Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants P Cassina, A Cassina, M Pehar, R Castellanos, M Gandelman, A De León, ... Journal of Neuroscience 28 (16), 4115-4122, 2008 | 374 | 2008 |
Extracellular ATP and the P2X7receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis M Gandelman, H Peluffo, JS Beckman, P Cassina, L Barbeito Journal of neuroinflammation 7, 1-9, 2010 | 163 | 2010 |
Modulation of astrocytic mitochondrial function by dichloroacetate improves survival and motor performance in inherited amyotrophic lateral sclerosis E Miquel, A Cassina, L Martínez-Palma, C Bolatto, E Trías, M Gandelman, ... PloS one 7 (4), e34776, 2012 | 126 | 2012 |
Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice KA Trumbull, D McAllister, MM Gandelman, WY Fung, T Lew, L Brennan, ... Neurobiology of disease 45 (1), 137-144, 2012 | 61 | 2012 |
P2X7 receptor‐induced death of motor neurons by a peroxynitrite/FAS‐dependent pathway M Gandelman, M Levy, P Cassina, L Barbeito, JS Beckman Journal of neurochemistry 126 (3), 382-388, 2013 | 60 | 2013 |
Nogo receptor antagonizes p75NTR-dependent motor neuron death L Dupuis, M Pehar, P Cassina, F Rene, R Castellanos, C Rouaux, ... Proceedings of the National Academy of Sciences 105 (2), 740-745, 2008 | 48 | 2008 |
Staufen1 in human neurodegeneration S Paul, W Dansithong, KP Figueroa, M Gandelman, DR Scoles, SM Pulst Annals of neurology 89 (6), 1114-1128, 2021 | 29 | 2021 |
Staufen 1 amplifies proapoptotic activation of the unfolded protein response M Gandelman, W Dansithong, KP Figueroa, S Paul, DR Scoles, SM Pulst Cell Death & Differentiation 27 (10), 2942-2951, 2020 | 24 | 2020 |
Consensus paper: strengths and weaknesses of animal models of spinocerebellar ataxias and their clinical implications J Cendelin, M Cvetanovic, M Gandelman, H Hirai, HT Orr, SM Pulst, ... The Cerebellum 21 (3), 452-481, 2022 | 22 | 2022 |
ALS-associated genes in SCA2 mouse spinal cord transcriptomes DR Scoles, W Dansithong, LT Pflieger, S Paul, M Gandelman, ... Human molecular genetics 29 (10), 1658-1672, 2020 | 18 | 2020 |
The AKT modulator A-443654 reduces α-synuclein expression and normalizes ER stress and autophagy M Gandelman, W Dansithong, SC Kales, S Paul, G Maag, E Aoyama, ... Journal of Biological Chemistry 297 (4), 2021 | 11 | 2021 |
Staufen impairs autophagy in neurodegeneration S Paul, W Dansithong, M Gandelman, KP Figueroa, T Zu, LPW Ranum, ... Annals of neurology 93 (2), 398-416, 2023 | 9 | 2023 |
Staufen blocks autophagy in neurodegeneration S Paul, W Dansithong, M Gandelman, KP Figueroa, T Zu, LPW Ranum, ... bioRxiv, 659649, 2019 | 5 | 2019 |
Slc9a6 mutation causes Purkinje cell loss and ataxia in the shaker rat KP Figueroa, CJ Anderson, S Paul, W Dansithong, M Gandelman, ... Human Molecular Genetics 32 (10), 1647-1659, 2023 | 3 | 2023 |
GGC expansion in ZFHX3 causes SCA4 and impairs autophagy KP Figueroa, C Gross, EB Atienza, S Paul, M Gandelman, TB Haack, ... medRxiv, 2023.10. 26.23297560, 2023 | 3 | 2023 |
A Multivitamin Mixture Protects against Oxidative Stress-Mediated Telomere Shortening MA Levy, J Tian, M Gandelman, H Cheng, M Tsapekos, SR Crego, ... Journal of Dietary Supplements 21 (1), 53-70, 2024 | 2 | 2024 |
A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2 DR Scoles, M Gandelman, S Paul, T Dexheimer, W Dansithong, ... Journal of Biological Chemistry 298 (8), 2022 | 2 | 2022 |
A GGC-repeat expansion in ZFHX3 encoding polyglycine causes spinocerebellar ataxia type 4 and impairs autophagy KP Figueroa, C Gross, E Buena-Atienza, S Paul, M Gandelman, N Kakar, ... Nature Genetics, 1-10, 2024 | | 2024 |
Cerebellar Micro-RNA Profile in a Mouse Model of Spinocerebellar Ataxia Type 2 S Paul, W Dansithong, M Gandelman, KP Figueroa, DR Scoles, SM Pulst Neurology: Genetics 10 (2), e200144, 2024 | | 2024 |
Targeting Staufen 1 with antisense oligonucleotides for treating ALS and SCA2 DR Scoles, S Paul, W Dansithong, KP Figueroa, M Gandelman, F Royzen, ... bioRxiv, 2022.11. 16.516816, 2022 | | 2022 |