An extended transcriptional network for pluripotency of embryonic stem cells J Kim, J Chu, X Shen, J Wang, SH Orkin Cell 132 (6), 1049-1061, 2008 | 1563 | 2008 |
A protein interaction network for pluripotency of embryonic stem cells J Wang, S Rao, J Chu, X Shen, DN Levasseur, TW Theunissen, SH Orkin Nature 444 (7117), 364-368, 2006 | 1324 | 2006 |
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response K Lee, W Tirasophon, X Shen, M Michalak, R Prywes, T Okada, ... Genes & development 16 (4), 452-466, 2002 | 1274 | 2002 |
EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency X Shen, Y Liu, YJ Hsu, Y Fujiwara, J Kim, X Mao, GC Yuan, SH Orkin Molecular cell 32 (4), 491-502, 2008 | 1089 | 2008 |
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response K Zhang, X Shen, J Wu, K Sakaki, T Saunders, DT Rutkowski, SH Back, ... Cell 124 (3), 587-599, 2006 | 936 | 2006 |
Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development X Shen, RE Ellis, K Lee, CY Liu, K Yang, A Solomon, H Yoshida, ... Cell 107 (7), 893-903, 2001 | 824 | 2001 |
The unfolded protein response in nutrient sensing and differentiation RJ Kaufman, D Scheuner, M Schröder, X Shen, K Lee, CY Liu, SM Arnold Nature reviews Molecular cell biology 3 (6), 411-421, 2002 | 791 | 2002 |
Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation BG Wilson, X Wang, X Shen, ES McKenna, ME Lemieux, YJ Cho, ... Cancer cell 18 (4), 316-328, 2010 | 686 | 2010 |
Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells X Shen, W Kim, Y Fujiwara, MD Simon, Y Liu, MR Mysliwiec, GC Yuan, ... cell 139 (7), 1303-1314, 2009 | 470 | 2009 |
A LINE1-nucleolin partnership regulates early development and ESC identity M Percharde, CJ Lin, Y Yin, J Guan, GA Peixoto, A Bulut-Karslioglu, ... Cell 174 (2), 391-405. e19, 2018 | 421 | 2018 |
The unfolded protein response—a stress signaling pathway of the endoplasmic reticulum X Shen, K Zhang, RJ Kaufman Journal of chemical neuroanatomy 28 (1-2), 79-92, 2004 | 395 | 2004 |
Divergent lncRNAs regulate gene expression and lineage differentiation in pluripotent cells S Luo, JY Lu, L Liu, Y Yin, C Chen, X Han, B Wu, R Xu, W Liu, P Yan, ... Cell stem cell 18 (5), 637-652, 2016 | 382 | 2016 |
PRC2 directly methylates GATA4 and represses its transcriptional activity A He, X Shen, Q Ma, J Cao, A von Gise, P Zhou, G Wang, VE Marquez, ... Genes & development 26 (1), 37-42, 2012 | 310 | 2012 |
Opposing roles for the lncRNA haunt and its genomic locus in regulating HOXA gene activation during embryonic stem cell differentiation Y Yin, P Yan, J Lu, G Song, Y Zhu, Z Li, Y Zhao, B Shen, X Huang, H Zhu, ... Cell stem cell 16 (5), 504-516, 2015 | 290 | 2015 |
Genetic Interactions Due to Constitutive and Inducible Gene Regulation Mediated by the Unfolded Protein Response in C. elegans X Shen, RE Ellis, K Sakaki, RJ Kaufman PLoS genetics 1 (3), e37, 2005 | 283 | 2005 |
Complementation of the Arabidopsis pds1 mutation with the gene encoding p-hydroxyphenylpyruvate dioxygenase SR Norris, X Shen, D Della Penna Plant physiology 117 (4), 1317-1323, 1998 | 250 | 1998 |
U1 snRNP regulates chromatin retention of noncoding RNAs Y Yin, JY Lu, X Zhang, W Shao, Y Xu, P Li, Y Hong, L Cui, G Shan, B Tian, ... Nature 580 (7801), 147-150, 2020 | 179 | 2020 |
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1 W Lin, J Cao, J Liu, ML Beshiri, Y Fujiwara, J Francis, AD Cherniack, ... Proceedings of the National Academy of Sciences 108 (33), 13379-13386, 2011 | 163 | 2011 |
Cis-and trans-acting lncRNAs in pluripotency and reprogramming P Yan, S Luo, JY Lu, X Shen Current opinion in genetics & development 46, 170-178, 2017 | 149 | 2017 |
RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells D Guallar, X Bi, JA Pardavila, X Huang, C Saenz, X Shi, H Zhou, F Faiola, ... Nature genetics 50 (3), 443-451, 2018 | 138 | 2018 |