apoptosis and proliferation
TE Walshe, P Connell, L Cryan, G Ferguson, C O'Brien, PA Cahill
Cardiovascular research 89 (3), 661-670, 2011
192011
Proteomics as a research tool in clinical and experimental ophthalmology
LM Cryan, C O'Brien
PROTEOMICS–Clinical Applications 2 (5), 762-775, 2008
182008
COX-2 protects against thrombosis of the retinal vasculature in a mouse model of proliferative retinopathy.
LM Cryan, GP Pidgeon, DJ Fitzgerald, CJ O'Brien
Mol Vis 12, 405-14, 2006
152006
Proteomics strategy for identifying candidate bioactive proteins in complex mixtures: application to the platelet releasate
R O'Connor, LM Cryan, K Wynne, A de Stefani, D Fitzgerald, C O'Brien, ...
BioMed Research International 2010, 2010
142010
Capillary morphogenesis gene 2 (CMG2) mediates growth factor-induced angiogenesis by regulating endothelial cell chemotaxis
LM Cryan, TM Tsang, J Stiles, L Bazinet, SL Lee, S Garrard, E Madrian, ...
Angiogenesis 25 (3), 397-410, 2022
72022
Ocular prostaglandin production and morphology in mice lacking a single isoform of cyclooxygenase
LM Cryan, DJ Fitzgerald, C O’Brien
Prostaglandins, Leukotrienes and Essential Fatty Acids 81 (5-6), 401-409, 2009
62009
A canstatin-derived peptide provides insight into the role of capillary morphogenesis gene 2 in angiogenic regulation and matrix uptake
JG Finnell, TM Tsang, L Cryan, S Garrard, SL Lee, PC Ackroyd, ...
ACS Chemical Biology 15 (2), 587-596, 2020
52020
Integrative Proteomics: Structure, function, and interaction Report on the 3rd joint meeting of the British Society for Proteome Research and the European …
LM Cryan, N O'Donoghue
Proteomics 6 (22), 5894-5897, 2006
42006
Antiangiogenic small molecule antagonists of the anthrax toxin receptor CMG2.
LM Cryan, PC Ackroyd, S Cao, J Clardy, KA Christensen, MS Rogers
Cancer Research 73 (8_Supplement), 3890-3890, 2013
22013
Capillary Morphogenesis gene 2 mediates multiple pathways of growth factor-induced angiogenesis by regulating endothelial cell chemotaxis
L Cryan, TM Tsang, J Stiles, L Bazinet, SL Lee, S Garrard, C Roberts, ...
bioRxiv, 705442, 2019
2019
Identification and anti-angiogenic effects of small molecule inhibitors of TEM8.
L Cryan, M Roznik, A McBride, R D'Amato, K Christensen, MS Rogers
Cancer Research 73 (8_Supplement), 5076-5076, 2013
2013
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