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David Lye
David Lye
National Centre for Infectious Diseases; Tan Tock Seng Hospital; Lee Kong Chian School of Medicine
Verified email at ttsh.com.sg
Title
Cited by
Cited by
Year
Remdesivir for the treatment of Covid-19
JH Beigel, KM Tomashek, LE Dodd, AK Mehta, BS Zingman, AC Kalil, ...
New England Journal of Medicine 383 (19), 1813-1826, 2020
54042020
Remdesivir for the treatment of Covid-19—preliminary report
JH Beigel, KM Tomashek, LE Dodd, AK Mehta, BS Zingman, AC Kalil, ...
New England Journal of Medicine 383 (19), 1813-1836, 2020
24622020
Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore
BE Young, SWX Ong, S Kalimuddin, JG Low, SY Tan, J Loh, OT Ng, ...
Jama 323 (15), 1488-1494, 2020
24492020
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ...
Science 370 (6515), eabd4585, 2020
21962020
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ...
Science 370 (6515), eabd4570, 2020
19102020
Baricitinib plus remdesivir for hospitalized adults with Covid-19
AC Kalil, TF Patterson, AK Mehta, KM Tomashek, CR Wolfe, V Ghazaryan, ...
New England Journal of Medicine 384 (9), 795-807, 2021
15842021
Remdesivir for 5 or 10 days in patients with severe Covid-19
JD Goldman, DCB Lye, DS Hui, KM Marks, R Bruno, R Montejano, ...
New England Journal of Medicine 383 (19), 1827-1837, 2020
15272020
Effect of remdesivir vs standard care on clinical status at 11 days in patients with moderate COVID-19: a randomized clinical trial
CD Spinner, RL Gottlieb, GJ Criner, JRA López, AM Cattelan, ...
Jama 324 (11), 1048-1057, 2020
13362020
A SARS-CoV-2 surrogate virus neutralization test based on antibody-mediated blockage of ACE2–spike protein–protein interaction
CW Tan, WN Chia, X Qin, P Liu, MIC Chen, C Tiu, Z Hu, VCW Chen, ...
Nature biotechnology 38 (9), 1073-1078, 2020
10422020
Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail
J Hansen, A Baum, KE Pascal, V Russo, S Giordano, E Wloga, BO Fulton, ...
Science 369 (6506), 1010-1014, 2020
9172020
Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients
PY Chia, KK Coleman, YK Tan, SWX Ong, M Gum, SK Lau, XF Lim, ...
Nature communications 11 (1), 1-7, 2020
8532020
Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures
R Pung, CJ Chiew, BE Young, S Chin, MIC Chen, HE Clapham, AR Cook, ...
The Lancet 395 (10229), 1039-1046, 2020
7402020
Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients
AT Tan, M Linster, CW Tan, N Le Bert, WN Chia, K Kunasegaran, ...
Cell reports 34 (6), 2021
5642021
Effect of piperacillin-tazobactam vs meropenem on 30-day mortality for patients with E coli or Klebsiella pneumoniae bloodstream infection and ceftriaxone resistance: a …
PNA Harris, PA Tambyah, DC Lye, Y Mo, TH Lee, M Yilmaz, TH Alenazi, ...
Jama 320 (10), 984-994, 2018
5552018
Assessing viral shedding and infectivity of tears in coronavirus disease 2019 (COVID-19) patients
IYJ Seah, DE Anderson, AEZ Kang, L Wang, P Rao, BE Young, DC Lye, ...
Ophthalmology 127 (7), 977-979, 2020
5132020
Antimicrobial consumption and resistance in adult hospital inpatients in 53 countries: results of an internet-based global point prevalence survey
A Versporten, P Zarb, I Caniaux, MF Gros, N Drapier, M Miller, V Jarlier, ...
The Lancet Global Health 6 (6), e619-e629, 2018
4962018
Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study
BE Young, SW Fong, YH Chan, TM Mak, LW Ang, DE Anderson, CYP Lee, ...
The lancet 396 (10251), 603-611, 2020
4382020
Evaluation of the effectiveness of surveillance and containment measures for the first 100 patients with COVID-19 in Singapore—January 2–February 29, 2020
Y Ng, Z Li, YX Chua, WL Chaw, Z Zhao, B Er, R Pung, CJ Chiew, DC Lye, ...
Morbidity and mortality weekly report 69 (11), 307, 2020
3642020
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ...
Science immunology 6 (62), eabl4340, 2021
3552021
Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study
PY Chia, SWX Ong, CJ Chiew, LW Ang, JM Chavatte, TM Mak, L Cui, ...
Clinical microbiology and infection 28 (4), 612. e1-612. e7, 2022
3542022
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