| Targeting metabolism for cancer therapy A Luengo, DY Gui, MG Vander Heiden Cell chemical biology 24 (9), 1161-1180, 2017 | 830 | 2017 |
| Environment impacts the metabolic dependencies of Ras-driven non-small cell lung cancer SM Davidson, T Papagiannakopoulos, BA Olenchock, JE Heyman, ... Cell metabolism 23 (3), 517-528, 2016 | 695 | 2016 |
| A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate ME Pacold, KR Brimacombe, SH Chan, JM Rohde, CA Lewis, ... Nature chemical biology 12 (6), 452-458, 2016 | 465 | 2016 |
| Environment dictates dependence on mitochondrial complex I for NAD+ and aspartate production and determines cancer cell sensitivity to metformin DY Gui, LB Sullivan, A Luengo, AM Hosios, LN Bush, N Gitego, ... Cell metabolism 24 (5), 716-727, 2016 | 319 | 2016 |
| Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors SM Davidson, O Jonas, MA Keibler, HW Hou, A Luengo, JR Mayers, ... Nature medicine 23 (2), 235-241, 2017 | 299 | 2017 |
| Aspartate is an endogenous metabolic limitation for tumour growth LB Sullivan, A Luengo, LV Danai, LN Bush, FF Diehl, AM Hosios, AN Lau, ... Nature cell biology 20 (7), 782-788, 2018 | 286 | 2018 |
| Increased demand for NAD+ relative to ATP drives aerobic glycolysis A Luengo, Z Li, DY Gui, LB Sullivan, M Zagorulya, BT Do, R Ferreira, ... Molecular cell 81 (4), 691-707. e6, 2021 | 283 | 2021 |
| Limited environmental serine and glycine confer brain metastasis sensitivity to PHGDH inhibition B Ngo, E Kim, V Osorio-Vasquez, S Doll, S Bustraan, RJ Liang, A Luengo, ... Cancer discovery 10 (9), 1352-1373, 2020 | 168 | 2020 |
| Fatty acid synthesis is required for breast cancer brain metastasis GB Ferraro, A Ali, A Luengo, DP Kodack, A Deik, KL Abbott, D Bezwada, ... Nature cancer 2 (4), 414-428, 2021 | 164 | 2021 |
| Cytosolic aspartate availability determines cell survival when glutamine is limiting HF Alkan, KE Walter, A Luengo, CT Madreiter-Sokolowski, S Stryeck, ... Cell metabolism 28 (5), 706-720. e6, 2018 | 144 | 2018 |
| Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma TL Dayton, V Gocheva, KM Miller, WJ Israelsen, A Bhutkar, CB Clish, ... Genes & development 30 (9), 1020-1033, 2016 | 137 | 2016 |
| Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy A Luengo, LB Sullivan, MGV Heiden BMC biology 12, 1-4, 2014 | 116 | 2014 |
| Deoxycytidine release from pancreatic stellate cells promotes gemcitabine resistance S Dalin, MR Sullivan, AN Lau, B Grauman-Boss, HS Mueller, E Kreidl, ... Cancer research 79 (22), 5723-5733, 2019 | 109 | 2019 |
| Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer A Luengo, KL Abbott, SM Davidson, AM Hosios, B Faubert, SH Chan, ... Nature communications 10 (1), 5604, 2019 | 51 | 2019 |
| Migration responses of outer and inner meniscus cells to applied direct current electric fields NJ Gunja, D Dujari, A Chen, A Luengo, JV Fong, CT Hung Journal of Orthopaedic Research 30 (1), 103-111, 2012 | 34 | 2012 |
| REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks N Chatterjee, MA Whitman, CA Harris, SM Min, O Jonas, EC Lien, ... Proceedings of the National Academy of Sciences 117 (46), 28918-28921, 2020 | 32 | 2020 |
| The angiotensin receptor blocker and partial PPAR. agonist telmisartan inhibits the growth of pancreatic ductal adenocarcinoma J Grahovac, S Han, H Liu, M Duquette, A Luengo, D Schanne, AS Liss, ... CANCER RESEARCH 79 (24), 2019 | 1* | 2019 |
| Fatty acid synthesis is required for breast cancer brain metastasis (vol 2, pg 414, 2021) GB Ferraro, A Ali, A Luengo, DP Kodack, A Deik, KL Abbott, D Bezwada, ... NATURE CANCER 2 (11), 1243-1243, 2021 | | 2021 |
| Examining metabolic vulnerabilities for cancer therapy A Luengo Massachusetts Institute of Technology, 2018 | | 2018 |
Lucas B SullivanAssistant Professor, Fred Hutchinson Cancer Research CenterVerifisert e-postadresse på fredhutch.org
