| Evidence for irreversible inhibition of glycogen synthase kinase-3β by tideglusib JM Domínguez, A Fuertes, L Orozco, M del Monte-Millán, E Delgado, ... Journal of Biological Chemistry 287 (2), 893-904, 2012 | 253 | 2012 |
| Sordarins: a new class of antifungals with selective inhibition of the protein synthesis elongation cycle in yeasts JM Domínguez, VA Kelly, OS Kinsman, MS Marriott, ... Antimicrobial Agents and Chemotherapy 42 (9), 2274-2278, 1998 | 156 | 1998 |
| Identification of Elongation Factor 2 as the Essential Protein Targeted by Sordarins in Candida albicans JM Domínguez, JJ Martín Antimicrobial Agents and Chemotherapy 42 (9), 2279-2283, 1998 | 133 | 1998 |
| Translation elongation factor eEF1A2 is a novel anticancer target for the marine natural product plitidepsin A Losada, MJ Muñoz-Alonso, C García, PA Sánchez-Murcia, ... Scientific reports 6 (1), 35100, 2016 | 84 | 2016 |
| Mode of action of endoglucanase III from Trichoderma reesei R Macarron, C Acebal, MP Castillon, JM Dominguez, I De la Mata, ... Biochemical Journal 289 (3), 867-873, 1993 | 84 | 1993 |
| Sordarin inhibits fungal protein synthesis by blocking translocation differently to fusidic acid JM Domı́nguez, MG Gómez-Lorenzo, JJ Martı́n Journal of Biological Chemistry 274 (32), 22423-22427, 1999 | 75 | 1999 |
| Discovery of GSK837149A, an inhibitor of human fatty acid synthase targeting the β‐ketoacyl reductase reaction MJ Vázquez, W Leavens, R Liu, B Rodríguez, M Read, S Richards, ... The FEBS journal 275 (7), 1556-1567, 2008 | 72 | 2008 |
| Structure-based optimization of oxadiazole-based GSK-3 inhibitors FL Monte, T Kramer, J Gu, M Brodrecht, J Pilakowski, A Fuertes, ... European journal of medicinal chemistry 61, 26-40, 2013 | 61 | 2013 |
| Identification of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase-3α F Lo Monte, T Kramer, J Gu, UR Anumala, L Marinelli, V La Pietra, ... Journal of medicinal chemistry 55 (9), 4407-4424, 2012 | 61 | 2012 |
| Binding of eEF1A2 to the RNA-dependent protein kinase PKR modulates its activity and promotes tumour cell survival A Losada, MJ Muñoz-Alonso, M Martínez-Díez, F Gago, JM Domínguez, ... British journal of cancer 119 (11), 1410-1420, 2018 | 34 | 2018 |
| Synthesis and biological evaluation of glycogen synthase kinase 3 (GSK-3) inhibitors: An fast and atom efficient access to 1-aryl-3-benzylureas FL Monte, T Kramer, A Boländer, B Plotkin, H Eldar-Finkelman, A Fuertes, ... Bioorganic & medicinal chemistry letters 21 (18), 5610-5615, 2011 | 31 | 2011 |
| Mechanisms of thermoinactivation of endoglucanase I from Trichoderma reesei QM 9414 JM Dominguez, C Acebal, J Jimenez, I De La Mata, R Macarron, ... Biochemical journal 287 (2), 583-588, 1992 | 28 | 1992 |
| Kinetic mechanism of β-glucosidase from Trichoderma reesei QM 9414 P Estrada, I Mata, JM Dominguez, MP Castillón, C Acebal Biochimica et Biophysica Acta (BBA)-General Subjects 1033 (3), 298-304, 1990 | 25 | 1990 |
| Chemical Modification of β-Glucosidase from Trichoderma reesei QM 9414 M Isabel de la, MP Castillón, JM Domínguez, R Macarrón, C Acebal The Journal of Biochemistry 114 (5), 754-759, 1993 | 23 | 1993 |
| Thermoinactivation of cellobiohydrolase I from Trichoderma reesei QM 9414 J Jiménez, JM Domínguez, MP Castillón, C Acebal Carbohydrate research 268 (2), 257-266, 1995 | 19 | 1995 |
| Chemical mechanism of β-glucosidase from Trichoderma reesei QM 9414. pH-dependence of kinetic parameters I De La Mata, P Estrada, R Macarrón, JM Dominguez, MP Castillón, ... Biochemical journal 283 (3), 679-682, 1992 | 19 | 1992 |
| Thermally denatured BSA, a surrogate additive to replace BSA in buffers for high-throughput screening I Peña, JM Domínguez Journal of biomolecular screening 15 (10), 1281-1286, 2010 | 18 | 2010 |
| CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110 JM Domínguez, G Pérez-Chacón, MJ Guillén, MJ Muñoz-Alonso, ... Journal of Hematology & Oncology 13, 1-15, 2020 | 17 | 2020 |
| Self-assembling hybrid linear-dendritic block copolymers: The design of nano-carriers for lipophilic antitumoral drugs E Fedeli, A Lancelot, JM Dominguez, JL Serrano, P Calvo, T Sierra Nanomaterials 9 (2), 161, 2019 | 17 | 2019 |
| MI130004, a novel antibody–drug conjugate combining trastuzumab with a molecule of marine origin, shows outstanding In Vivo activity against HER2-expressing tumors P Avilés, JM Domínguez, MJ Guillén, MJ Muñoz-Alonso, C Mateo, ... Molecular cancer therapeutics 17 (4), 786-794, 2018 | 17 | 2018 |
