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Kaushik Dutta
Kaushik Dutta
Senior Principal Scientist
Verified email at pfizer.com
Title
Cited by
Cited by
Year
A small molecule RAS-mimetic disrupts RAS association with effector proteins to block signaling
SK Athuluri-Divakar, R Vasquez-Del Carpio, K Dutta, SJ Baker, ...
Cell 165 (3), 643-655, 2016
2672016
Mapping structural interactions using in-cell NMR spectroscopy (STINT-NMR)
DS Burz, K Dutta, D Cowburn, A Shekhtman
Nature methods 3 (2), 91-93, 2006
2162006
The molecular mechanism of nuclear transport revealed by atomic-scale measurements
LE Hough, K Dutta, S Sparks, DB Temel, A Kamal, J Tetenbaum-Novatt, ...
Elife 4, e10027, 2015
1542015
In-cell NMR for protein-protein interactions (STINT-NMR)
DS Burz, K Dutta, D Cowburn, A Shekhtman
Nature protocols 1 (1), 146-152, 2006
1082006
The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition
J Kalinina, K Dutta, D Ilghari, A Beenken, R Goetz, AV Eliseenkova, ...
Structure 20 (1), 77-88, 2012
1032012
Slide-and-exchange mechanism for rapid and selective transport through the nuclear pore complex
B Raveh, JM Karp, S Sparks, K Dutta, MP Rout, A Sali, D Cowburn
Proceedings of the National Academy of Sciences 113 (18), E2489-E2497, 2016
1012016
pH‐induced folding of an apoptotic coiled coil
K Dutta, A Alexandrov, H Huang, SM Pascal
Protein Science 10 (12), 2531-2540, 2001
912001
MBP fusion protein with a viral protease cleavage site: one-step cleavage/purification of insoluble proteins
A Alexandrov, K Dutta, SM Pascal
Biotechniques 30 (6), 1194-1198, 2001
872001
Generation, characterization, and epitope mapping of neutralizing and protective monoclonal antibodies against staphylococcal enterotoxin B-induced lethal shock
AK Varshney, X Wang, E Cook, K Dutta, MD Scharff, MJ Goger, BC Fries
Journal of biological chemistry 286 (11), 9737-9747, 2011
702011
A full-length group 1 bacterial sigma factor adopts a compact structure incompatible with DNA binding
EC Schwartz, A Shekhtman, K Dutta, MR Pratt, D Cowburn, S Darst, ...
Chemistry & biology 15 (10), 1091-1103, 2008
692008
Molecular architecture of the major membrane ring component of the nuclear pore complex
P Upla, SJ Kim, P Sampathkumar, K Dutta, SM Cahill, IE Chemmama, ...
Structure 25 (3), 434-445, 2017
652017
The regions of securin and cyclin B proteins recognized by the ubiquitination machinery are natively unfolded
CJ Cox, K Dutta, ET Petri, WC Hwang, Y Lin, SM Pascal, R Basavappa
FEBS letters 527 (1-3), 303-308, 2002
642002
Solution Structure and Folding Characteristics of the C-Terminal SH3 Domain of c-Crk-II,
V Muralidharan, K Dutta, J Cho, M Vila-Perello, DP Raleigh, D Cowburn, ...
Biochemistry 45 (29), 8874-8884, 2006
592006
Local control of a disorder–order transition in 4E-BP1 underpins regulation of translation via eIF4E
S Tait, K Dutta, D Cowburn, J Warwicker, AJ Doig, JEG McCarthy
Proceedings of the National Academy of Sciences 107 (41), 17627-17632, 2010
562010
Cracking the molecular origin of intrinsic tyrosine kinase activity through analysis of pathogenic gain-of-function mutations
H Chen, Z Huang, K Dutta, S Blais, TA Neubert, X Li, D Cowburn, ...
Cell reports 4 (2), 376-384, 2013
532013
Structure and dynamics of the second CARD of human RIG-I provide mechanistic insights into regulation of RIG-I activation
F Ferrage, K Dutta, E Nistal-Villán, JR Patel, MT Sánchez-Aparicio, ...
Structure 20 (12), 2048-2061, 2012
492012
Complete spectral assignments and microstructures of photopolymerized acrylonitrile/methacrylic acid copolymers by NMR spectroscopy
AS Brar, K Dutta, GS Kapur
Macromolecules 28 (26), 8735-8741, 1995
471995
Poly (vinylpyrrolidone): Configurational assignments by one‐and two‐dimensional NMR spectroscopy
K Dutta, AS Brar
Journal of Polymer Science Part A: Polymer Chemistry 37 (21), 3922-3928, 1999
431999
Monoclonal antibodies protect from Staphylococcal Enterotoxin K (SEK) induced toxic shock and sepsis by USA300 Staphylococcus aureus
JL Aguilar, AK Varshney, X Pechuan, K Dutta, JD Nosanchuk, BC Fries
Virulence 8 (6), 741-750, 2017
412017
Mechanisms Mediating Enhanced Neutralization Efficacy of Staphylococcal Enterotoxin B by Combinations of Monoclonal Antibodies
BF K Dutta, AK Varshney, M Franklin, M Goger, X Wang
Journal of Biological Chemistry 290 (11), 6715-6730, 2015
402015
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Articles 1–20