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Simon Mitchell
Simon Mitchell
Reader in Cancer Research, Brighton and Sussex Medical School, University of Sussex
Verified email at bsms.ac.uk - Homepage
Title
Cited by
Cited by
Year
Signaling via the NFκB system
S Mitchell, J Vargas, A Hoffmann
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 8 (3), 227-241, 2016
9742016
Identification of neural oscillations and epileptiform changes in human brain organoids
RA Samarasinghe, OA Miranda, JE Buth, S Mitchell, I Ferando, ...
Nature neuroscience 24 (10), 1488-1500, 2021
1422021
A regulatory circuit controlling the dynamics of NFκB cRel transitions B cells from proliferation to plasma cell differentiation
K Roy, S Mitchell, Y Liu, S Ohta, Y Lin, MO Metzig, SL Nutt, A Hoffmann
Immunity 50 (3), 616-628. e6, 2019
682019
Nongenetic origins of cell-to-cell variability in B lymphocyte proliferation
S Mitchell, K Roy, TA Zangle, A Hoffmann
Proceedings of the National Academy of Sciences 115 (12), E2888-E2897, 2018
672018
Dissecting the regulatory strategies of NF-κB RelA target genes in the inflammatory response reveals differential transactivation logics
KA Ngo, K Kishimoto, J Davis-Turak, A Pimplaskar, Z Cheng, R Spreafico, ...
Cell reports 30 (8), 2758-2775. e6, 2020
432020
An NFκB activity calculator to delineate signaling crosstalk: type I and II interferons enhance NFκB via distinct mechanisms
S Mitchell, EL Mercado, QJ Cheng, G Ghosh, A Hoffmann
Frontiers in Immunology 10, 450667, 2019
422019
A computational model of liver iron metabolism
S Mitchell, P Mendes
PLoS computational biology 9 (11), e1003299, 2013
402013
Polypyrimidine tract-binding protein blocks miRNA-124 biogenesis to enforce its neuronal-specific expression in the mouse
KH Yeom, S Mitchell, AJ Linares, S Zheng, CH Lin, XJ Wang, A Hoffmann, ...
Proceedings of the National Academy of Sciences 115 (47), E11061-E11070, 2018
332018
TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target
E Kennedy, E Coulter, E Halliwell, N Profitos-Peleja, E Walsby, B Clark, ...
Blood, The Journal of the American Society of Hematology 137 (22), 3064-3078, 2021
252021
Neuronal network topology indicates distinct recovery processes after stroke
S Latifi, S Mitchell, R Habibey, F Hosseini, E Donzis, AM Estrada-Sánchez, ...
Cerebral Cortex 30 (12), 6363-6375, 2020
252020
Identifying noise sources governing cell-to-cell variability
S Mitchell, A Hoffmann
Current opinion in systems biology 8, 39-45, 2018
242018
An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF‐induced necroptosis decisions
M Oliver Metzig, Y Tang, S Mitchell, B Taylor, R Foreman, R Wollman, ...
Molecular systems biology 16 (12), e9677, 2020
192020
Identifying determinants of persistent MRSA bacteremia using mathematical modeling
T Mikkaichi, MR Yeaman, A Hoffmann, ...
PLoS computational biology 15 (7), e1007087, 2019
182019
Training the 21st century immunologist
R Spreafico, S Mitchell, A Hoffmann
Trends in immunology 36 (5), 283-285, 2015
162015
Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia
YL Chang, M Rossetti, DW Gjertson, L Rubbi, M Thompson, DJ Montoya, ...
Proceedings of the National Academy of Sciences 118 (10), e2000663118, 2021
132021
NF-kB and the CLL microenvironment
A O’Donnell, C Pepper, S Mitchell, A Pepper
Frontiers in Oncology 13, 1169397, 2023
92023
The NF-κB multidimer system model: A knowledge base to explore diverse biological contexts
S Mitchell, R Tsui, ZC Tan, A Pack, A Hoffmann
Science signaling 16 (776), eabo2838, 2023
82023
What will B will B: identifying molecular determinants of diverse B-cell fate decisions through systems biology
S Mitchell
Frontiers in Cell and Developmental Biology 8, 616592, 2021
82021
Studying NF-κB signaling with mathematical models
S Mitchell, R Tsui, A Hoffmann
NF-kappa B: Methods and Protocols, 647-661, 2015
82015
Elucidation of focal adhesion kinase as a modulator of migration and invasion and as a potential therapeutic target in chronic lymphocytic leukemia
TA Burley, A Hesketh, G Bucca, E Kennedy, EE Ladikou, BP Towler, ...
Cancers 14 (7), 1600, 2022
72022
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