| Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions AP Bracken, N Dietrich, D Pasini, KH Hansen, K Helin Genes & development 20 (9), 1123-1136, 2006 | 1528 | 2006 |
| EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer AP Bracken, D Pasini, M Capra, E Prosperini, E Colli, K Helin The EMBO journal 22 (20), 5323-5335, 2003 | 1449 | 2003 |
| Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity D Pasini, AP Bracken, MR Jensen, EL Denchi, K Helin The EMBO journal 23 (20), 4061-4071, 2004 | 1070 | 2004 |
| The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells AP Bracken, D Kleine-Kohlbrecher, N Dietrich, D Pasini, G Gargiulo, ... Genes & development 21 (5), 525-530, 2007 | 1025 | 2007 |
| E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis H Müller, AP Bracken, R Vernell, MC Moroni, F Christians, E Grassilli, ... Genes & development 15 (3), 267-285, 2001 | 937 | 2001 |
| A model for transmission of the H3K27me3 epigenetic mark KH Hansen, AP Bracken, D Pasini, N Dietrich, SS Gehani, A Monrad, ... Nature cell biology 10 (11), 1291-1300, 2008 | 819 | 2008 |
| The polycomb group protein Suz12 is required for embryonic stem cell differentiation D Pasini, AP Bracken, JB Hansen, M Capillo, K Helin Molecular and cellular biology 27 (10), 3769-3779, 2007 | 806 | 2007 |
| Polycomb group proteins: navigators of lineage pathways led astray in cancer AP Bracken, K Helin Nature Reviews Cancer 9 (11), 773-784, 2009 | 701 | 2009 |
| E2F target genes: unraveling the biology AP Bracken, M Ciro, A Cocito, K Helin Trends in biochemical sciences 29 (8), 409-417, 2004 | 674 | 2004 |
| H3K79 methylation profiles define murine and human MLL-AF4 leukemias AV Krivtsov, Z Feng, ME Lemieux, J Faber, S Vempati, AU Sinha, X Xia, ... Cancer cell 14 (5), 355-368, 2008 | 617 | 2008 |
| Retinoic acid expression associates with enhanced IL-22 production by γδ T cells and innate lymphoid cells and attenuation of intestinal inflammation LA Mielke, SA Jones, M Raverdeau, R Higgs, A Stefanska, JR Groom, ... Journal of Experimental Medicine 210 (6), 1117-1124, 2013 | 324 | 2013 |
| Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation GL Brien, G Gambero, DJ O'connell, E Jerman, SA Turner, CM Egan, ... Nature structural & molecular biology 19 (12), 1273-1281, 2012 | 275 | 2012 |
| Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription J Christensen, P Cloos, U Toftegaard, D Klinkenberg, AP Bracken, E Trinh, ... Nucleic acids research 33 (17), 5458-5470, 2005 | 229 | 2005 |
| PRC2 mediated H3K27 methylations in cellular identity and cancer E Conway, E Healy, AP Bracken Current opinion in cell biology 37, 42-48, 2015 | 220 | 2015 |
| Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A‐ARF locus N Dietrich, AP Bracken, E Trinh, CK Schjerling, H Koseki, J Rappsilber, ... The EMBO journal 26 (6), 1637-1648, 2007 | 213 | 2007 |
| PRC2. 1 and PRC2. 2 synergize to coordinate H3K27 trimethylation E Healy, M Mucha, E Glancy, DJ Fitzpatrick, E Conway, HK Neikes, ... Molecular cell 76 (3), 437-452. e6, 2019 | 158 | 2019 |
| The H3K36me2 methyltransferase Nsd1 demarcates PRC2-mediated H3K27me2 and H3K27me3 domains in embryonic stem cells G Streubel, A Watson, SG Jammula, A Scelfo, DJ Fitzpatrick, G Oliviero, ... Molecular cell 70 (2), 371-379. e5, 2018 | 156 | 2018 |
| Dangerous liaisons: interplay between SWI/SNF, NuRD, and Polycomb in chromatin regulation and cancer AP Bracken, GL Brien, CP Verrijzer Genes & development 33 (15-16), 936-959, 2019 | 139 | 2019 |
| CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression CM Egan, U Nyman, J Skotte, G Streubel, S Turner, DJ O’Connell, ... Developmental cell 26 (3), 223-236, 2013 | 139 | 2013 |
| A family of vertebrate-specific polycombs encoded by the LCOR/LCORL genes balance PRC2 subtype activities E Conway, E Jerman, E Healy, S Ito, D Holoch, G Oliviero, O Deevy, ... Molecular cell 70 (3), 408-421. e8, 2018 | 136 | 2018 |
Kristian HelinThe Institute of Cancer Research, ICRVerified email at icr.ac.uk
