Metaplasia: tissue injury adaptation and a precursor to the dysplasia–cancer sequence V Giroux, AK Rustgi Nature Reviews Cancer 17 (10), 594-604, 2017 | 309 | 2017 |
Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma M Natsuizaka, KA Whelan, S Kagawa, K Tanaka, V Giroux, ... Nature communications 8 (1), 1758, 2017 | 192 | 2017 |
Loss of stromal IMP1 promotes a tumorigenic microenvironment in the colon KE Hamilton, P Chatterji, ET Lundsmith, SF Andres, V Giroux, PD Hicks, ... Molecular cancer research 13 (11), 1478-1486, 2015 | 139 | 2015 |
Three-dimensional organoids reveal therapy resistance of esophageal and oropharyngeal squamous cell carcinoma cells T Kijima, H Nakagawa, M Shimonosono, PM Chandramouleeswaran, ... Cellular and molecular gastroenterology and hepatology 7 (1), 73-91, 2019 | 121 | 2019 |
The esophageal organoid system reveals functional interplay between notch and cytokines in reactive epithelial changes Y Kasagi, PM Chandramouleeswaran, KA Whelan, K Tanaka, V Giroux, ... Cellular and molecular gastroenterology and hepatology 5 (3), 333-352, 2018 | 100 | 2018 |
Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration V Giroux, AA Lento, M Islam, JR Pitarresi, A Kharbanda, KE Hamilton, ... The Journal of clinical investigation 127 (6), 2378-2391, 2017 | 100 | 2017 |
Estrogen receptor β deficiency enhances small intestinal tumorigenesis in ApcMin/+ mice V Giroux, F Lemay, G Bernatchez, Y Robitaille, JC Carrier International journal of cancer 123 (2), 303-311, 2008 | 92 | 2008 |
Integrin α6A splice variant regulates proliferation and the Wnt/β-catenin pathway in human colorectal cancer cells JF Groulx, V Giroux, M Beauséjour, S Boudjadi, N Basora, JC Carrier, ... Carcinogenesis 35 (6), 1217-1227, 2014 | 88 | 2014 |
WNT10A promotes an invasive and self-renewing phenotype in esophageal squamous cell carcinoma A Long, V Giroux, KA Whelan, KE Hamilton, MP Tétreault, K Tanaka, ... Carcinogenesis 36 (5), 598-606, 2015 | 76 | 2015 |
Generation and characterization of patient‐derived head and neck, oral, and esophageal cancer organoids TA Karakasheva, T Kijima, M Shimonosono, H Maekawa, V Sahu, ... Current Protocols in Stem Cell Biology 53 (1), e109, 2020 | 63 | 2020 |
ERRα metabolic nuclear receptor controls growth of colon cancer cells G Bernatchez, V Giroux, T Lassalle, AC Carpentier, N Rivard, JC Carrier Carcinogenesis 34 (10), 2253-2261, 2013 | 60 | 2013 |
Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4 ME Vega, V Giroux, M Natsuizaka, M Liu, AJ Klein-Szanto, DB Stairs, ... Cell Cycle 13 (24), 3857-3866, 2014 | 56 | 2014 |
Autophagy mediates epithelial cytoprotection in eosinophilic oesophagitis KA Whelan, JF Merves, V Giroux, K Tanaka, A Guo, ... Gut 66 (7), 1197-1207, 2017 | 54 | 2017 |
Chemopreventive effect of ERβ‐Selective agonist on intestinal tumorigenesis in ApcMin/+ Mice V Giroux, G Bernatchez, JC Carrier Molecular carcinogenesis 50 (5), 359-369, 2011 | 47 | 2011 |
Mouse intestinal Krt15+ crypt cells are radio-resistant and tumor initiating V Giroux, J Stephan, P Chatterji, B Rhoades, EP Wileyto, AJ Klein-Szanto, ... Stem Cell Reports 10 (6), 1947-1958, 2018 | 37 | 2018 |
Posttranscriptional regulation of colonic epithelial repair by RNA binding protein IMP 1/IGF 2 BP 1 P Chatterji, PA Williams, KA Whelan, FC Samper, SF Andres, LA Simon, ... EMBO reports 20 (6), e47074, 2019 | 25 | 2019 |
Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three‐Dimensional Esophageal Organoids H Nakagawa, Y Kasagi, TA Karakasheva, T Hara, B Aaron, ... Current protocols in stem cell biology 52 (1), e106, 2020 | 24 | 2020 |
Rab11‐FIP1 mediates epithelial‐mesenchymal transition and invasion in esophageal cancer Q Tang, A Lento, K Suzuki, G Efe, T Karakasheva, A Long, V Giroux, ... EMBO reports 22 (2), e48351, 2021 | 15 | 2021 |
HNF4α acts as upstream functional regulator of intestinal Wnt3 and paneth cell fate C Jones, M Avino, V Giroux, F Boudreau Cellular and Molecular Gastroenterology and Hepatology 15 (3), 593-612, 2023 | 7 | 2023 |
Demystifying the differences between tumor-initiating cells and cancer stem cells in colon cancer P Chatterji, J Douchin, V Giroux Current Colorectal Cancer Reports 14, 242-250, 2018 | 7 | 2018 |