Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure RJ Van Oort, MD McCauley, SS Dixit, L Pereira, Y Yang, JL Respress, ... Circulation 122 (25), 2669-2679, 2010 | 346 | 2010 |
Kinetics of FKBP12. 6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks T Guo, RL Cornea, S Huke, E Camors, Y Yang, E Picht, BR Fruen, ... Circulation research 106 (11), 1743-1752, 2010 | 197 | 2010 |
Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants HS Hwang, FR Nitu, Y Yang, K Walweel, L Pereira, CN Johnson, ... Circulation research 114 (7), 1114-1124, 2014 | 159 | 2014 |
Oxidation of ryanodine receptor (RyR) and calmodulin enhance Ca release and pathologically alter, RyR structure and calmodulin affinity T Oda, Y Yang, H Uchinoumi, DD Thomas, Y Chen-Izu, T Kato, ... Journal of molecular and cellular cardiology 85, 240-248, 2015 | 113 | 2015 |
CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift H Uchinoumi, Y Yang, T Oda, N Li, KM Alsina, JL Puglisi, Y Chen-Izu, ... Journal of molecular and cellular cardiology 98, 62-72, 2016 | 97 | 2016 |
Cardiac myocyte Z-line calmodulin is mainly RyR2-bound, and reduction is arrhythmogenic and occurs in heart failure Y Yang, T Guo, T Oda, A Chakraborty, L Chen, H Uchinoumi, ... Circulation research 114 (2), 295-306, 2014 | 91 | 2014 |
Size matters: ryanodine receptor cluster size affects arrhythmogenic sarcoplasmic reticulum calcium release S Galice, Y Xie, Y Yang, D Sato, DM Bers Journal of the American Heart Association 7 (13), e008724, 2018 | 82 | 2018 |
Effect of Zinc Supplementation on Maintenance Hemodialysis Patients: A Systematic Review and Meta‐Analysis of 15 Randomized Controlled Trials LJ Wang, MQ Wang, R Hu, Y Yang, YS Huang, SX Xian, L Lu BioMed Research International 2017 (1), 1024769, 2017 | 67 | 2017 |
FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel T Guo, BR Fruen, FR Nitu, TD Nguyen, Y Yang, RL Cornea, DM Bers Biophysical journal 101 (9), 2170-2177, 2011 | 45 | 2011 |
Antimicrobial activity, membrane interaction and stability of the D-amino acid substituted analogs of antimicrobial peptide W3R6 Y Li, T Liu, Y Liu, Z Tan, Y Ju, Y Yang, W Dong Journal of Photochemistry and Photobiology B: Biology 200, 111645, 2019 | 42 | 2019 |
Size matters: ryanodine receptor cluster size heterogeneity potentiates calcium waves Y Xie, Y Yang, S Galice, DM Bers, D Sato Biophysical journal 116 (3), 530-539, 2019 | 39 | 2019 |
In cardiomyocytes, binding of unzipping peptide activates ryanodine receptor 2 and reciprocally inhibits calmodulin binding T Oda, Y Yang, FR Nitu, B Svensson, X Lu, BR Fruen, RL Cornea, ... Circulation research 112 (3), 487-497, 2013 | 31 | 2013 |
FRET-based trilateration of probes bound within functional ryanodine receptors B Svensson, T Oda, FR Nitu, Y Yang, I Cornea, Y Chen-Izu, ... Biophysical journal 107 (9), 2037-2048, 2014 | 14 | 2014 |
De 458 Almeida AC, Skapura DG, Anderson ME, Bers DM, and Wehrens XH RJ van Oort, MD McCauley, SS Dixit, L Pereira, Y Yang, JL Respress, ... Ryanodine receptor 459, 2669-2679, 0 | 12 | |
Long non-coding RNA N1LR protects against myocardial ischemic/reperfusion injury through regulating the TGF-β signaling pathway L Du, J Chen, Y Wu, G Xia, M Chen, P Zhao, Y Wang, D Yao, F Liu, ... Frontiers in cardiovascular medicine 8, 654969, 2021 | 9 | 2021 |
Ryanodine receptor phosphorylation by CaMKII promotes life-threatening ventricular arrhythmias in mice with heart failure RJ van Oort, MD McCauley, SS Dixit, L Pereira, Y Yang, JL Respress, ... Circulation 122 (25), 2669, 2010 | 7 | 2010 |
Binding of RyR2 “unzipping” peptide in cardiomyocytes activates RyR2 and reciprocally inhibits calmodulin binding T Oda, Y Yang, FR Nitu, B Svensson, X Lu, BR Fruen, RL Cornea, ... Circulation research 112 (3), 487, 2013 | 3 | 2013 |
In situ measurement of RyR2-calmodulin binding in permeabilized cardiomyocytes Y Yang, A Chakraborty, T Guo, RL Cornea, G Meissner, DM Bers Biophysical Journal 100 (3), 413a-414a, 2011 | 2 | 2011 |
Calmodulin mutations in human genetic arrhythmia disorders exhibit divergent functional effects on ryanodine receptor Ca release channels HS Hwang, FR Nitu, Y Yang, CN Johnson, M Faggioni, WJ Chazin, ... Circulation 128 (suppl_22), A14157-A14157, 2013 | 1 | 2013 |
RyR2-R4496C C-Terminal Cpvt Mutation Causes Calcium Leak Independent of Calmodulin-Ryr2 Affinity H Uchinoumi, X Dong, I Stefanon, Y Yang, M Said, R Faustino, RL Cornea, ... Circulation 138 (Suppl_1), A12949-A12949, 2018 | | 2018 |