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Philip L. De Jager
Philip L. De Jager
Weil-Granat Professor of Neurology at Columbia University
Verifisert e-postadresse på cumc.columbia.edu
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Integrative analysis of 111 reference human epigenomes
A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ...
Nature 518 (7539), 317-330, 2015
61292015
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ...
Nature genetics 45 (12), 1452-1458, 2013
44242013
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Nature 476 (7359), 214-219, 2011
30102011
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
JZ Liu, S Van Sommeren, H Huang, SC Ng, R Alberts, A Takahashi, ...
Nature genetics 47 (9), 979-986, 2015
25142015
Genetics of rheumatoid arthritis contributes to biology and drug discovery
Y Okada, D Wu, G Trynka, T Raj, C Terao, K Ikari, Y Kochi, K Ohmura, ...
Nature 506 (7488), 376-381, 2014
25072014
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
22922019
Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors
AC Villani, R Satija, G Reynolds, S Sarkizova, K Shekhar, J Fletcher, ...
Science 356 (6335), eaah4573, 2017
22292017
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ...
Nature genetics 43 (5), 436-441, 2011
21692011
Risk alleles for multiple sclerosis identified by a genomewide study
International Multiple Sclerosis Genetics Consortium
New England Journal of Medicine 357 (9), 851-862, 2007
21032007
Genetic and epigenetic fine mapping of causal autoimmune disease variants
KKH Farh, A Marson, J Zhu, M Kleinewietfeld, WJ Housley, S Beik, ...
Nature 518 (7539), 337-343, 2015
19772015
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
EA Stahl, S Raychaudhuri, EF Remmers, G Xie, S Eyre, BP Thomson, Y Li, ...
Nature genetics 42 (6), 508-514, 2010
15822010
Charting a dynamic DNA methylation landscape of the human genome
MJ Ziller, H Gu, F Müller, J Donaghey, LTY Tsai, O Kohlbacher, ...
Nature 500 (7463), 477-481, 2013
14312013
Genome-wide association study identifies 74 loci associated with educational attainment
A Okbay, JP Beauchamp, MA Fontana, JJ Lee, TH Pers, CA Rietveld, ...
Nature 533 (7604), 539-542, 2016
14112016
Analysis of shared heritability in common disorders of the brain
Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ...
Science 360 (6395), eaap8757, 2018
13772018
Modeling linkage disequilibrium increases accuracy of polygenic risk scores
BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ...
The american journal of human genetics 97 (4), 576-592, 2015
13582015
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
International IBD Genetics Consortium (IIBDGC), C Agliardi, L Alfredsson, ...
Nature genetics 45 (11), 1353-1360, 2013
13482013
Alterations of the human gut microbiome in multiple sclerosis
S Jangi, R Gandhi, LM Cox, N Li, F Von Glehn, R Yan, B Patel, ...
Nature communications 7 (1), 12015, 2016
11952016
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
A Okbay, BML Baselmans, JE De Neve, P Turley, MG Nivard, MA Fontana, ...
Nature genetics 48 (6), 624-633, 2016
10972016
Gene expression elucidates functional impact of polygenic risk for schizophrenia
M Fromer, P Roussos, SK Sieberts, JS Johnson, DH Kavanagh, ...
Nature neuroscience 19 (11), 1442-1453, 2016
10872016
Parkinson's disease: genetics and pathogenesis
JM Shulman, PL De Jager, MB Feany
Annual Review of Pathology: Mechanisms of Disease 6 (1), 193-222, 2011
10242011
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Artikler 1–20