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Stephen H. Tsang
Stephen H. Tsang
Verifisert e-postadresse på columbia.edu
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Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2
S Ortega, M Ittmann, SH Tsang, M Ehrlich, C Basilico
Proceedings of the National Academy of Sciences 95 (10), 5672-5677, 1998
7801998
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes
JK White, AK Gerdin, NA Karp, E Ryder, M Buljan, JN Bussell, J Salisbury, ...
Cell 154 (2), 452-464, 2013
5192013
Unexpected mutations after CRISPR–Cas9 editing in vivo
KA Schaefer, WH Wu, DF Colgan, SH Tsang, AG Bassuk, VB Mahajan
Nature methods 14 (6), 547-548, 2017
4622017
A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases
S Yamamoto, M Jaiswal, WL Charng, T Gambin, E Karaca, G Mirzaa, ...
Cell 159 (1), 200-214, 2014
3992014
Allele-specific chromosome removal after Cas9 cleavage in human embryos
MV Zuccaro, J Xu, C Mitchell, D Marin, R Zimmerman, B Rana, ...
Cell 183 (6), 1650-1664. e15, 2020
2482020
Role for the target enzyme in deactivation of photoreceptor G protein in vivo
SH Tsang, ME Burns, PD Calvert, P Gouras, DA Baylor, SP Goff, ...
Science 282 (5386), 117-121, 1998
2281998
Viral delivery systems for CRISPR
CL Xu, MZC Ruan, VB Mahajan, SH Tsang
Viruses 11 (1), 28, 2019
2162019
Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia
S Kohl, D Zobor, WC Chiang, N Weisschuh, J Staller, IG Menendez, ...
Nature genetics 47 (7), 757-765, 2015
2162015
Retinal degeneration in mice lacking the γ subunit of the rod cGMP phosphodiesterase
SH Tsang, P Gouras, CK Yamashita, H Kjeldbye, J Fisher, DB Farber, ...
Science 272 (5264), 1026-1029, 1996
2141996
Long-term safety and efficacy of human-induced pluripotent stem cell (iPS) grafts in a preclinical model of retinitis pigmentosa
Y Li, YT Tsai, CW Hsu, D Erol, J Yang, WH Wu, RJ Davis, D Egli, ...
Molecular medicine 18, 1312-1319, 2012
2082012
Precision medicine: genetic repair of retinitis pigmentosa in patient-derived stem cells
AG Bassuk, A Zheng, Y Li, SH Tsang, VB Mahajan
Scientific reports 6 (1), 19969, 2016
2012016
Quantitative fundus autofluorescence in recessive Stargardt disease
TR Burke, T Duncker, RL Woods, JP Greenberg, J Zernant, SH Tsang, ...
Investigative ophthalmology & visual science 55 (5), 2841-2852, 2014
1862014
Frequent hypomorphic alleles account for a significant fraction of ABCA4 disease and distinguish it from age-related macular degeneration
J Zernant, W Lee, FT Collison, GA Fishman, YV Sergeev, K Schuerch, ...
Journal of medical genetics 54 (6), 404-412, 2017
1802017
Analysis of the ABCA4 gene by next-generation sequencing
J Zernant, C Schubert, KM Im, T Burke, CM Brown, GA Fishman, ...
Investigative ophthalmology & visual science 52 (11), 8479-8487, 2011
1702011
A comparison of fundus autofluorescence and retinal structure in patients with Stargardt disease
NL Gomes, VC Greenstein, JN Carlson, SH Tsang, RT Smith, RE Carr, ...
Investigative ophthalmology & visual science 50 (8), 3953-3959, 2009
1522009
Analysis of the ABCA4 genomic locus in Stargardt disease
J Zernant, Y Xie, C Ayuso, R Riveiro-Alvarez, MA Lopez-Martinez, ...
Human molecular genetics 23 (25), 6797-6806, 2014
1482014
Safety and vision outcomes of subretinal gene therapy targeting cone photoreceptors in achromatopsia: a nonrandomized controlled trial
MD Fischer, S Michalakis, B Wilhelm, D Zobor, R Muehlfriedel, S Kohl, ...
JAMA ophthalmology 138 (6), 643-651, 2020
1352020
Effects of extracellular matrix and neighboring cells on induction of human embryonic stem cells into retinal or retinal pigment epithelial progenitors
J Gong, O Sagiv, H Cai, SH Tsang, LV Del Priore
Experimental eye research 86 (6), 957-965, 2008
1322008
Gene therapy and genome surgery in the retina
JE DiCarlo, VB Mahajan, SH Tsang
The Journal of clinical investigation 128 (6), 2177-2188, 2018
1312018
Differentiation of hypothalamic-like neurons from human pluripotent stem cells
L Wang, K Meece, DJ Williams, KA Lo, M Zimmer, G Heinrich, JM Carli, ...
The Journal of clinical investigation 125 (2), 796-808, 2015
1272015
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