Erik Sontheimer

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Aamir MirDirector at CRISPR TherapeuticsVerifisert e-postadresse på crisprtx.com
Luciano MarraffiniThe Rockefeller UniversityVerifisert e-postadresse på rockefeller.edu
Wen Xuethe RNA Therapeutics Institute at the University of Massachusetts Medical SchoolVerifisert e-postadresse på umassmed.edu
Alan R. DavidsonUniversity of TorontoVerifisert e-postadresse på utoronto.ca
Karen MaxwellProfessor, University of TorontoVerifisert e-postadresse på utoronto.ca
GuangPing GaoVerifisert e-postadresse på umassmed.edu
Jonathan K. WattsProfessor, RNA Therapeutics Institute, UMass Chan Medical SchoolVerifisert e-postadresse på umassmed.edu
Lihua Julie ZhuProfessor and Head of Bioinformatics Core, MCCB, University of Massachusetts Medical SchoolVerifisert e-postadresse på umassmed.edu
Xin D. GaoPost-Doctoral Fellow, Harvard University/Broad InstituteVerifisert e-postadresse på broadinstitute.org
Jonathan PreallCold Spring Harbor LaboratoryVerifisert e-postadresse på cshl.edu
April PawlukScientific Publications StrategistVerifisert e-postadresse på arcinstitute.org
Kevin KimPostdoctoral Fellow, Harvard Medical SchoolVerifisert e-postadresse på genetics.med.harvard.edu
haiwei mouWistar InstituteVerifisert e-postadresse på wistar.org
Rodolphe BarrangouNorth Carolina State UniversityVerifisert e-postadresse på ncsu.edu
Zhiping WengProf & Chair, Department of Genomics and Computational Biology, UMASS Medical SchoolVerifisert e-postadresse på umassmed.edu
Jennifer DoudnaProfessor of Molecular and Cell Biology and Chemistry, UC BerkeleyVerifisert e-postadresse på berkeley.edu
Chun-Qing SongWestlake UniversityVerifisert e-postadresse på westlake.edu.cn
Dan WangAssistant Professor, RNA Therapeutics Institute & Gene Therapy Center, University of MassachusettsVerifisert e-postadresse på umassmed.edu
Rakhi RajanAssociate Professor -Chemistry and Biochemistry - University of OklahomaVerifisert e-postadresse på ou.edu
Daniel G. AndersonMassachusetts Institute of TechnologyVerifisert e-postadresse på mit.edu

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Erik Sontheimer

RNA Therapeutics Institute, UMass Medical School

Verifisert e-postadresse på umassmed.edu

RNA CRISPR gene regulation and editing


Tittel Sorter etter sitater Sorter etter år Sorter etter tittel	Sitert av Sitert av	År
Origins and mechanisms of miRNAs and siRNAs RW Carthew, EJ Sontheimer Cell 136 (4), 642-655, 2009	6287	2009
CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA LA Marraffini, EJ Sontheimer science 322 (5909), 1843-1845, 2008	2261	2008
Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways YS Lee, K Nakahara, JW Pham, K Kim, Z He, EJ Sontheimer, RW Carthew Cell 117 (1), 69-81, 2004	1756	2004
CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea LA Marraffini, EJ Sontheimer Nature Reviews Genetics 11 (3), 181-190, 2010	1360	2010
Self versus non-self discrimination during CRISPR RNA-directed immunity LA Marraffini, EJ Sontheimer Nature 463 (7280), 568-571, 2010	976	2010
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis Z Hou, Y Zhang, NE Propson, SE Howden, LF Chu, EJ Sontheimer, ... Proceedings of the National Academy of Sciences 110 (39), 15644-15649, 2013	943	2013
Assembly and function of RNA silencing complexes EJ Sontheimer Nature Reviews Molecular Cell Biology 6 (2), 127-138, 2005	630	2005
Target DNA interference with crRNA EJ Sontheimer, LA Marraffini US Patent App. 12/565,589, 2010	598	2010
A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila JW Pham, JL Pellino, YS Lee, RW Carthew, EJ Sontheimer Cell 117 (1), 83-94, 2004	592	2004
The U5 and U6 small nuclear RNAs as active site components of the spliceosome EJ Sontheimer, JA Steitz Science 262 (5142), 1989-1996, 1993	540	1993
Naturally occurring off-switches for CRISPR-Cas9 A Pawluk, N Amrani, Y Zhang, B Garcia, Y Hidalgo-Reyes, J Lee, A Edraki, ... Cell 167 (7), 1829-1838. e9, 2016	434	2016
Site-specific cross-linking of mammalian U5 snRNP to the 5'splice site before the first step of pre-mRNA splicing. JR Wyatt, EJ Sontheimer, JA Steitz Genes & Development 6 (12b), 2542-2553, 1992	415	1992
Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses D Wang, H Mou, S Li, Y Li, S Hough, K Tran, J Li, H Yin, DG Anderson, ... Human gene therapy 26 (7), 432-442, 2015	411	2015
Silencing by small RNAs is linked to endosomal trafficking YS Lee, S Pressman, AP Andress, K Kim, JL White, JJ Cassidy, X Li, ... Nature cell biology 11 (9), 1150-1156, 2009	395	2009
Silence from within: endogenous siRNAs and miRNAs EJ Sontheimer, RW Carthew Cell 122 (1), 9-12, 2005	391	2005
Processing-independent CRISPR RNAs limit natural transformation in Neisseria meningitidis Y Zhang, N Heidrich, BJ Ampattu, CW Gunderson, HS Seifert, C Schoen, ... Molecular cell 50 (4), 488-503, 2013	388	2013
A broad-spectrum inhibitor of CRISPR-Cas9 LB Harrington, KW Doxzen, E Ma, JJ Liu, GJ Knott, A Edraki, B Garcia, ... Cell 170 (6), 1224-1233. e15, 2017	289	2017
A compact, high-accuracy Cas9 with a dinucleotide PAM for in vivo genome editing A Edraki, A Mir, R Ibraheim, I Gainetdinov, Y Yoon, CQ Song, Y Cao, ... Molecular cell 73 (4), 714-726. e4, 2019	259	2019
Metal ion catalysis during splicing of premessenger RNA EJ Sontheimer, S Sun, JA Piccirilli Nature 388 (6644), 801-805, 1997	246	1997
Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice P Liu, SQ Liang, C Zheng, E Mintzer, YG Zhao, K Ponnienselvan, A Mir, ... Nature communications 12 (1), 2121, 2021	230	2021

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