Jasper Wouters
Jasper Wouters
Senior scientist disease bioinformatics @ Galapagos NV (Mechelen, Belgium)
Verified email at
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SCENIC: single-cell regulatory network inference and clustering
S Aibar, CB GonzŠlez-Blas, T Moerman, VA Huynh-Thu, H Imrichova, ...
Nature methods 14 (11), 1083-1086, 2017
Melanoma addiction to the long non-coding RNA SAMMSON
E Leucci, R Vendramin, M Spinazzi, P Laurette, M Fiers, J Wouters, ...
Nature 531 (7595), 518-522, 2016
Tumor vessel normalization by chloroquine independent of autophagy
H Maes, A Kuchnio, A Peric, S Moens, K Nys, K De Bock, A Quaegebeur, ...
Cancer cell 26 (2), 190-206, 2014
Keratin 19: a key role player in the invasion of human hepatocellular carcinomas
O Govaere, M Komuta, J Berkers, B Spee, C Janssen, F de Luca, ...
Gut 63 (4), 674-685, 2014
cisTopic: cis-regulatory topic modeling on single-cell ATAC-seq data
C Bravo GonzŠlez-Blas, L Minnoye, D Papasokrati, S Aibar, ...
Nature methods 16 (5), 397-400, 2019
Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching
L De Smedt, S Palmans, D Andel, O Govaere, B Boeckx, D Smeets, ...
British journal of cancer 116 (1), 58-65, 2017
The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes
J Jacobs, M Atkins, K Davie, H Imrichova, L Romanelli, V Christiaens, ...
Nature genetics 50 (7), 1011-1020, 2018
Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche
O Govaere, J Wouters, M Petz, YP Vandewynckel, K Van den Eynde, ...
Journal of hepatology 64 (3), 609-617, 2016
Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma
J Wouters, Z Kalender-Atak, L Minnoye, KI Spanier, M De Waegeneer, ...
Nature Cell Biology 22 (8), 986-998, 2020
Antitumor Immunity Triggered by Melphalan Is Potentiated by Melanoma Cell Surface–Associated CalreticulinMelphalan, Antimelanoma Immunity, Inflammation
AM Dudek-Perić, GB Ferreira, A Muchowicz, J Wouters, N Prada, S Martin, ...
Cancer research 75 (8), 1603-1614, 2015
Human pancreatic cancer contains a side population expressing cancer stem cell-associated and prognostic genes
A Van den broeck, H Vankelecom, W Van Delm, L Gremeaux, J Wouters, ...
PloS one 8 (9), e73968, 2013
Comprehensive DNA methylation study identifies novel progression-related and prognostic markers for cutaneous melanoma
J Wouters, M Vizoso, A Martinez-Cardus, FJ Carmona, O Govaere, ...
BMC medicine 15 (1), 1-16, 2017
The PDGFRα-laminin B1-keratin 19 cascade drives tumor progression at the invasive front of human hepatocellular carcinoma
O Govaere, M Petz, J Wouters, YP Vandewynckel, EJ Scott, B Topal, ...
Oncogene 36 (47), 6605-6616, 2017
The human melanoma side population displays molecular and functional characteristics of enriched chemoresistance and tumorigenesis
J Wouters, M Stas, L Gremeaux, O Govaere, A Van den Broeck, H Maes, ...
PLoS One 8 (10), e76550, 2013
Cross-species analysis of enhancer logic using deep learning
L Minnoye, II Taskiran, D Mauduit, M Fazio, L Van Aerschot, ...
Genome research 30 (12), 1815-1834, 2020
The effect of L-PRF membranes on bone healing in rabbit tibiae bone defects: micro-CT and biomarker results
F Faot, S Deprez, K Vandamme, GV Camargos, N Pinto, J Wouters, ...
Scientific reports 7 (1), 1-10, 2017
Plasma cells in primary melanoma. Prognostic significance and possible role of IgA
FM Bosisio, JS Wilmott, N Volders, M Mercier, J Wouters, M Stas, ...
Modern Pathology 29 (4), 347-358, 2016
The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype
N Vandamme, G Denecker, K Bruneel, G Blancke, ÷ Akay, J Taminau, ...
Cancer research 80 (14), 2983-2995, 2020
Epithelial‐mesenchymal transition during invasion of cutaneous squamous cell carcinoma is paralleled by AKT activation
K Barrette, S Van Kelst, J Wouters, V Marasigan, S Fieuws, P Agostinis, ...
British Journal of Dermatology 171 (5), 1014-1021, 2014
High‐throughput sequencing identifies aetiology‐dependent differences in ductular reaction in human chronic liver disease
O Govaere, S Cockell, M Van Haele, J Wouters, W Van Delm, ...
The Journal of pathology 248 (1), 66-76, 2019
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