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Nils Eling
Nils Eling
Senior data scientist at NIBR, Novartis
Ingen verifisert e-postadresse - Startside
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Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells
N Eling, L Reuter, J Hazin, A Hamacher-Brady, NR Brady
Oncoscience 2 (5), 517, 2015
4852015
Aging increases cell-to-cell transcriptional variability upon immune stimulation
CP Martinez-Jimenez, N Eling, HC Chen, CA Vallejos, AA Kolodziejczyk, ...
Science 355 (6332), 1433-1436, 2017
3102017
Staged developmental mapping and X chromosome transcriptional dynamics during mouse spermatogenesis
C Ernst, N Eling, CP Martinez-Jimenez, JC Marioni, DT Odom
Nature communications 10 (1), 1251, 2019
1972019
Challenges in measuring and understanding biological noise
N Eling, MD Morgan, JC Marioni
Nature Reviews Genetics 20 (9), 536-548, 2019
1762019
Multiplexed imaging mass cytometry of the chemokine milieus in melanoma characterizes features of the response to immunotherapy
T Hoch, D Schulz, N Eling, JM Gómez, MP Levesque, B Bodenmiller
Science immunology 7 (70), eabk1692, 2022
1142022
Molecular phenotyping reveals the identity of Barrett’s esophagus and its malignant transition
K Nowicki-Osuch, L Zhuang, S Jammula, CW Bleaney, KT Mahbubani, ...
Science 373 (6556), 760-767, 2021
1132021
Correcting the mean-variance dependency for differential variability testing using single-cell RNA sequencing data
N Eling, AC Richard, S Richardson, JC Marioni, CA Vallejos
Cell systems 7 (3), 284-294. e12, 2018
752018
Whole-body single-cell sequencing reveals transcriptional domains in the annelid larval body
K Achim, N Eling, HM Vergara, PY Bertucci, J Musser, P Vopalensky, ...
Molecular biology and evolution 35 (5), 1047-1062, 2018
562018
An end-to-end workflow for multiplexed image processing and analysis
J Windhager, VRT Zanotelli, D Schulz, L Meyer, M Daniel, B Bodenmiller, ...
Nature Protocols, 1-49, 2023
522023
IL‐7‐dependent compositional changes within the γδ T cell pool in lymph nodes during ageing lead to an unbalanced anti‐tumour response
HC Chen, N Eling, CP Martinez‐Jimenez, LMN O'Brien, V Carbonaro, ...
EMBO reports 20 (8), e47379, 2019
472019
cytomapper: an R/Bioconductor package for visualization of highly multiplexed imaging data
N Eling, N Damond, T Hoch, B Bodenmiller
Bioinformatics 36 (24), 5706–5708, 2020
432020
Sirtuin 1 stimulates the proliferation and the expression of glycolysis genes in pancreatic neoplastic lesions
AV Pinho, A Mawson, A Gill, M Arshi, M Warmerdam, M Giry-Laterriere, ...
Oncotarget 7 (46), 74768, 2016
292016
Emerging Drug Target In Pancreatic Cancer: Placing Sirtuin 1 on the Canvas
M Giry-Laterriere, AV Pinho, N Eling, L Chantrill, I Rooman
Current Cancer Drug Targets 15, 2015
62015
Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis
C Ernst, J Pike, SJ Aitken, HK Long, N Eling, L Stojic, MC Ward, F Connor, ...
ELife 5, e20235, 2016
32016
A toolbox enabling a data-driven selection of regions of interest in tumor tissue sections for imaging mass cytometry analysis
D Schulz, S Renaud-Tissot, R Liechti, N Eling, M Daniel, J Windhager, ...
Cancer Research 81 (13_Supplement), 2756-2756, 2021
12021
Microenvironmental reorganization in brain tumors following radiotherapy and recurrence revealed by hyperplexed immunofluorescence imaging
SS Watson, B Duc, Z Kang, A de Tonnac, N Eling, L Font, T Whitmarsh, ...
Nature Communications 15 (1), 3226, 2024
2024
The dynamic genetic determinants of increased transcriptional divergence in spermatids
J Panten, T Heinen, C Ernst, N Eling, RE Wagner, M Satorius, JC Marioni, ...
Nature Communications 15 (1), 1272, 2024
2024
cytoviewer: an R/Bioconductor package for interactive visualization and exploration of highly multiplexed imaging data
L Meyer, N Eling, B Bodenmiller
BMC bioinformatics 25 (1), 9, 2024
2024
199P Scalable multiplexed image analysis across cancer types as part of the IMMUcan consortium
N Eling, J Dorier, S Rusakiewicz, S Tissot, P Devanand, M Daniel, ...
Immuno-Oncology and Technology 20, 2023
2023
202P Discovery of immunological cellular neighborhoods from protein markers in spatial tumor data
M Możejko, K Gogolewski, D Schulz, N Eling, J Krawczyk, A Możwiłło, ...
Immuno-Oncology and Technology 20, 2023
2023
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Artikler 1–20