Long-term, multilineage hematopoiesis occurs in the combined absence of β-catenin and γ-catenin G Jeannet, M Scheller, L Scarpellino, S Duboux, N Gardiol, J Back, ... Blood, The Journal of the American Society of Hematology 111 (1), 142-149, 2008 | 272 | 2008 |
PU. 1 determines the self-renewal capacity of erythroid progenitor cells J Back, A Dierich, C Bronn, P Kastner, S Chan Blood 103 (10), 3615-3623, 2004 | 170 | 2004 |
A Role for cis Interaction between the Inhibitory Ly49A receptor and MHC class I for natural killer cell education A Chalifour, L Scarpellino, J Back, P Brodin, E Devèvre, F Gros, F Lévy, ... Immunity 30 (3), 337-347, 2009 | 166 | 2009 |
GBR 830, an anti-OX40, improves skin gene signatures and clinical scores in patients with atopic dermatitis E Guttman-Yassky, AB Pavel, L Zhou, YD Estrada, N Zhang, H Xu, X Peng, ... Journal of Allergy and Clinical Immunology 144 (2), 482-493. e7, 2019 | 164 | 2019 |
Enhanced bone formation in lipodystrophic PPARγhyp/hyp mice relocates haematopoiesis to the spleen TA Cock, J Back, F Elefteriou, G Karsenty, P Kastner, S Chan, J Auwerx EMBO reports 5 (10), 1007-1012, 2004 | 144 | 2004 |
Visualizing PU. 1 activity during hematopoiesis J Back, D Allman, S Chan, P Kastner Experimental hematology 33 (4), 395-402, 2005 | 138 | 2005 |
Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis J Back, EL Malchiodi, S Cho, L Scarpellino, P Schneider, MC Kerzic, ... Immunity 31 (4), 598-608, 2009 | 82 | 2009 |
Stable masking by H-2Dd cis ligand limits Ly49A relocalization to the site of NK cell/target cell contact J Back, A Chalifour, L Scarpellino, W Held Proceedings of the National Academy of Sciences 104 (10), 3978-3983, 2007 | 60 | 2007 |
Education of murine NK cells requires both cis and trans recognition of MHC class I molecules S Bessoles, GS Angelov, J Back, G Leclercq, E Vivier, W Held The Journal of Immunology 191 (10), 5044-5051, 2013 | 54 | 2013 |
The p53 tumour suppressor inhibits glucocorticoid-induced proliferation of erythroid progenitors G Ganguli, J Back, S Sengupta, B Wasylyk EMBO reports 3 (6), 569-574, 2002 | 53 | 2002 |
A novel anti-CD19 monoclonal antibody (GBR 401) with high killing activity against B cell malignancies CS Breton, A Nahimana, D Aubry, J Macoin, P Moretti, M Bertschinger, ... Journal of hematology & oncology 7, 1-13, 2014 | 43 | 2014 |
Antibodies that bind to OX40 and their uses A Attinger, S Blein, JA Back, R Lissilaa, S Hou US Patent 8,748,585, 2014 | 38 | 2014 |
Phase 1, multicenter, open-label study of single-agent bispecific antibody T-cell engager GBR 1342 in relapsed/refractory multiple myeloma JR Richter, CO Landgren, JS Kauh, J Back, Y Salhi, V Reddy, E Bayever, ... J Clin Oncol 36 (15 suppl), TPS3132, 2018 | 34 | 2018 |
Antibodies that bind to TL1A and their uses A Attinger, JA Back, S Blein, R Lissilaa, D Skegro US Patent 9,290,576, 2016 | 16 | 2016 |
Preliminary results from a phase I study of GBR 1302, a bispecific antibody T-cell engager M Wermke, J Alt, J Kauh, J Back, Y Salhi, V Reddy, M Barve, ... HER2 positive cancers. Ann Oncol 29, 2018 | 13 | 2018 |
Antibodies that bind to ox40 and their uses A Attinger, S Blein, JA Back, R Lissilaa, S Hou US Patent App. 14/222,421, 2014 | 13 | 2014 |
The interaction with H-2Dd in cis is associated with a conformational change in the Ly49A NK cell receptor J Back, GS Angelov, RA Mariuzza, W Held Frontiers in immunology 2, 13082, 2011 | 13 | 2011 |
Preliminary biomarker and pharmacodynamic data from a phase 1 study of single-agent bispecific antibody t cell engager gbr 1302 in subjects with her2-positive cancers M Wermke, J Alt, J KAUH, J Back, Y Salhi, V Reddy, E Bayever, ... J Clin Oncol 36 (5 Suppl), 69, 2018 | 12 | 2018 |
GBR1302: Effect of CD3-HER2, a bispecific T cell engager antibody, in trastuzumab-resistant cancers J Back, M Wermke, J Macoin, A Croset, JS Kauh, V Reddy J. Clin. Oncol 36, 12053, 2018 | 10 | 2018 |
Antibodies that bind to tl1a and their uses A Attinger, JA Back, S Blein, R Lissilaa, D Skegro US Patent App. 15/589,020, 2018 | 9 | 2018 |