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Richard Young
Richard Young
Professor of Biology, MIT
Verifisert e-postadresse på wi.mit.edu - Startside
Tittel
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Core transcriptional regulatory circuitry in human embryonic stem cells
LA Boyer, TI Lee, MF Cole, SE Johnstone, SS Levine, JP Zucker, ...
cell 122 (6), 947-956, 2005
55302005
Histone H3K27ac separates active from poised enhancers and predicts developmental state
MP Creyghton, AW Cheng, GG Welstead, T Kooistra, BW Carey, ...
Proceedings of the National Academy of Sciences 107 (50), 21931-21936, 2010
42372010
Transcriptional regulatory networks in Saccharomyces cerevisiae
TI Lee, NJ Rinaldi, F Robert, DT Odom, Z Bar-Joseph, GK Gerber, ...
science 298 (5594), 799-804, 2002
38312002
Master transcription factors and mediator establish super-enhancers at key cell identity genes
WA Whyte, DA Orlando, D Hnisz, BJ Abraham, CY Lin, MH Kagey, ...
Cell 153 (2), 307-319, 2013
36782013
Super-enhancers in the control of cell identity and disease
D Hnisz, BJ Abraham, TI Lee, A Lau, V Saint-André, AA Sigova, HA Hoke, ...
Cell 155 (4), 934-947, 2013
34112013
BET bromodomain inhibition as a therapeutic strategy to target c-Myc
JE Delmore, GC Issa, ME Lemieux, PB Rahl, J Shi, HM Jacobs, E Kastritis, ...
Cell 146 (6), 904-917, 2011
30362011
Polycomb complexes repress developmental regulators in murine embryonic stem cells
LA Boyer, K Plath, J Zeitlinger, T Brambrink, LA Medeiros, TI Lee, ...
nature 441 (7091), 349-353, 2006
30032006
Efficient isolation of genes by using antibody probes.
RA Young, RW Davis
Proceedings of the National Academy of Sciences 80 (5), 1194-1198, 1983
27581983
Selective inhibition of tumor oncogenes by disruption of super-enhancers
J Lovén, HA Hoke, CY Lin, A Lau, DA Orlando, CR Vakoc, JE Bradner, ...
Cell 153 (2), 320-334, 2013
27292013
Genome-wide location and function of DNA binding proteins
B Ren, F Robert, JJ Wyrick, O Aparicio, EG Jennings, I Simon, J Zeitlinger, ...
Science 290 (5500), 2306-2309, 2000
27032000
Control of developmental regulators by Polycomb in human embryonic stem cells
TI Lee, RG Jenner, LA Boyer, MG Guenther, SS Levine, RM Kumar, ...
Cell 125 (2), 301-313, 2006
26742006
Transcriptional regulatory code of a eukaryotic genome
CT Harbison, DB Gordon, TI Lee, NJ Rinaldi, KD Macisaac, TW Danford, ...
Nature 431 (7004), 99-104, 2004
26502004
Dissecting the regulatory circuitry of a eukaryotic genome
FCP Holstege, EG Jennings, JJ Wyrick, TI Lee, CJ Hengartner, MR Green, ...
Cell 95 (5), 717-728, 1998
23931998
A chromatin landmark and transcription initiation at most promoters in human cells
MG Guenther, SS Levine, LA Boyer, R Jaenisch, RA Young
Cell 130 (1), 77-88, 2007
22702007
Mediator and cohesin connect gene expression and chromatin architecture
MH Kagey, JJ Newman, S Bilodeau, Y Zhan, DA Orlando, NL van Berkum, ...
Nature 467 (7314), 430-435, 2010
21952010
Coactivator condensation at super-enhancers links phase separation and gene control
BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ...
Science 361 (6400), eaar3958, 2018
18022018
Genome-wide map of nucleosome acetylation and methylation in yeast
DK Pokholok, CT Harbison, S Levine, M Cole, NM Hannett, TI Lee, ...
Cell 122 (4), 517-527, 2005
17982005
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
R Jaenisch, R Young
Cell 132 (4), 567-582, 2008
17722008
Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study
D Nepogodiev, A Bhangu, JC Glasbey, E Li, OM Omar, JFF Simoes, ...
The Lancet 396 (10243), 27-38, 2020
17652020
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
A Marson, SS Levine, MF Cole, GM Frampton, T Brambrink, S Johnstone, ...
cell 134 (3), 521-533, 2008
17562008
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